(data stored in ACNUC8465 zone)

SWISSPROT: C5DC68_LACTC

ID   C5DC68_LACTC            Unreviewed;       652 AA.
AC   C5DC68;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   11-DEC-2019, entry version 60.
DE   SubName: Full=KLTH0B00440p {ECO:0000313|EMBL:CAR21378.1};
GN   OrderedLocusNames=KLTH0B00440g {ECO:0000313|EMBL:CAR21378.1};
OS   Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS   (Yeast) (Kluyveromyces thermotolerans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=559295 {ECO:0000313|EMBL:CAR21378.1, ECO:0000313|Proteomes:UP000002036};
RN   [1] {ECO:0000313|EMBL:CAR21378.1, ECO:0000313|Proteomes:UP000002036}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284
RC   {ECO:0000313|Proteomes:UP000002036};
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA   Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA   Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA   Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA   Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA   Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA   Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA   Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA   Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
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DR   EMBL; CU928166; CAR21378.1; -; Genomic_DNA.
DR   RefSeq; XP_002551817.1; XM_002551771.1.
DR   STRING; 381046.XP_002551817.1; -.
DR   EnsemblFungi; CAR21378; CAR21378; KLTH0B00440g.
DR   GeneID; 8290636; -.
DR   KEGG; lth:KLTH0B00440g; -.
DR   HOGENOM; HOG000000829; -.
DR   InParanoid; C5DC68; -.
DR   KO; K03441; -.
DR   OMA; YPEDLHP; -.
DR   OrthoDB; 1246320at2759; -.
DR   Proteomes; UP000002036; Chromosome B.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015267; F:channel activity; IEA:InterPro.
DR   CDD; cd00333; MIP; 1.
DR   Gene3D; 1.20.1080.10; -; 1.
DR   InterPro; IPR023271; Aquaporin-like.
DR   InterPro; IPR000425; MIP.
DR   InterPro; IPR022357; MIP_CS.
DR   Pfam; PF00230; MIP; 1.
DR   PRINTS; PR00783; MINTRINSICP.
DR   SUPFAM; SSF81338; SSF81338; 1.
DR   TIGRFAMs; TIGR00861; MIP; 1.
DR   PROSITE; PS00221; MIP; 1.
PE   4: Predicted;
DR   PRODOM; C5DC68.
DR   SWISS-2DPAGE; C5DC68.
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002036};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        356..378
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        390..412
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        433..453
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        488..507
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        519..536
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1..121
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          187..213
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          240..271
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          623..652
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..25
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        26..41
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        74..88
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        187..204
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        240..270
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        633..652
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   652 AA;  70910 MW;  F031DD739C5E8C8E CRC64;
     MVGESIMPSS SSSSSISSSS SDVPRATREQ RGREGETEQV KWSGNLKDSS QKTKRGDRTS
     VDVGVARGVS SGRKATHTEG TKNVLSRLTP LNKPAAEDAQ PRHQKRHPVG TAFSSPNLKS
     LNTPLSREQA RLMEYYLSTA VPRSNNNYVD PLYRHLNPSV GSTKSRPVWS LNQPLPHVLD
     HSLAEKMLKK NTDVKSRASS RPESREMSRA GSLASMNDWK KLIGRSGSWR KLNDVEAQIP
     GATKNSGLTR NRKHSQSQIE FANNQRRAHH AASFQLGDES CTPSLRGEDV PAQIQNQKQA
     GTAPTAEELL EKRFRSSLDG ATPLDGGRLG TGDSESEQLA FTNYWAKIRY RLREPFAEFL
     GTLILVIFGV GGNLQATVTN GSGGSYESLS FAWGFGCMLG VYVAGGVSGG HINPAVTISM
     AIFRKFPWKK VPVYIFAQIV GAFFGGAMAY GYFWSSITEF EGGTHIRTAA SGACLFTNPK
     SYVTWRNAFF DEFIGASMLV GCLMALLDDS NSPPTNGMTA LIVGFLVAAI GMALGYQTSF
     TINPARDLGP RIFASMIGYG PHAFHLTHWW WTWGAWGGPI AGGIAGALVY DIFIFTGCES
     PVNYPDNGYI EHRVSKILHA EFHPHDSPKS SEVVVEEGSN SKDGSTKSNS AH
//

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