(data stored in ACNUC1104 zone)

SWISSPROT: A4F616_SACEN

ID   A4F616_SACEN            Unreviewed;       228 AA.
AC   A4F616;
DT   17-APR-2007, integrated into UniProtKB/TrEMBL.
DT   17-APR-2007, sequence version 1.
DT   08-MAY-2019, entry version 66.
DE   SubName: Full=DNA-binding IclR family transcriptional regulator {ECO:0000313|EMBL:PFG93289.1};
DE   SubName: Full=Differentiation regulon (IclR-family transcriptional regulator) {ECO:0000313|EMBL:CAL99490.1};
GN   Name=sdrB {ECO:0000313|EMBL:CAL99490.1};
GN   OrderedLocusNames=SACE_0137 {ECO:0000313|EMBL:CAL99490.1};
GN   ORFNames=A8924_0523 {ECO:0000313|EMBL:PFG93289.1};
OS   Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748
OS   / NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC   Bacteria; Actinobacteria; Pseudonocardiales; Pseudonocardiaceae;
OC   Saccharopolyspora.
OX   NCBI_TaxID=405948 {ECO:0000313|EMBL:CAL99490.1, ECO:0000313|Proteomes:UP000006728};
RN   [1] {ECO:0000313|EMBL:CAL99490.1, ECO:0000313|Proteomes:UP000006728}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC   NRRL 2338 {ECO:0000313|Proteomes:UP000006728}, and NRRL 2338
RC   {ECO:0000313|EMBL:CAL99490.1};
RX   PubMed=17369815; DOI=10.1038/nbt1297;
RA   Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N.,
RA   Dickens S., Haydock S.F., Leadlay P.F.;
RT   "Complete genome sequence of the erythromycin-producing bacterium
RT   Saccharopolyspora erythraea NRRL23338.";
RL   Nat. Biotechnol. 25:447-453(2007).
RN   [2] {ECO:0000313|EMBL:PFG93289.1, ECO:0000313|Proteomes:UP000225825}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 40517 {ECO:0000313|EMBL:PFG93289.1,
RC   ECO:0000313|Proteomes:UP000225825};
RA   Klenk H.-P.;
RT   "Sequencing the genomes of 1000 actinobacteria strains.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AM420293; CAL99490.1; -; Genomic_DNA.
DR   EMBL; PDBV01000001; PFG93289.1; -; Genomic_DNA.
DR   RefSeq; WP_009949273.1; NZ_PDBV01000001.1.
DR   STRING; 405948.SACE_0137; -.
DR   EnsemblBacteria; CAL99490; CAL99490; SACE_0137.
DR   KEGG; sen:SACE_0137; -.
DR   eggNOG; ENOG4108WBQ; Bacteria.
DR   eggNOG; ENOG4111IKG; LUCA.
DR   HOGENOM; HOG000107041; -.
DR   OMA; VNRTVVY; -.
DR   OrthoDB; 370329at2; -.
DR   BioCyc; SERY405948:SACE_RS00655-MONOMER; -.
DR   Proteomes; UP000006728; Chromosome.
DR   Proteomes; UP000225825; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR   InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF09339; HTH_IclR; 1.
DR   SMART; SM00346; HTH_ICLR; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS51077; HTH_ICLR; 1.
DR   PROSITE; PS51078; ICLR_ED; 1.
PE   4: Predicted;
DR   PRODOM; A4F616.
DR   SWISS-2DPAGE; A4F616.
KW   Complete proteome {ECO:0000313|Proteomes:UP000006728,
KW   ECO:0000313|Proteomes:UP000225825};
KW   DNA-binding {ECO:0000313|EMBL:PFG93289.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006728}.
FT   DOMAIN       25     88       HTH iclR-type. {ECO:0000259|PROSITE:
FT                                PS51077}.
FT   DOMAIN       87    228       IclR-ED. {ECO:0000259|PROSITE:PS51078}.
SQ   SEQUENCE   228 AA;  23447 MW;  ADFC679508232A65 CRC64;
     MAFTPEPTRS PVTRAPGDAP AKESSLTLER GLNLLQAVAD AESEAPTISD LAAAIGVSRA
     AVYRLLGPLQ NRGLVRREGS KVRLGLGVLW LAGRVLPQLR VASLPALRGL AEQVGATVHL
     TVADGGEAQA VAVVEPSWTN YHVSYRVGTR HPVHRGAAGR AVDLPPGGPR WVSSTGELQS
     GAFGVAAPVR GVPGLRASVG IVALVPVSPE EIGPLVLETA EAVAAALK
//

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