(data stored in ACNUC7421 zone)

SWISSPROT: MRAZ_ECO27

ID   MRAZ_ECO27              Reviewed;         152 AA.
AC   B7UID1;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   08-MAY-2019, entry version 62.
DE   RecName: Full=Transcriptional regulator MraZ;
GN   Name=mraZ {ECO:0000255|HAMAP-Rule:MF_01008};
GN   OrderedLocusNames=E2348C_0086;
OS   Escherichia coli O127:H6 (strain E2348/69 / EPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=574521;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=E2348/69 / EPEC;
RX   PubMed=18952797; DOI=10.1128/JB.01238-08;
RA   Iguchi A., Thomson N.R., Ogura Y., Saunders D., Ooka T.,
RA   Henderson I.R., Harris D., Asadulghani M., Kurokawa K., Dean P.,
RA   Kenny B., Quail M.A., Thurston S., Dougan G., Hayashi T., Parkhill J.,
RA   Frankel G.;
RT   "Complete genome sequence and comparative genome analysis of
RT   enteropathogenic Escherichia coli O127:H6 strain E2348/69.";
RL   J. Bacteriol. 191:347-354(2009).
CC   -!- FUNCTION: Negatively regulates its own expression and that of the
CC       subsequent genes in the proximal part of the division and cell
CC       wall (dcw) gene cluster. Acts by binding directly to DNA. May also
CC       regulate the expression of genes outside the dcw cluster.
CC       {ECO:0000255|HAMAP-Rule:MF_01008}.
CC   -!- SUBUNIT: Forms oligomers. {ECO:0000255|HAMAP-Rule:MF_01008}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid {ECO:0000255|HAMAP-
CC       Rule:MF_01008}.
CC   -!- SIMILARITY: Belongs to the MraZ family. {ECO:0000255|HAMAP-
CC       Rule:MF_01008}.
DR   EMBL; FM180568; CAS07634.1; -; Genomic_DNA.
DR   RefSeq; WP_001339537.1; NC_011601.1.
DR   SMR; B7UID1; -.
DR   EnsemblBacteria; CAS07634; CAS07634; E2348C_0086.
DR   KEGG; ecg:E2348C_0086; -.
DR   KO; K03925; -.
DR   OMA; RGQERCL; -.
DR   BioCyc; ECOL574521:E2348C_RS00445-MONOMER; -.
DR   Proteomes; UP000008205; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-UniRule.
DR   GO; GO:0009295; C:nucleoid; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   CDD; cd16321; MraZ_C; 1.
DR   CDD; cd16320; MraZ_N; 1.
DR   Gene3D; 2.40.330.20; -; 1.
DR   HAMAP; MF_01008; MraZ; 1.
DR   InterPro; IPR003444; MraZ.
DR   InterPro; IPR035644; MraZ_C.
DR   InterPro; IPR020603; MraZ_dom.
DR   InterPro; IPR035642; MraZ_N.
DR   InterPro; IPR038619; MraZ_sf.
DR   InterPro; IPR007159; SpoVT-AbrB_dom.
DR   InterPro; IPR037914; SpoVT-AbrB_sf.
DR   PANTHER; PTHR34701; PTHR34701; 1.
DR   Pfam; PF02381; MraZ; 2.
DR   ProDom; PD006745; MraZ; 1.
DR   SUPFAM; SSF89447; SSF89447; 1.
DR   TIGRFAMs; TIGR00242; TIGR00242; 1.
DR   PROSITE; PS51740; SPOVT_ABRB; 2.
PE   3: Inferred from homology;
DR   PRODOM; B7UID1.
DR   SWISS-2DPAGE; B7UID1.
KW   Complete proteome; Cytoplasm; DNA-binding; Repeat; Repressor;
KW   Transcription; Transcription regulation.
FT   CHAIN         1    152       Transcriptional regulator MraZ.
FT                                /FTId=PRO_1000148854.
FT   DOMAIN        5     52       SpoVT-AbrB 1. {ECO:0000255|PROSITE-
FT                                ProRule:PRU01076}.
FT   DOMAIN       81    124       SpoVT-AbrB 2. {ECO:0000255|PROSITE-
FT                                ProRule:PRU01076}.
SQ   SEQUENCE   152 AA;  17330 MW;  20B6F48FA2EDD5C0 CRC64;
     MFRGATLVNL DSKGRLSVPT RYREQLLENA AGQMVCTIDI HHPCLLLYPL PEWEIIEQKL
     SRLSSTNPVE RRVQRLLLGH ASECQMDGAG RLLIAPVLRQ HAGLTKEVML VGQFNKFELW
     DETTWHQQVK EDIDAEQLAT GDLSERLQDL SL
//

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