(data stored in ACNUC8465 zone)

SWISSPROT: B6H7B5_PENRW

ID   B6H7B5_PENRW            Unreviewed;       768 AA.
AC   B6H7B5;
DT   16-DEC-2008, integrated into UniProtKB/TrEMBL.
DT   16-DEC-2008, sequence version 1.
DT   07-JUN-2017, entry version 62.
DE   RecName: Full=Ribosome biogenesis protein ERB1 {ECO:0000256|HAMAP-Rule:MF_03027};
DE   AltName: Full=Eukaryotic ribosome biogenesis protein 1 {ECO:0000256|HAMAP-Rule:MF_03027};
GN   Name=ERB1 {ECO:0000256|HAMAP-Rule:MF_03027};
GN   ORFNames=Pc16g02320 {ECO:0000313|EMBL:CAP92902.1}, PCH_Pc16g02320
GN   {ECO:0000313|EMBL:CAP92902.1};
OS   Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 /
OS   Wisconsin 54-1255) (Penicillium chrysogenum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC   Penicillium chrysogenum species complex.
OX   NCBI_TaxID=500485 {ECO:0000313|EMBL:CAP92902.1, ECO:0000313|Proteomes:UP000000724};
RN   [1] {ECO:0000313|EMBL:CAP92902.1, ECO:0000313|Proteomes:UP000000724}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255
RC   {ECO:0000313|Proteomes:UP000000724};
RX   PubMed=18820685; DOI=10.1038/nbt.1498;
RA   van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA   Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA   Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA   Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A.,
RA   van der Klei I.J., van Peij N.N.M.E., Veenhuis M., von Doehren H.,
RA   Wagner C., Wortman J.R., Bovenberg R.A.L.;
RT   "Genome sequencing and analysis of the filamentous fungus Penicillium
RT   chrysogenum.";
RL   Nat. Biotechnol. 26:1161-1168(2008).
CC   -!- FUNCTION: Component of the NOP7 complex, which is required for
CC       maturation of the 25S and 5.8S ribosomal RNAs and formation of the
CC       60S ribosome. {ECO:0000256|HAMAP-Rule:MF_03027}.
CC   -!- SUBUNIT: Component of the NOP7 complex, composed of ERB1, NOP7 and
CC       YTM1. Within the NOP7 complex ERB1 appears to interact directly
CC       with NOP7 and YTM1. The NOP7 complex also associates with the 66S
CC       pre-ribosome. {ECO:0000256|HAMAP-Rule:MF_03027}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000256|HAMAP-
CC       Rule:MF_03027}. Nucleus, nucleoplasm {ECO:0000256|HAMAP-
CC       Rule:MF_03027}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleoplasm
CC       {ECO:0000256|SAAS:SAAS00535448}.
CC   -!- SIMILARITY: Belongs to the WD repeat BOP1/ERB1 family.
CC       {ECO:0000256|HAMAP-Rule:MF_03027, ECO:0000256|SAAS:SAAS00535441}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AM920431; CAP92902.1; -; Genomic_DNA.
DR   RefSeq; XP_002560604.1; XM_002560558.1.
DR   ProteinModelPortal; B6H7B5; -.
DR   STRING; 500485.XP_002560604.1; -.
DR   EnsemblFungi; CAP92902; CAP92902; PCH_Pc16g02320.
DR   GeneID; 8306835; -.
DR   KEGG; pcs:Pc16g02320; -.
DR   eggNOG; KOG0650; Eukaryota.
DR   eggNOG; ENOG410XRBX; LUCA.
DR   HOGENOM; HOG000029368; -.
DR   KO; K14824; -.
DR   OMA; SHGMVYN; -.
DR   OrthoDB; EOG092C1381; -.
DR   BioCyc; PCHR:PC16G02320-MONOMER; -.
