(data stored in ACNUC8465 zone)

SWISSPROT: UTP25_PENRW

ID   UTP25_PENRW             Reviewed;         715 AA.
AC   B6H768;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 1.
DT   07-JUN-2017, entry version 47.
DE   RecName: Full=U3 small nucleolar RNA-associated protein 25;
DE            Short=U3 snoRNA-associated protein 25;
DE   AltName: Full=U three protein 25;
GN   Name=utp25; ORFNames=Pc16g02470;
OS   Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 /
OS   Wisconsin 54-1255) (Penicillium chrysogenum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC   Penicillium chrysogenum species complex.
OX   NCBI_TaxID=500485;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255;
RX   PubMed=18820685; DOI=10.1038/nbt.1498;
RA   van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA   Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA   Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA   Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A.,
RA   van der Klei I.J., van Peij N.N.M.E., Veenhuis M., von Doehren H.,
RA   Wagner C., Wortman J.R., Bovenberg R.A.L.;
RT   "Genome sequencing and analysis of the filamentous fungus Penicillium
RT   chrysogenum.";
RL   Nat. Biotechnol. 26:1161-1168(2008).
CC   -!- FUNCTION: DEAD-box RNA helicase-like protein required for pre-18S
CC       rRNA processing, specifically at sites A0, A1, and A2.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of the ribosomal small subunit (SSU) processome
CC       composed of at least 40 protein subunits and snoRNA U3.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UTP25 family. {ECO:0000305}.
DR   EMBL; AM920431; CAP92917.1; -; Genomic_DNA.
DR   RefSeq; XP_002560619.1; XM_002560573.1.
DR   STRING; 500485.XP_002560619.1; -.
DR   EnsemblFungi; CAP92917; CAP92917; PCH_Pc16g02470.
DR   GeneID; 8307028; -.
DR   KEGG; pcs:Pc16g02470; -.
DR   eggNOG; KOG2340; Eukaryota.
DR   eggNOG; ENOG410XP00; LUCA.
DR   HOGENOM; HOG000208576; -.
DR   KO; K14774; -.
DR   OMA; ERAHHFR; -.
DR   OrthoDB; EOG092C1Z4A; -.
DR   BioCyc; PCHR:PC16G02470-MONOMER; -.
DR   Proteomes; UP000000724; Contig Pc00c16.
DR   GO; GO:0030529; C:intracellular ribonucleoprotein complex; IEA:UniProtKB-KW.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   InterPro; IPR010678; Digest_organ_expansion_fac-prd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR12933; PTHR12933; 1.
DR   Pfam; PF06862; UTP25; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
PE   3: Inferred from homology;
DR   PRODOM; B6H768.
DR   SWISS-2DPAGE; B6H768.
KW   Complete proteome; Nucleus; Reference proteome; Ribonucleoprotein;
KW   Ribosome biogenesis; rRNA processing.
FT   CHAIN         1    715       U3 small nucleolar RNA-associated protein
FT                                25.
FT                                /FTId=PRO_0000408129.
FT   COMPBIAS      6     31       Gly-rich.
SQ   SEQUENCE   715 AA;  80082 MW;  FAA9E04AB80781B8 CRC64;
     MPAPRGSGSF RGARGRGGRG RGRGRGRGGQ GRNSFATSRL NESDTRSDDS SGGEDDASEQ
     SQEELDDDTL MDEGSSSDEE DENTERPYNE LLQLLQPNES SGPARKKRKI ATDPNAEVQI
     AQPAEEPEQG DDDLEAQAPS DDEEEEADED EDPTAPFEKH FDLRDSADLT KQIEPIQSNK
     WASVKKEVDG LRLVHTVPDT GANSAPILPP LKSTTNIKLK QKLKSRAAEI LPKITGQAQI
     IAPYVFNYQD VLYGARTTSN ANEIRDIMAL HSVNHLLKTR DQVLKNNARL AKDPDTDIEC
     RDQGFTRPKV LYILPTRQAC VKVLDAITRI YQPEQQENKK RFTDSFSAPN DDSWEHKTED
     FRELFGGNDD DMFRLGLKFT RKTVKYFAQF YSSDIILASP LGLRTIMDQS DAKKRDHDFL
     SSIELVVVDH ADALLMQNWD HVDYIFQHLN LQPKQAHGCD FGRVRNWYLD NQARHVRQTV
     VVSSYITPEI NALFSSQMQN ASGRLKATPT YAGAITELPL AVPVKQTFTR IDSTSPIKDP
     DARFKHFTTT ILSTLVKNIT HGRGKGGAGT LIFIPSYLDF VRVRNHFATS TQTTNVSFGA
     ISEYTESKEA NRARSHFMSG RHSVLLYTER AHHFRRYQVR GVKRVVMYGL PDNAMFYGEI
     VGFLGLDPAA LIEAAEGGVR ALFSKWDALK LERVVGTSRT GNMLREKGGD TFTFV
//

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