(data stored in ACNUC7421 zone)

SWISSPROT: B7UJJ6_ECO27

ID   B7UJJ6_ECO27            Unreviewed;       255 AA.
AC   B7UJJ6;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   08-MAY-2019, entry version 66.
DE   RecName: Full=Taurine import ATP-binding protein TauB {ECO:0000256|HAMAP-Rule:MF_01714};
DE            EC=7.6.2.7 {ECO:0000256|HAMAP-Rule:MF_01714};
GN   Name=tauB {ECO:0000256|HAMAP-Rule:MF_01714,
GN   ECO:0000313|EMBL:CAS07854.1};
GN   OrderedLocusNames=E2348C_0306 {ECO:0000313|EMBL:CAS07854.1};
OS   Escherichia coli O127:H6 (strain E2348/69 / EPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=574521 {ECO:0000313|EMBL:CAS07854.1, ECO:0000313|Proteomes:UP000008205};
RN   [1] {ECO:0000313|EMBL:CAS07854.1, ECO:0000313|Proteomes:UP000008205}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=E2348/69 / EPEC {ECO:0000313|Proteomes:UP000008205};
RX   PubMed=18952797; DOI=10.1128/JB.01238-08;
RA   Iguchi A., Thomson N.R., Ogura Y., Saunders D., Ooka T.,
RA   Henderson I.R., Harris D., Asadulghani M., Kurokawa K., Dean P.,
RA   Kenny B., Quail M.A., Thurston S., Dougan G., Hayashi T., Parkhill J.,
RA   Frankel G.;
RT   "Complete genome sequence and comparative genome analysis of
RT   enteropathogenic Escherichia coli O127:H6 strain E2348/69.";
RL   J. Bacteriol. 191:347-354(2009).
CC   -!- FUNCTION: Part of the ABC transporter complex TauABC involved in
CC       taurine import. Responsible for energy coupling to the transport
CC       system. {ECO:0000256|HAMAP-Rule:MF_01714}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O + taurine(out) = ADP + H(+) + phosphate +
CC         taurine(in); Xref=Rhea:RHEA:14613, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:456216, ChEBI:CHEBI:507393; EC=7.6.2.7;
CC         Evidence={ECO:0000256|HAMAP-Rule:MF_01714};
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins
CC       (TauB), two transmembrane proteins (TauC) and a solute-binding
CC       protein (TauA). {ECO:0000256|HAMAP-Rule:MF_01714}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC       Rule:MF_01714}; Peripheral membrane protein {ECO:0000256|HAMAP-
CC       Rule:MF_01714}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Taurine
CC       importer (TC 3.A.1.17.1) family. {ECO:0000256|HAMAP-
CC       Rule:MF_01714}.
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DR   EMBL; FM180568; CAS07854.1; -; Genomic_DNA.
DR   RefSeq; WP_000939357.1; NC_011601.1.
DR   EnsemblBacteria; CAS07854; CAS07854; E2348C_0306.
DR   KEGG; ecg:E2348C_0306; -.
DR   KO; K10831; -.
DR   OMA; FENHWPK; -.
DR   BioCyc; ECOL574521:E2348C_RS01610-MONOMER; -.
DR   Proteomes; UP000008205; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0015411; F:taurine-transporting ATPase activity; IEA:UniProtKB-UniRule.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like.
DR   InterPro; IPR017871; ABC_transporter_CS.
DR   InterPro; IPR015859; ABC_transpr_TauD.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR   PROSITE; PS51250; TAUB; 1.
PE   3: Inferred from homology;
DR   PRODOM; B7UJJ6.
DR   SWISS-2DPAGE; B7UJJ6.
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_01714, ECO:0000256|PROSITE-
KW   ProRule:PRU00434};
KW   Cell inner membrane {ECO:0000256|HAMAP-Rule:MF_01714};
KW   Cell membrane {ECO:0000256|HAMAP-Rule:MF_01714};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008205};
KW   Membrane {ECO:0000256|HAMAP-Rule:MF_01714};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01714,
KW   ECO:0000256|PROSITE-ProRule:PRU00434};
KW   Translocase {ECO:0000256|HAMAP-Rule:MF_01714};
KW   Transport {ECO:0000256|HAMAP-Rule:MF_01714}.
FT   DOMAIN        2    229       ABC transporter. {ECO:0000259|PROSITE:
FT                                PS50893}.
FT   DOMAIN      189    255       TAUB. {ECO:0000259|PROSITE:PS51250}.
FT   NP_BIND      34     41       ATP. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00434}.
SQ   SEQUENCE   255 AA;  28200 MW;  D674252562031356 CRC64;
     MLQISHLYAD YGGKPALEDI NLTLESGELL VVLGPSGCGK TTLLNLIAGF VPYQHGSIQL
     AGKGIQGPGA ERGVVFQNEG LLPWRNVKDN VAFGLQLAGV EKMQRLEIAH QMVKKVGLEG
     AEKRYIWQLS GGQRQRVGIA RALAANPQLL LLDEPFGALD AFTRDQMQTL LLKLWQETGK
     QVLLITHDIE EAVFMATELV LLSSGPGRVL ERLQLNFARR FVAGESSRSI KSDPQFIAMR
     EYVLSRVFEQ REAFS
//

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