(data stored in SCRATCH zone)

SWISSPROT: B6HD69_PENRW

ID   B6HD69_PENRW            Unreviewed;       227 AA.
AC   B6HD69;
DT   16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT   16-DEC-2008, sequence version 1.
DT   08-MAY-2019, entry version 50.
DE   RecName: Full=Protein ROT1 {ECO:0000256|PIRNR:PIRNR017290};
GN   ORFNames=Pc20g01320 {ECO:0000313|EMBL:CAP85461.1}, PCH_Pc20g01320
GN   {ECO:0000313|EMBL:CAP85461.1};
OS   Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 /
OS   Wisconsin 54-1255) (Penicillium chrysogenum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC   Penicillium chrysogenum species complex.
OX   NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP85461.1, ECO:0000313|Proteomes:UP000000724};
RN   [1] {ECO:0000313|EMBL:CAP85461.1, ECO:0000313|Proteomes:UP000000724}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC   {ECO:0000313|Proteomes:UP000000724};
RX   PubMed=18820685; DOI=10.1038/nbt.1498;
RA   van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA   Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA   Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA   Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A.,
RA   van der Klei I.J., van Peij N.N.M.E., Veenhuis M., von Doehren H.,
RA   Wagner C., Wortman J.R., Bovenberg R.A.L.;
RT   "Genome sequencing and analysis of the filamentous fungus Penicillium
RT   chrysogenum.";
RL   Nat. Biotechnol. 26:1161-1168(2008).
CC   -!- FUNCTION: Required for normal levels of the cell wall 1,6-beta-
CC       glucan. Involved in a protein folding machinery chaperoning
CC       proteins acting in various physiological processes including cell
CC       wall synthesis and lysis of autophagic bodies.
CC       {ECO:0000256|PIRNR:PIRNR017290}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000256|PIRNR:PIRNR017290}.
CC   -!- SIMILARITY: Belongs to the ROT1 family.
CC       {ECO:0000256|PIRNR:PIRNR017290}.
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DR   EMBL; AM920435; CAP85461.1; -; Genomic_DNA.
DR   RefSeq; XP_002562691.1; XM_002562645.1.
DR   STRING; 1108849.XP_002562691.1; -.
DR   EnsemblFungi; CAP85461; CAP85461; PCH_Pc20g01320.
DR   GeneID; 8312269; -.
DR   KEGG; pcs:Pc20g01320; -.
DR   eggNOG; ENOG410IJWX; Eukaryota.
DR   eggNOG; ENOG4111IZT; LUCA.
DR   HOGENOM; HOG000246668; -.
DR   OMA; CPKGIMQ; -.
DR   OrthoDB; 1494547at2759; -.
DR   BioCyc; PCHR:PC20G01320-MONOMER; -.
DR   Proteomes; UP000000724; Contig Pc00c20.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006458; P:'de novo' protein folding; IEA:InterPro.
DR   InterPro; IPR019623; Rot1.
DR   PANTHER; PTHR28090; PTHR28090; 1.
DR   Pfam; PF10681; Rot1; 1.
DR   PIRSF; PIRSF017290; ROT1_prd; 1.
PE   3: Inferred from homology;
DR   PRODOM; B6HD69.
DR   SWISS-2DPAGE; B6HD69.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000724};
KW   Endoplasmic reticulum {ECO:0000256|PIRNR:PIRNR017290};
KW   Membrane {ECO:0000256|PIRNR:PIRNR017290};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000724};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     16       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        17    227       Protein ROT1. {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002845581.
SQ   SEQUENCE   227 AA;  25554 MW;  E3C35B215E7F9B46 CRC64;
     MFLIWGLLVT AALANANDLV GTWTTKSRDV LTGPGFYDPL NDKLLEPNLT GISYSFDDDG
     NYESAYYRAI SNPVDPSCPG GIMQWQHGSY TVFGNGTLIL TPIAVDGRQL LSDPCRQQSG
     QYTRYNTTEE FKEFSVYIDK FNRIKRLDLT KFDGSLVHPM FLAYQPPKML PTTTLNPMPT
     GHKQKRELSS KESGVYLVAR EQLVNPDRWW WLGVLMTSLG GVAFFCS
//

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