(data stored in ACNUC7421 zone)

SWISSPROT: IRAP_ECO27

ID   IRAP_ECO27              Reviewed;          86 AA.
AC   B7UJK6;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   05-DEC-2018, entry version 49.
DE   RecName: Full=Anti-adapter protein IraP {ECO:0000255|HAMAP-Rule:MF_01198};
GN   Name=iraP {ECO:0000255|HAMAP-Rule:MF_01198};
GN   OrderedLocusNames=E2348C_0318;
OS   Escherichia coli O127:H6 (strain E2348/69 / EPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=574521;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=E2348/69 / EPEC;
RX   PubMed=18952797; DOI=10.1128/JB.01238-08;
RA   Iguchi A., Thomson N.R., Ogura Y., Saunders D., Ooka T.,
RA   Henderson I.R., Harris D., Asadulghani M., Kurokawa K., Dean P.,
RA   Kenny B., Quail M.A., Thurston S., Dougan G., Hayashi T., Parkhill J.,
RA   Frankel G.;
RT   "Complete genome sequence and comparative genome analysis of
RT   enteropathogenic Escherichia coli O127:H6 strain E2348/69.";
RL   J. Bacteriol. 191:347-354(2009).
CC   -!- FUNCTION: Inhibits RpoS proteolysis by regulating RssB activity,
CC       thereby increasing the stability of the sigma stress factor RpoS
CC       especially during phosphate starvation, but also in stationary
CC       phase and during nitrogen starvation. Its effect on RpoS stability
CC       is due to its interaction with RssB, which probably blocks the
CC       interaction of RssB with RpoS, and the consequent delivery of the
CC       RssB-RpoS complex to the ClpXP protein degradation pathway.
CC       {ECO:0000255|HAMAP-Rule:MF_01198}.
CC   -!- SUBUNIT: Interacts with RssB. {ECO:0000255|HAMAP-Rule:MF_01198}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01198}.
CC   -!- SIMILARITY: Belongs to the IraP family. {ECO:0000255|HAMAP-
CC       Rule:MF_01198}.
DR   EMBL; FM180568; CAS07866.1; -; Genomic_DNA.
DR   RefSeq; WP_000792973.1; NC_011601.1.
DR   SMR; B7UJK6; -.
DR   EnsemblBacteria; CAS07866; CAS07866; E2348C_0318.
DR   KEGG; ecg:E2348C_0318; -.
DR   OMA; IDTAMIH; -.
DR   BioCyc; ECOL574521:E2348C_RS01675-MONOMER; -.
DR   Proteomes; UP000008205; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009267; P:cellular response to starvation; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01198; Anti_adapt_IraP; 1.
DR   InterPro; IPR019732; SigmaS_Anti-adapt_IraP.
DR   Pfam; PF10796; Anti-adapt_IraP; 1.
PE   3: Inferred from homology;
DR   PRODOM; B7UJK6.
DR   SWISS-2DPAGE; B7UJK6.
KW   Coiled coil; Complete proteome; Cytoplasm; Stress response.
FT   CHAIN         1     86       Anti-adapter protein IraP.
FT                                /FTId=PRO_1000164549.
FT   COILED        1     36       {ECO:0000255|HAMAP-Rule:MF_01198}.
SQ   SEQUENCE   86 AA;  9965 MW;  1C2EE018A8816BEE CRC64;
     MKNLIAELLF KLAQKEEESK ELCAQVEALE IIVTAMLRNM AQNDQQRLID QVEGALYEVK
     PDASIPDDDT ELLRDYVKKL LRHPRQ
//

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