(data stored in ACNUC8465 zone)

SWISSPROT: C5DD27_LACTC

ID   C5DD27_LACTC            Unreviewed;       332 AA.
AC   C5DD27;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   08-MAY-2019, entry version 68.
DE   SubName: Full=KLTH0B07788p {ECO:0000313|EMBL:CAR21688.1};
GN   OrderedLocusNames=KLTH0B07788g {ECO:0000313|EMBL:CAR21688.1};
OS   Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS   (Yeast) (Kluyveromyces thermotolerans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=559295 {ECO:0000313|EMBL:CAR21688.1, ECO:0000313|Proteomes:UP000002036};
RN   [1] {ECO:0000313|EMBL:CAR21688.1, ECO:0000313|Proteomes:UP000002036}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284
RC   {ECO:0000313|Proteomes:UP000002036};
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P.,
RA   Jubin C., Poulain J., Barbe V., Segurens B., Artiguenave F.,
RA   Anthouard V., Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R.,
RA   Durrens P., Jean G., Marck C., Martin T., Nikolski M., Rolland T.,
RA   Seret M.-L., Casaregola S., Despons L., Fairhead C., Fischer G.,
RA   Lafontaine I., Leh V., Lemaire M., de Montigny J., Neuveglise C.,
RA   Thierry A., Blanc-Lenfle I., Bleykasten C., Diffels J., Fritsch E.,
RA   Frangeul L., Goeffon A., Jauniaux N., Kachouri-Lafond R., Payen C.,
RA   Potier S., Pribylova L., Ozanne C., Richard G.-F., Sacerdot C.,
RA   Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein]
CC         + phosphate; Xref=Rhea:RHEA:10684, Rhea:RHEA-COMP:10136,
CC         Rhea:RHEA-COMP:10137, ChEBI:CHEBI:15377, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:46858, ChEBI:CHEBI:82620; EC=3.1.3.48;
CC         Evidence={ECO:0000256|SAAS:SAAS01128831};
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CU928166; CAR21688.1; -; Genomic_DNA.
DR   RefSeq; XP_002552126.1; XM_002552080.1.
DR   STRING; 381046.XP_002552126.1; -.
DR   EnsemblFungi; CAR21688; CAR21688; KLTH0B07788g.
DR   GeneID; 8290966; -.
DR   KEGG; lth:KLTH0B07788g; -.
DR   HOGENOM; HOG000243992; -.
DR   InParanoid; C5DD27; -.
DR   KO; K01104; -.
DR   OMA; KMVKCGD; -.
DR   OrthoDB; 411281at2759; -.
DR   Proteomes; UP000002036; Chromosome B.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.90.190.10; -; 1.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   InterPro; IPR016277; Ptp1.
DR   InterPro; IPR000242; PTPase_domain.
DR   InterPro; IPR016130; Tyr_Pase_AS.
DR   InterPro; IPR003595; Tyr_Pase_cat.
DR   InterPro; IPR000387; TYR_PHOSPHATASE_dom.
DR   Pfam; PF00102; Y_phosphatase; 1.
DR   PIRSF; PIRSF000938; PTPN1_yeast; 1.
DR   PRINTS; PR00700; PRTYPHPHTASE.
DR   SMART; SM00194; PTPc; 1.
DR   SMART; SM00404; PTPc_motif; 1.
DR   SUPFAM; SSF52799; SSF52799; 1.
DR   PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR   PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR   PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 1.
PE   4: Predicted;
DR   PRODOM; C5DD27.
DR   SWISS-2DPAGE; C5DD27.
KW   Complete proteome {ECO:0000313|Proteomes:UP000002036};
KW   Hydrolase {ECO:0000256|PROSITE-ProRule:PRU00160,
KW   ECO:0000256|SAAS:SAAS01031440};
KW   Protein phosphatase {ECO:0000256|SAAS:SAAS01031415};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002036}.
FT   DOMAIN       17    323       Tyrosine-protein phosphatase.
FT                                {ECO:0000259|PROSITE:PS50055}.
FT   DOMAIN      229    314       TYR_PHOSPHATASE_2. {ECO:0000259|PROSITE:
FT                                PS50056}.
FT   ACT_SITE    255    255       Phosphocysteine intermediate.
FT                                {ECO:0000256|PROSITE-ProRule:PRU00160}.
SQ   SEQUENCE   332 AA;  38126 MW;  3E547D79E671985B CRC64;
     MASETVPWYL KQSAQELVSK FRFIQHQEDL RLRDATLNPA KSRWSLGSSV DESNDDRNRY
     VNIMPYERNR VKLRTQAGND YINASYVKVQ VPGQSVRPGH YIATQGPTQN SWPQFWQMCY
     QQCTGSDIVI AMVTPLVEGG RQKCFEYWPH DAAAPLKIPR TQSSSCSASG PESSCTTFDV
     DLEVHFQCSE RENDYTLSTL ELAPADPAFP KKTVHHFYFD RWRDMSKPDE IVPILKLSRH
     AHSLNSSENP MVVHCSAGVG RTGTFITLDH LFHDTLDFTA AQPVQDYSHD LVEQIVLQLR
     TQRLKMVQMV DQFLFIYHAA RYVFDLARTR DQ
//

If you have problems or comments...

PBIL Back to PBIL home page