(data stored in ACNUC8465 zone)

SWISSPROT: B6H1E0_PENRW

ID   B6H1E0_PENRW            Unreviewed;       351 AA.
AC   B6H1E0;
DT   16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT   16-DEC-2008, sequence version 1.
DT   10-APR-2019, entry version 49.
DE   RecName: Full=Post-GPI attachment to proteins factor 3 {ECO:0000256|RuleBase:RU365066};
GN   ORFNames=Pc13g02730 {ECO:0000313|EMBL:CAP91342.1}, PCH_Pc13g02730
GN   {ECO:0000313|EMBL:CAP91342.1};
OS   Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 /
OS   Wisconsin 54-1255) (Penicillium chrysogenum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC   Penicillium chrysogenum species complex.
OX   NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP91342.1, ECO:0000313|Proteomes:UP000000724};
RN   [1] {ECO:0000313|EMBL:CAP91342.1, ECO:0000313|Proteomes:UP000000724}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC   {ECO:0000313|Proteomes:UP000000724};
RX   PubMed=18820685; DOI=10.1038/nbt.1498;
RA   van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA   Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA   Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA   Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A.,
RA   van der Klei I.J., van Peij N.N.M.E., Veenhuis M., von Doehren H.,
RA   Wagner C., Wortman J.R., Bovenberg R.A.L.;
RT   "Genome sequencing and analysis of the filamentous fungus Penicillium
RT   chrysogenum.";
RL   Nat. Biotechnol. 26:1161-1168(2008).
CC   -!- FUNCTION: Involved in the lipid remodeling steps of GPI-anchor
CC       maturation. {ECO:0000256|RuleBase:RU365066}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000256|RuleBase:RU365066}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU365066}.
CC   -!- SIMILARITY: Belongs to the PGAP3 family.
CC       {ECO:0000256|RuleBase:RU365066}.
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DR   EMBL; AM920428; CAP91342.1; -; Genomic_DNA.
DR   RefSeq; XP_002558712.1; XM_002558666.1.
DR   STRING; 1108849.XP_002558712.1; -.
DR   EnsemblFungi; CAP91342; CAP91342; PCH_Pc13g02730.
DR   GeneID; 8314728; -.
DR   KEGG; pcs:Pc13g02730; -.
DR   eggNOG; KOG2970; Eukaryota.
DR   eggNOG; COG5237; LUCA.
DR   HOGENOM; HOG000210016; -.
DR   OMA; RFLGMQE; -.
DR   OrthoDB; 828384at2759; -.
DR   BioCyc; PCHR:PC13G02730-MONOMER; -.
DR   Proteomes; UP000000724; Contig Pc00c13.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0031227; C:intrinsic component of endoplasmic reticulum membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0006506; P:GPI anchor biosynthetic process; IEA:UniProtKB-UniRule.
DR   InterPro; IPR007217; Per1-like.
DR   PANTHER; PTHR13148; PTHR13148; 1.
DR   Pfam; PF04080; Per1; 1.
PE   3: Inferred from homology;
DR   PRODOM; B6H1E0.
DR   SWISS-2DPAGE; B6H1E0.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000724};
KW   Endoplasmic reticulum {ECO:0000256|RuleBase:RU365066};
KW   GPI-anchor biosynthesis {ECO:0000256|RuleBase:RU365066};
KW   Membrane {ECO:0000256|RuleBase:RU365066};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000724};
KW   Signal {ECO:0000256|RuleBase:RU365066};
KW   Transmembrane {ECO:0000256|RuleBase:RU365066};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU365066}.
FT   SIGNAL        1     28       {ECO:0000256|RuleBase:RU365066}.
FT   CHAIN        29    351       Post-GPI attachment to proteins factor 3.
FT                                {ECO:0000256|RuleBase:RU365066}.
FT                                /FTId=PRO_5016483618.
FT   TRANSMEM    125    143       Helical. {ECO:0000256|RuleBase:RU365066}.
FT   TRANSMEM    164    183       Helical. {ECO:0000256|RuleBase:RU365066}.
FT   TRANSMEM    195    218       Helical. {ECO:0000256|RuleBase:RU365066}.
FT   TRANSMEM    230    251       Helical. {ECO:0000256|RuleBase:RU365066}.
FT   TRANSMEM    257    279       Helical. {ECO:0000256|RuleBase:RU365066}.
FT   TRANSMEM    286    306       Helical. {ECO:0000256|RuleBase:RU365066}.
FT   TRANSMEM    318    337       Helical. {ECO:0000256|RuleBase:RU365066}.
SQ   SEQUENCE   351 AA;  40826 MW;  9E4E19C0F6CA084E CRC64;
     MNLGVGRANL YTLFAFVFLA SLIGKSNASL GDHLPDFKEC VQVCKTENCQ NGNSVLRMSN
     HHPNSSPRLA LLTSLALHHR LLLWTCPAEC DYTCQHVITD RRVSRDPPMI SPIVQFHGKW
     PFRRLLGMQE PFSVLFSFFN FAAHWHGMSR IQESIPAWHS LRPYYMMFGY IGLASWSFSM
     IFHMRDFPLT EKLDYWAAGA NVLYGLYLAV VRIFRLDLEN TPYRPTLRRF WTAICILLYT
     LHVGYLTFWS WDYTYNMIAN VVVGIIQNLM WTGFSIFRYR RLEKSWAAWP GMIVAWIIMA
     MSLELLDFPP WNGLIDAHSL WHLGTVVPAV WWYSFLIKDA QDDIAAHRLK A
//

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