(data stored in ACNUC8465 zone)

SWISSPROT: C5DCL3_LACTC

ID   C5DCL3_LACTC            Unreviewed;       153 AA.
AC   C5DCL3;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   16-JAN-2019, entry version 55.
DE   RecName: Full=Nucleoside diphosphate kinase {ECO:0000256|RuleBase:RU004013};
DE            EC=2.7.4.6 {ECO:0000256|RuleBase:RU004013};
GN   OrderedLocusNames=KLTH0B04004g {ECO:0000313|EMBL:CAR21524.1};
OS   Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS   (Yeast) (Kluyveromyces thermotolerans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=559295 {ECO:0000313|EMBL:CAR21524.1, ECO:0000313|Proteomes:UP000002036};
RN   [1] {ECO:0000313|EMBL:CAR21524.1, ECO:0000313|Proteomes:UP000002036}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284
RC   {ECO:0000313|Proteomes:UP000002036};
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P.,
RA   Jubin C., Poulain J., Barbe V., Segurens B., Artiguenave F.,
RA   Anthouard V., Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R.,
RA   Durrens P., Jean G., Marck C., Martin T., Nikolski M., Rolland T.,
RA   Seret M.-L., Casaregola S., Despons L., Fairhead C., Fischer G.,
RA   Lafontaine I., Leh V., Lemaire M., de Montigny J., Neuveglise C.,
RA   Thierry A., Blanc-Lenfle I., Bleykasten C., Diffels J., Fritsch E.,
RA   Frangeul L., Goeffon A., Jauniaux N., Kachouri-Lafond R., Payen C.,
RA   Potier S., Pribylova L., Ozanne C., Richard G.-F., Sacerdot C.,
RA   Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-
CC         deoxyribonucleoside 5'-triphosphate + ADP; Xref=Rhea:RHEA:44640,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:61560, ChEBI:CHEBI:73316,
CC         ChEBI:CHEBI:456216; EC=2.7.4.6;
CC         Evidence={ECO:0000256|RuleBase:RU004013};
CC   -!- SIMILARITY: Belongs to the NDK family.
CC       {ECO:0000256|RuleBase:RU004011}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CU928166; CAR21524.1; -; Genomic_DNA.
DR   RefSeq; XP_002551962.1; XM_002551916.1.
DR   STRING; 381046.XP_002551962.1; -.
DR   EnsemblFungi; CAR21524; CAR21524; KLTH0B04004g.
DR   GeneID; 8290797; -.
DR   KEGG; lth:KLTH0B04004g; -.
DR   HOGENOM; HOG000224564; -.
DR   InParanoid; C5DCL3; -.
DR   KO; K00940; -.
DR   OMA; KIVAMKM; -.
DR   OrthoDB; 1334716at2759; -.
DR   Proteomes; UP000002036; Chromosome B.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004550; F:nucleoside diphosphate kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006241; P:CTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0006183; P:GTP biosynthetic process; IEA:InterPro.
DR   GO; GO:0006228; P:UTP biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.30.70.141; -; 1.
DR   HAMAP; MF_00451; NDP_kinase; 1.
DR   InterPro; IPR034907; NDK-like_dom.
DR   InterPro; IPR036850; NDK-like_dom_sf.
DR   InterPro; IPR001564; Nucleoside_diP_kinase.
DR   InterPro; IPR023005; Nucleoside_diP_kinase_AS.
DR   Pfam; PF00334; NDK; 1.
DR   PRINTS; PR01243; NUCDPKINASE.
DR   SMART; SM00562; NDK; 1.
DR   SUPFAM; SSF54919; SSF54919; 1.
DR   PROSITE; PS00469; NDP_KINASES; 1.
PE   3: Inferred from homology;
DR   PRODOM; C5DCL3.
DR   SWISS-2DPAGE; C5DCL3.
KW   ATP-binding {ECO:0000256|RuleBase:RU004013};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002036};
KW   Kinase {ECO:0000256|RuleBase:RU004013};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU004013};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002036};
KW   Transferase {ECO:0000256|RuleBase:RU004013}.
FT   DOMAIN        5    142       NDK. {ECO:0000259|SMART:SM00562}.
SQ   SEQUENCE   153 AA;  17070 MW;  4936F80AF7C40AC6 CRC64;
     MSSQTERTFI AIKPDGVQRG LVAKILARFE DRGFKLVAVK LLRPSQELLR QHYAEHVDKP
     FFPKMSAFMS SGPVLATVWE GKDAVRQGRV ILGATNPLNS APGTIRGDFA IDMGRNVCHG
     SDSVESAQRE IALWFQPEEL VEWTPAQAAW VYE
//

If you have problems or comments...

PBIL Back to PBIL home page