(data stored in ACNUC7421 zone)

SWISSPROT: CRL_ECO27

ID   CRL_ECO27               Reviewed;         133 AA.
AC   B7UJC8;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   05-DEC-2018, entry version 53.
DE   RecName: Full=Sigma factor-binding protein Crl {ECO:0000255|HAMAP-Rule:MF_01178};
GN   Name=crl {ECO:0000255|HAMAP-Rule:MF_01178};
GN   OrderedLocusNames=E2348C_0233;
OS   Escherichia coli O127:H6 (strain E2348/69 / EPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=574521;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=E2348/69 / EPEC;
RX   PubMed=18952797; DOI=10.1128/JB.01238-08;
RA   Iguchi A., Thomson N.R., Ogura Y., Saunders D., Ooka T.,
RA   Henderson I.R., Harris D., Asadulghani M., Kurokawa K., Dean P.,
RA   Kenny B., Quail M.A., Thurston S., Dougan G., Hayashi T., Parkhill J.,
RA   Frankel G.;
RT   "Complete genome sequence and comparative genome analysis of
RT   enteropathogenic Escherichia coli O127:H6 strain E2348/69.";
RL   J. Bacteriol. 191:347-354(2009).
CC   -!- FUNCTION: Binds to the sigma-S subunit of RNA polymerase,
CC       activating expression of sigma-S-regulated genes. Stimulates RNA
CC       polymerase holoenzyme formation and may bind to several other
CC       sigma factors, such as sigma-70 and sigma-32. {ECO:0000255|HAMAP-
CC       Rule:MF_01178}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01178}.
CC   -!- SIMILARITY: Belongs to the Crl family. {ECO:0000255|HAMAP-
CC       Rule:MF_01178}.
DR   EMBL; FM180568; CAS07781.1; -; Genomic_DNA.
DR   RefSeq; WP_000174682.1; NC_011601.1.
DR   SMR; B7UJC8; -.
DR   PRIDE; B7UJC8; -.
DR   EnsemblBacteria; CAS07781; CAS07781; E2348C_0233.
DR   KEGG; ecg:E2348C_0233; -.
DR   KO; K11926; -.
DR   OMA; FWGWWLE; -.
DR   BioCyc; ECOL574521:E2348C_RS01235-MONOMER; -.
DR   Proteomes; UP000008205; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.310.230; -; 1.
DR   HAMAP; MF_01178; Crl; 1.
DR   InterPro; IPR009986; Tscrpt_reg_Crl.
DR   InterPro; IPR038208; Tscrpt_reg_Crl_sf.
DR   Pfam; PF07417; Crl; 1.
PE   3: Inferred from homology;
DR   PRODOM; B7UJC8.
DR   SWISS-2DPAGE; B7UJC8.
KW   Activator; Coiled coil; Complete proteome; Cytoplasm; Transcription;
KW   Transcription regulation.
FT   CHAIN         1    133       Sigma factor-binding protein Crl.
FT                                /FTId=PRO_1000164423.
FT   REGION       99    122       Essential for activity.
FT                                {ECO:0000255|HAMAP-Rule:MF_01178}.
FT   COILED       90    116       {ECO:0000255|HAMAP-Rule:MF_01178}.
SQ   SEQUENCE   133 AA;  15599 MW;  E706DB482AF437CC CRC64;
     MTLPSGHPKS RLIKKFTALG PYIREGKCED NRFFFDCLAV CVNVKPAPEV REFWGWWMEL
     EAQESRFTYS YQFGLFDKAG DWTSVPVKDT EVVERLEHTL REFHEKLREL LATLNLKLEP
     ADDFRDEPVK LTA
//

If you have problems or comments...

PBIL Back to PBIL home page