(data stored in SCRATCH zone)

SWISSPROT: A4F6H8_SACEN

ID   A4F6H8_SACEN            Unreviewed;       187 AA.
AC   A4F6H8;
DT   17-APR-2007, integrated into UniProtKB/TrEMBL.
DT   17-APR-2007, sequence version 1.
DT   11-DEC-2019, entry version 75.
DE   SubName: Full=TetR family transcriptional regulator {ECO:0000313|EMBL:PFG93455.1};
DE   SubName: Full=Transcriptional regulator, TetR family {ECO:0000313|EMBL:CAL99652.1};
GN   OrderedLocusNames=SACE_0303 {ECO:0000313|EMBL:CAL99652.1};
GN   ORFNames=A8924_0697 {ECO:0000313|EMBL:PFG93455.1};
OS   Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 /
OS   NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC   Bacteria; Actinobacteria; Pseudonocardiales; Pseudonocardiaceae;
OC   Saccharopolyspora.
OX   NCBI_TaxID=405948 {ECO:0000313|EMBL:CAL99652.1, ECO:0000313|Proteomes:UP000006728};
RN   [1] {ECO:0000313|EMBL:CAL99652.1, ECO:0000313|Proteomes:UP000006728}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC   NRRL 2338 {ECO:0000313|Proteomes:UP000006728}, and NRRL 2338
RC   {ECO:0000313|EMBL:CAL99652.1};
RX   PubMed=17369815; DOI=10.1038/nbt1297;
RA   Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S.,
RA   Haydock S.F., Leadlay P.F.;
RT   "Complete genome sequence of the erythromycin-producing bacterium
RT   Saccharopolyspora erythraea NRRL23338.";
RL   Nat. Biotechnol. 25:447-453(2007).
RN   [2] {ECO:0000313|EMBL:PFG93455.1, ECO:0000313|Proteomes:UP000225825}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 40517 {ECO:0000313|EMBL:PFG93455.1,
RC   ECO:0000313|Proteomes:UP000225825};
RA   Klenk H.-P.;
RT   "Sequencing the genomes of 1000 actinobacteria strains.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AM420293; CAL99652.1; -; Genomic_DNA.
DR   EMBL; PDBV01000001; PFG93455.1; -; Genomic_DNA.
DR   RefSeq; WP_009946947.1; NZ_PDBV01000001.1.
DR   STRING; 405948.SACE_0303; -.
DR   EnsemblBacteria; CAL99652; CAL99652; SACE_0303.
DR   KEGG; sen:SACE_0303; -.
DR   eggNOG; ENOG4105SSE; Bacteria.
DR   eggNOG; ENOG4111YAR; LUCA.
DR   HOGENOM; HOG000046759; -.
DR   OMA; PWAGFAR; -.
DR   OrthoDB; 1437290at2; -.
DR   BioCyc; SERY405948:SACE_RS01480-MONOMER; -.
DR   Proteomes; UP000006728; Chromosome.
DR   Proteomes; UP000225825; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001647; HTH_TetR.
DR   Pfam; PF00440; TetR_N; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS50977; HTH_TETR_2; 1.
PE   4: Predicted;
DR   PRODOM; A4F6H8.
DR   SWISS-2DPAGE; A4F6H8.
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335,
KW   ECO:0000256|SAAS:SAAS00132209};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006728};
KW   Transcription {ECO:0000256|SAAS:SAAS00131596};
KW   Transcription regulation {ECO:0000256|SAAS:SAAS00132066}.
FT   DOMAIN          7..67
FT                   /note="HTH tetR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50977"
FT   DNA_BIND        30..49
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ   SEQUENCE   187 AA;  20759 MW;  4AD516F52E562147 CRC64;
     MTRTDESRRR RELLSKLLEY SADHGLSEVS LRPLAAAVGS SPRMLLYFFG SKEGLVREVH
     RHAREAQLAL LADALGDRLA TGSRADALRA LWEWLSDPAH HNVVRFFFES YARSLHARED
     AWEGFGEASV REWLPHIRRA LGSSDAEATL VLAALRGLML DLLATGDTER VRAGFESLVA
     GLPVEPA
//

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