(data stored in ACNUC8465 zone)

SWISSPROT: CIAO1_PENRW

ID   CIAO1_PENRW             Reviewed;         455 AA.
AC   B6H7A3;
DT   01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 1.
DT   07-JUN-2017, entry version 50.
DE   RecName: Full=Probable cytosolic iron-sulfur protein assembly protein 1 {ECO:0000255|HAMAP-Rule:MF_03037};
GN   Name=cia1; ORFNames=Pc16g01970;
OS   Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 /
OS   Wisconsin 54-1255) (Penicillium chrysogenum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC   Penicillium chrysogenum species complex.
OX   NCBI_TaxID=500485;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255;
RX   PubMed=18820685; DOI=10.1038/nbt.1498;
RA   van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA   Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA   Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA   Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A.,
RA   van der Klei I.J., van Peij N.N.M.E., Veenhuis M., von Doehren H.,
RA   Wagner C., Wortman J.R., Bovenberg R.A.L.;
RT   "Genome sequencing and analysis of the filamentous fungus Penicillium
RT   chrysogenum.";
RL   Nat. Biotechnol. 26:1161-1168(2008).
CC   -!- FUNCTION: Essential component of the cytosolic iron-sulfur (Fe/S)
CC       protein assembly machinery. Required for the maturation of
CC       extramitochondrial Fe/S proteins. {ECO:0000255|HAMAP-
CC       Rule:MF_03037}.
CC   -!- SIMILARITY: Belongs to the WD repeat CIA1 family.
CC       {ECO:0000255|HAMAP-Rule:MF_03037}.
DR   EMBL; AM920431; CAP92867.1; -; Genomic_DNA.
DR   RefSeq; XP_002560570.1; XM_002560524.1.
DR   ProteinModelPortal; B6H7A3; -.
DR   STRING; 500485.XP_002560570.1; -.
DR   EnsemblFungi; CAP92867; CAP92867; PCH_Pc16g01970.
DR   GeneID; 8313929; -.
DR   KEGG; pcs:Pc16g01970; -.
DR   eggNOG; KOG0645; Eukaryota.
DR   eggNOG; ENOG410XRMA; LUCA.
DR   HOGENOM; HOG000208901; -.
DR   OMA; VWKCVCT; -.
DR   OrthoDB; EOG092C4BLN; -.
DR   BioCyc; PCHR:PC16G01970-MONOMER; -.
DR   Proteomes; UP000000724; Contig Pc00c16.
DR   GO; GO:0097361; C:CIA complex; IEA:InterPro.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:InterPro.
DR   Gene3D; 2.130.10.10; -; 2.
DR   HAMAP; MF_03037; ciao1; 1.
DR   InterPro; IPR028608; CIAO1/Cia1.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR017986; WD40_repeat_dom.
DR   Pfam; PF00400; WD40; 3.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; SSF50978; 4.
DR   PROSITE; PS50082; WD_REPEATS_2; 4.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
DR   PRODOM; B6H7A3.
DR   SWISS-2DPAGE; B6H7A3.
KW   Complete proteome; Reference proteome; Repeat; WD repeat.
FT   CHAIN         1    455       Probable cytosolic iron-sulfur protein
FT                                assembly protein 1.
FT                                /FTId=PRO_0000382522.
FT   REPEAT        8     55       WD 1.
FT   REPEAT       59    101       WD 2.
FT   REPEAT      148    187       WD 3.
FT   REPEAT      195    234       WD 4.
FT   REPEAT      266    311       WD 5.
FT   REPEAT      343    382       WD 6.
FT   REPEAT      413    455       WD 7.
SQ   SEQUENCE   455 AA;  50057 MW;  6D6BC3867471446D CRC64;
     MSPKVTITHL SDLTPPSQER TWLTAPHPTL PLVATCSSDK TIRVYSLTNF TLLSTITGGH
     KRSVRTAAWK PHMTGESVLA TGSFDATVGI WRRWDSYGQE GDAGMGMSSG DKQIPTDIST
     AASNGTGTDT ADREEDEEEW RFAVLLDGHD SEVKSVSWSA SGMLLATCSR DKSIWIWEDL
     DDGDNNFETV AVMQEHGGDV KCVSWHPSEE CLASGSYDDT IRLWREDLDD WGQVACIKGH
     GGTVWFLDWE GEETEGNWSG PVADSVSESA LSALQAQWRS QRALSGPRLL SCSDDRTVRV
     WRRQPKESQQ TGPLSSATTG IPSIIRPTGT DEVWEEDAVL PRAHELPVYA VAWSKRTGLV
     ASTGADGRIA LYEERFVTRE QEQEQQADSD AMDTTSGDVL RTEWVLVGVQ DGAHGIYEIN
     HVAWAKRADR RPGGEEEVLV STADDGSVKV WTLTR
//

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