DR   Proteomes; UP000000724; Contig Pc00c16.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0030687; C:preribosome, large subunit precursor; IEA:UniProtKB-HAMAP.
DR   GO; GO:0043021; F:ribonucleoprotein complex binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0000466; P:maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-HAMAP.
DR   GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:UniProtKB-HAMAP.
DR   Gene3D; 2.130.10.10; -; 2.
DR   HAMAP; MF_03027; BOP1; 1.
DR   InterPro; IPR028598; BOP1/Erb1.
DR   InterPro; IPR012953; BOP1_N_dom.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR017986; WD40_repeat_dom.
DR   PANTHER; PTHR17605; PTHR17605; 1.
DR   Pfam; PF08145; BOP1NT; 1.
DR   Pfam; PF00400; WD40; 3.
DR   SMART; SM01035; BOP1NT; 1.
DR   SMART; SM00320; WD40; 4.
DR   SUPFAM; SSF50978; SSF50978; 2.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 2.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE   3: Inferred from homology;
DR   PRODOM; B6H7B5.
DR   SWISS-2DPAGE; B6H7B5.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000724};
KW   Nucleus {ECO:0000256|HAMAP-Rule:MF_03027,
KW   ECO:0000256|SAAS:SAAS00001995};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000724};
KW   Repeat {ECO:0000256|SAAS:SAAS00051391};
KW   Ribosome biogenesis {ECO:0000256|HAMAP-Rule:MF_03027,
KW   ECO:0000256|SAAS:SAAS00001991};
KW   rRNA processing {ECO:0000256|HAMAP-Rule:MF_03027,
KW   ECO:0000256|SAAS:SAAS00001989};
KW   WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221,
KW   ECO:0000256|SAAS:SAAS00001990}.
FT   REPEAT      404    445       WD. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00221}.
FT   DOMAIN      404    445       WD_REPEATS_REGION. {ECO:0000259|PROSITE:
FT                                PS50294}.
FT   DOMAIN      679    768       WD_REPEATS_REGION. {ECO:0000259|PROSITE:
FT                                PS50294}.
FT   REPEAT      743    768       WD. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00221}.
SQ   SEQUENCE   768 AA;  85870 MW;  48CC9F16F647A282 CRC64;
     MNPKAASKKR KAVTRDVEEE AGVFSGDELS KGNLDGALSD NSKDLSDSED DESDSEVELV
     DDFSDSEDGE EELDSDEIPS DTEEVKPTAG DPNFRIVKDA NGNDRYLWDE IHPDDNSELS
     EVDENANTIG DIPLKFYDEY PHIGYDINGK KIMRPAKGEA LDALLDSIEI PKGWTGLTDP
     KTGKPLNLSQ EELELLRKVQ MNEVPSEGYD PYEPLVEWFS SEKEIMPLSA APEPKRRFVP
     SKHEQKRVMK LVKAIREGRI LPYKAPEERE DKEEELINYD LWADEAERPD HVMHIPAPKL
     PPPGYEESYH PPPEYLPDSK ERKAWEQTDP EDREKDFLPN DFGSLRKVPG YDNFVQEKFE
     RCLDLYLAPR VRRSKLNIDP ESLLPKLPSP EELKPFPTAC ATVFRGHKGR VRSVNVDPTG
     IWLATGGDDG TVRVWELLTG RQLWSAKLSD DEAVNTVRWR PGKDAVVLAA TAGDDIFLAV
     PPIVDPEIEK ASLDLLDAGW GFAASRPAPS ASEDGKKNAP PTWIRPEAAL VDAGVCVVIP
     LRYVPKTISW HRRGDYFVTV CSGASTPASV AISIHTVSKH LTQFPFRRRL KGGGPPQTAH
     FHPSKPILFV ANQRSIRAYD LSRQLLVKIL QPGARWISSF DIHPTSSSAS GGDNIIVGSY
     DRRLLWHDLD LSQRPYKTLR YHRKAIRAVK FHPSGRYPLF ADASDDGSLQ IFHGSVTGDM
     LSNATIVPLK VLKGHKITGE LGVLDIDWHP REAWAVSAGA DGTCRLWM
//

If you have problems or comments...

PBIL Back to PBIL home page