(data stored in SCRATCH zone)

SWISSPROT: B6HF55_PENRW

ID   B6HF55_PENRW            Unreviewed;      1368 AA.
AC   B6HF55;
DT   16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT   16-DEC-2008, sequence version 1.
DT   08-MAY-2019, entry version 57.
DE   RecName: Full=RNA-dependent RNA polymerase {ECO:0000256|RuleBase:RU363098};
DE            EC=2.7.7.48 {ECO:0000256|RuleBase:RU363098};
GN   ORFNames=Pc20g02950 {ECO:0000313|EMBL:CAP85624.1}, PCH_Pc20g02950
GN   {ECO:0000313|EMBL:CAP85624.1};
OS   Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 /
OS   Wisconsin 54-1255) (Penicillium chrysogenum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC   Penicillium chrysogenum species complex.
OX   NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP85624.1, ECO:0000313|Proteomes:UP000000724};
RN   [1] {ECO:0000313|EMBL:CAP85624.1, ECO:0000313|Proteomes:UP000000724}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC   {ECO:0000313|Proteomes:UP000000724};
RX   PubMed=18820685; DOI=10.1038/nbt.1498;
RA   van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA   Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA   Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA   Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A.,
RA   van der Klei I.J., van Peij N.N.M.E., Veenhuis M., von Doehren H.,
RA   Wagner C., Wortman J.R., Bovenberg R.A.L.;
RT   "Genome sequencing and analysis of the filamentous fungus Penicillium
RT   chrysogenum.";
RL   Nat. Biotechnol. 26:1161-1168(2008).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:11128, Rhea:RHEA-
CC         COMP:11129, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557,
CC         ChEBI:CHEBI:83400; EC=2.7.7.48;
CC         Evidence={ECO:0000256|RuleBase:RU363098};
CC   -!- SIMILARITY: Belongs to the RdRP family.
CC       {ECO:0000256|RuleBase:RU363098}.
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DR   EMBL; AM920435; CAP85624.1; -; Genomic_DNA.
DR   RefSeq; XP_002562848.1; XM_002562802.1.
DR   STRING; 1108849.XP_002562848.1; -.
DR   EnsemblFungi; CAP85624; CAP85624; PCH_Pc20g02950.
DR   GeneID; 8317524; -.
DR   KEGG; pcs:Pc20g02950; -.
DR   eggNOG; KOG0988; Eukaryota.
DR   eggNOG; ENOG410XQMQ; LUCA.
DR   HOGENOM; HOG000194403; -.
DR   KO; K11699; -.
DR   OMA; GAYFFCP; -.
DR   OrthoDB; 63910at2759; -.
DR   BioCyc; PCHR:PC20G02950-MONOMER; -.
DR   Proteomes; UP000000724; Contig Pc00c20.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003968; F:RNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR007855; RNA-dep_RNA_pol_euk-typ.
DR   PANTHER; PTHR23079; PTHR23079; 1.
DR   Pfam; PF05183; RdRP; 1.
DR   SUPFAM; SSF54928; SSF54928; 1.
PE   3: Inferred from homology;
DR   PRODOM; B6HF55.
DR   SWISS-2DPAGE; B6HF55.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000724};
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU363098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000724};
KW   RNA-binding {ECO:0000256|RuleBase:RU363098};
KW   RNA-directed RNA polymerase {ECO:0000256|RuleBase:RU363098};
KW   Transferase {ECO:0000256|RuleBase:RU363098}.
SQ   SEQUENCE   1368 AA;  155170 MW;  E960C7658419F1D2 CRC64;
     MTGPDLPSLQ HPKSNLLRMV PPNIPTPARR NPPVLDLPVR DWITWRSWRT CAVDLLNLPR
     EMNTHDIYDA FHRYGNMISI DLWEDASGRP DCKGRIRFKP PPTEEFWRTG SFGVKLRSGR
     VAVISLSVCC GDSNGTIQSP VRPDIQLPGE VELKTVQVDI GVLLGLSTFH SMQSFTNLAY
     PRCVVDVMRK CLFLYFRVGI RGSDTADVNQ HDHRVKITFL QLTQIYQQYD KATRERSLLI
     VLDSAAIWHR KAKDIQSTLT EPLSWREEDS WYRQTSVTHN PNSLKTLPAN LKKTGHIIDL
     GRWNVFKISF APDVDPNVRR VDDTSHYLMR VEEIFKDYNI TVQDGSHFVE KADRPVPVWH
     WIDFSESKSN KASALLQDLG NQNYLHLPFK VRYQLEVCLS QGYLSEFTMT REFIETLKGL
     GDDQATRLLE FVATEKKQYL APMEIFDLKF FKGVTDSRIP NYCCFMRTAR ITPTTIYYNT
     PTVDISNRVV REWSTKGTPG RFLRVRFTDE KTEGRINASQ RGCNDEVYTR VKRTLANGIA
     IGDRHYEFLA FGNSQFREHG AYFVAPDAGI SAGTIRAWMG QFNHIRNVAK YTARLGQCFS
     TTRAFTGSSV QTIPCDDIIR NGFTFSDGVG KISKFLAQMV TSQHDIKTLT GEPPSAFQFR
     LGGAKGMLVV STDPLPQEVH IRPSQQKFET SQAGLEIIRW SQYSLATLNR QIILVLSALG
     IPDEVFHSKL NTMLGSFHRA MLNDSKAINL LQKYIDPNQM TLTLAQMVSD GFRRNEEPFV
     NTMLELWKSW HLKHLKEKAK IAIDQGANVL GVMDETGVLK GYFRKELPSR RASYAEKLAA
     LPEIFVQVCR LDGGGEYEVI EGLCILARNP SLHPGDIRVV RAVNRSELHA LRDVVVLPQT
     GDQDIASMCS GGDLDGDDYL VIWDPNLIPA NWFVECMDYK GSKAPDLDHD VTVDEITSFF
     VTYMKNDCLP RIAHAHLAWA DRLPRGVWED KCIRLAQLHS DAVDYNKSGA HARMARSLDP
     KFWPHFMEKR FKRPSSIYKS TKILGQLYDA VITPDFVPKL EKPFDSRILE SPLAPASEAY
     MEYARELKAE FDMNMRQIMA QYEINTEFEV WSTFVLRHGF VIKDYKMQED LGRIVGTLRR
     GFRHQCYDKV GRDGGNIPAL VIAMYRVTQE QVAAALEARR NEALQREDVS IAEVNSTELP
     LISFPWIFPD VLGDVATGRA RQAMISDGQE SADSAKPIGE GLVFTHKQIL KIVEDMDGDI
     KSTAENMKLK DPKNMEPKAE AGSNSAPPDQ ELIARRRIDK TKPKQKSEDR DTGLYIEEDD
     EKEGGVAIGS AKTEEKIDKR EAVTEDIVEM EGDVKPSALD DLIKMIGG
//

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