(data stored in SCRATCH zone)

SWISSPROT: A4F6M8_SACEN

ID   A4F6M8_SACEN            Unreviewed;       308 AA.
AC   A4F6M8;
DT   17-APR-2007, integrated into UniProtKB/TrEMBL.
DT   17-APR-2007, sequence version 1.
DT   11-DEC-2019, entry version 70.
DE   SubName: Full=RpiR-family transcriptional regulator {ECO:0000313|EMBL:CAL99702.1, ECO:0000313|EMBL:PFG93505.1};
GN   OrderedLocusNames=SACE_0353 {ECO:0000313|EMBL:CAL99702.1};
GN   ORFNames=A8924_0748 {ECO:0000313|EMBL:PFG93505.1};
OS   Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 /
OS   NBRC 13426 / NCIMB 8594 / NRRL 2338).
OC   Bacteria; Actinobacteria; Pseudonocardiales; Pseudonocardiaceae;
OC   Saccharopolyspora.
OX   NCBI_TaxID=405948 {ECO:0000313|EMBL:CAL99702.1, ECO:0000313|Proteomes:UP000006728};
RN   [1] {ECO:0000313|EMBL:CAL99702.1, ECO:0000313|Proteomes:UP000006728}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 /
RC   NRRL 2338 {ECO:0000313|Proteomes:UP000006728}, and NRRL 2338
RC   {ECO:0000313|EMBL:CAL99702.1};
RX   PubMed=17369815; DOI=10.1038/nbt1297;
RA   Oliynyk M., Samborskyy M., Lester J.B., Mironenko T., Scott N., Dickens S.,
RA   Haydock S.F., Leadlay P.F.;
RT   "Complete genome sequence of the erythromycin-producing bacterium
RT   Saccharopolyspora erythraea NRRL23338.";
RL   Nat. Biotechnol. 25:447-453(2007).
RN   [2] {ECO:0000313|EMBL:PFG93505.1, ECO:0000313|Proteomes:UP000225825}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 40517 {ECO:0000313|EMBL:PFG93505.1,
RC   ECO:0000313|Proteomes:UP000225825};
RA   Klenk H.-P.;
RT   "Sequencing the genomes of 1000 actinobacteria strains.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AM420293; CAL99702.1; -; Genomic_DNA.
DR   EMBL; PDBV01000001; PFG93505.1; -; Genomic_DNA.
DR   RefSeq; WP_009946498.1; NZ_PDBV01000001.1.
DR   STRING; 405948.SACE_0353; -.
DR   EnsemblBacteria; CAL99702; CAL99702; SACE_0353.
DR   KEGG; sen:SACE_0353; -.
DR   eggNOG; ENOG4106KNT; Bacteria.
DR   eggNOG; COG1737; LUCA.
DR   HOGENOM; HOG000027157; -.
DR   OMA; RGPRFRE; -.
DR   OrthoDB; 992687at2; -.
DR   BioCyc; SERY405948:SACE_RS01730-MONOMER; -.
DR   Proteomes; UP000006728; Chromosome.
DR   Proteomes; UP000225825; Unassembled WGS sequence.
DR   GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR   CDD; cd05013; SIS_RpiR; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR000281; HTH_RpiR.
DR   InterPro; IPR035472; RpiR-like_SIS.
DR   InterPro; IPR001347; SIS.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF01418; HTH_6; 1.
DR   Pfam; PF01380; SIS; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS51071; HTH_RPIR; 1.
DR   PROSITE; PS51464; SIS; 1.
PE   4: Predicted;
DR   PRODOM; A4F6M8.
DR   SWISS-2DPAGE; A4F6M8.
KW   Reference proteome {ECO:0000313|Proteomes:UP000006728}.
FT   DOMAIN          13..89
FT                   /note="HTH rpiR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51071"
FT   DOMAIN          136..276
FT                   /note="SIS"
FT                   /evidence="ECO:0000259|PROSITE:PS51464"
SQ   SEQUENCE   308 AA;  32846 MW;  63481D7991089717 CRC64;
     MVTDDTLPES GEASPLIRIR SLLPGLARAE QRVANIVLAD PASVARRSIT EVAEAAGTSE
     TTVTRFCKAI GVGGYPDLRI ALAADTARTS SRDRDLGSDI GPEDDVRKII EKVSYADAKA
     VEETADQLDA ETLRSLVDAV ARARRIDVYG VGASAFVALD LQQKLHRIGL TCFAWSDTHN
     ALTSAAVLRE GDVAIGISHT GATTETVEAL QEAGKRGATT AALTNFARSP ITEVADHVLT
     TAVRETTYRS GAMASRIGQL TVIDCLFIGV AQRHLDQTKA ALEATYEAVG AHRLGARPDR
     RRQKEDGR
//

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