(data stored in ACNUC8465 zone)

SWISSPROT: B6HG16_PENRW

ID   B6HG16_PENRW            Unreviewed;       283 AA.
AC   B6HG16;
DT   16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT   16-DEC-2008, sequence version 1.
DT   10-APR-2019, entry version 49.
DE   RecName: Full=25S rRNA adenine-N(1) methyltransferase {ECO:0000256|HAMAP-Rule:MF_03044};
DE            EC=2.1.1.- {ECO:0000256|HAMAP-Rule:MF_03044};
GN   ORFNames=Pc20g00690 {ECO:0000313|EMBL:CAP85398.1}, PCH_Pc20g00690
GN   {ECO:0000313|EMBL:CAP85398.1};
OS   Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 /
OS   Wisconsin 54-1255) (Penicillium chrysogenum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC   Penicillium chrysogenum species complex.
OX   NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP85398.1, ECO:0000313|Proteomes:UP000000724};
RN   [1] {ECO:0000313|EMBL:CAP85398.1, ECO:0000313|Proteomes:UP000000724}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC   {ECO:0000313|Proteomes:UP000000724};
RX   PubMed=18820685; DOI=10.1038/nbt.1498;
RA   van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA   Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA   Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA   Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A.,
RA   van der Klei I.J., van Peij N.N.M.E., Veenhuis M., von Doehren H.,
RA   Wagner C., Wortman J.R., Bovenberg R.A.L.;
RT   "Genome sequencing and analysis of the filamentous fungus Penicillium
RT   chrysogenum.";
RL   Nat. Biotechnol. 26:1161-1168(2008).
CC   -!- FUNCTION: S-adenosyl-L-methionine-dependent methyltransferase that
CC       specifically methylates the N(1) position of an adenine present in
CC       helix 65 in 25S rRNA. {ECO:0000256|HAMAP-Rule:MF_03044}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000256|HAMAP-
CC       Rule:MF_03044}.
CC   -!- SIMILARITY: Belongs to the BMT2 family. {ECO:0000256|HAMAP-
CC       Rule:MF_03044}.
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DR   EMBL; AM920435; CAP85398.1; -; Genomic_DNA.
DR   RefSeq; XP_002562631.1; XM_002562585.1.
DR   STRING; 1108849.XP_002562631.1; -.
DR   EnsemblFungi; CAP85398; CAP85398; PCH_Pc20g00690.
DR   GeneID; 8307726; -.
DR   KEGG; pcs:Pc20g00690; -.
DR   eggNOG; ENOG410IFK0; Eukaryota.
DR   eggNOG; ENOG4111MRW; LUCA.
DR   HOGENOM; HOG000171862; -.
DR   KO; K18849; -.
DR   OMA; GGKMAYW; -.
DR   OrthoDB; 1471671at2759; -.
DR   BioCyc; PCHR:PC20G00690-MONOMER; -.
DR   Proteomes; UP000000724; Contig Pc00c20.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0016433; F:rRNA (adenine) methyltransferase activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_03044; BMT2; 1.
DR   InterPro; IPR021867; Bmt2/SAMTOR.
DR   InterPro; IPR029063; SAM-dependent_MTases.
DR   PANTHER; PTHR21008; PTHR21008; 1.
DR   Pfam; PF11968; Bmt2; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
PE   3: Inferred from homology;
DR   PRODOM; B6HG16.
DR   SWISS-2DPAGE; B6HG16.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000724};
KW   Methyltransferase {ECO:0000256|HAMAP-Rule:MF_03044};
KW   Nucleus {ECO:0000256|HAMAP-Rule:MF_03044};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000724};
KW   S-adenosyl-L-methionine {ECO:0000256|HAMAP-Rule:MF_03044};
KW   Transferase {ECO:0000256|HAMAP-Rule:MF_03044}.
FT   BINDING     119    119       S-adenosyl-L-methionine.
FT                                {ECO:0000256|HAMAP-Rule:MF_03044}.
FT   BINDING     139    139       S-adenosyl-L-methionine.
FT                                {ECO:0000256|HAMAP-Rule:MF_03044}.
SQ   SEQUENCE   283 AA;  31666 MW;  E9EA8DD9AB1CE736 CRC64;
     MAPQKRSKRP MLLSHSRPRI VKSKDAALSA KATRTLIRTH HRLLKVRAQA LAAGDEARVS
     SIDAQIEANG GLESYQIASK LGQSMDRGGD SSKVLIDWIK PQLKQWNKAI PKLRVLEVGA
     LSTKNACSTH PALDVTRIDL NSQEPGILKQ DFMERPLPSS DDERFNIISL SLVLNYVPDA
     TGRGEMLKHC VKFLTSKCPI ELVPSLFMVL PIACVDNSRY LNEERLGEIL TCLGFRLAQS
     KRTSKLVFHL WEHTGTYAPK AFKKEELRSG KTRNNFAVIL NKK
//

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