(data stored in ACNUC6288 zone)

SWISSPROT: HUT1_DEBHA

ID   HUT1_DEBHA              Reviewed;         354 AA.
AC   Q6BMV3; B5RU80;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 2.
DT   08-MAY-2019, entry version 73.
DE   RecName: Full=UDP-galactose transporter homolog 1;
GN   Name=HUT1; OrderedLocusNames=DEHA2F02376g;
OS   Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC
OS   0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
OC   Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX   NCBI_TaxID=284592;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S.,
RA   Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E.,
RA   Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V.,
RA   Barnay S., Blanchin S., Beckerich J.-M., Beyne E., Bleykasten C.,
RA   Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A.,
RA   Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A.,
RA   Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R.,
RA   Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H.,
RA   Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O.,
RA   Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A.,
RA   Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B.,
RA   Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A.,
RA   Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J.,
RA   Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: May be involved in specific transport of UDP-Gal from
CC       the cytosol to the Golgi lumen. Involved in the maintenance of
CC       optimal conditions for the folding of secretory pathway proteins
CC       in the endoplasmic reticulum (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the nucleotide-sugar transporter family.
CC       SLC35B subfamily. {ECO:0000305}.
DR   EMBL; CR382138; CAR66257.1; -; Genomic_DNA.
DR   RefSeq; XP_002770726.1; XM_002770680.1.
DR   STRING; 4959.XP_002770726.1; -.
DR   EnsemblFungi; CAR66257; CAR66257; DEHA2F02376g.
DR   GeneID; 8998860; -.
DR   KEGG; dha:DEHA2F02376g; -.
DR   HOGENOM; HOG000091197; -.
DR   InParanoid; Q6BMV3; -.
DR   KO; K15275; -.
DR   OMA; CGAIGQV; -.
DR   OrthoDB; 1220063at2759; -.
DR   Proteomes; UP000000599; Chromosome F.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   GO; GO:0072334; P:UDP-galactose transmembrane transport; IEA:EnsemblFungi.
DR   GO; GO:0015786; P:UDP-glucose transmembrane transport; IEA:EnsemblFungi.
DR   InterPro; IPR013657; UAA.
DR   Pfam; PF08449; UAA; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q6BMV3.
DR   SWISS-2DPAGE; Q6BMV3.
KW   Complete proteome; Endoplasmic reticulum; Glycoprotein; Membrane;
KW   Reference proteome; Sugar transport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN         1    354       UDP-galactose transporter homolog 1.
FT                                /FTId=PRO_0000213408.
FT   TRANSMEM      6     26       Helical. {ECO:0000255}.
FT   TRANSMEM     54     74       Helical. {ECO:0000255}.
FT   TRANSMEM     95    112       Helical. {ECO:0000255}.
FT   TRANSMEM    123    143       Helical. {ECO:0000255}.
FT   TRANSMEM    148    168       Helical. {ECO:0000255}.
FT   TRANSMEM    227    247       Helical. {ECO:0000255}.
FT   TRANSMEM    268    288       Helical. {ECO:0000255}.
FT   TRANSMEM    295    317       Helical. {ECO:0000255}.
FT   TRANSMEM    321    340       Helical. {ECO:0000255}.
FT   CARBOHYD    202    202       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
SQ   SEQUENCE   354 AA;  38849 MW;  35328AE734A30D46 CRC64;
     MKKEGGGSII TLAACILGLY ASFLTWSVLQ ERISTKPYGS NPDTGSPDFF KAPLVINIIQ
     AFFASIVGLI YSVVSSRSNP LSIFTQNEKP VALKFFKSFV IISLTSSLSS PLGYESLKHV
     DYLAYLLAKS CKLIPVMLVH FVLYRTKFPL YKCMVAGSVT VGVIIFTLSH SSTKSKADIS
     DGKTALGMAQ LIGSMLLDGL TNSTQDQLFK LRGTSPSNKH TKLTGAYLMC ILNAFIFINT
     LAYALIFKYQ SEITYTVNFV HHYPQVMMNI LEFAILGSVG QVFVFIILEK FDSLILITST
     VTRKMISMIL SVVLFGHQLN GLQWGGVGLV FGGIGYEALV KMSMNKAPTT KKNQ
//

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