(data stored in ACNUC7421 zone)

SWISSPROT: ACPH_ECO27

ID   ACPH_ECO27              Reviewed;         193 AA.
AC   B7UJM7;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   05-DEC-2018, entry version 49.
DE   RecName: Full=Acyl carrier protein phosphodiesterase {ECO:0000255|HAMAP-Rule:MF_01950};
DE            Short=ACP phosphodiesterase {ECO:0000255|HAMAP-Rule:MF_01950};
DE            EC=3.1.4.14 {ECO:0000255|HAMAP-Rule:MF_01950};
GN   Name=acpH {ECO:0000255|HAMAP-Rule:MF_01950};
GN   OrderedLocusNames=E2348C_0339;
OS   Escherichia coli O127:H6 (strain E2348/69 / EPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=574521;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=E2348/69 / EPEC;
RX   PubMed=18952797; DOI=10.1128/JB.01238-08;
RA   Iguchi A., Thomson N.R., Ogura Y., Saunders D., Ooka T.,
RA   Henderson I.R., Harris D., Asadulghani M., Kurokawa K., Dean P.,
RA   Kenny B., Quail M.A., Thurston S., Dougan G., Hayashi T., Parkhill J.,
RA   Frankel G.;
RT   "Complete genome sequence and comparative genome analysis of
RT   enteropathogenic Escherichia coli O127:H6 strain E2348/69.";
RL   J. Bacteriol. 191:347-354(2009).
CC   -!- FUNCTION: Converts holo-ACP to apo-ACP by hydrolytic cleavage of
CC       the phosphopantetheine prosthetic group from ACP.
CC       {ECO:0000255|HAMAP-Rule:MF_01950}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + holo-[ACP] = apo-[ACP] + D-pantetheine 4'-phosphate
CC         + H(+); Xref=Rhea:RHEA:20537, Rhea:RHEA-COMP:9685, Rhea:RHEA-
CC         COMP:9690, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:29999, ChEBI:CHEBI:61723, ChEBI:CHEBI:64479;
CC         EC=3.1.4.14; Evidence={ECO:0000255|HAMAP-Rule:MF_01950};
CC   -!- SIMILARITY: Belongs to the AcpH family. {ECO:0000255|HAMAP-
CC       Rule:MF_01950}.
DR   EMBL; FM180568; CAS07887.1; -; Genomic_DNA.
DR   RefSeq; WP_001009870.1; NC_011601.1.
DR   EnsemblBacteria; CAS07887; CAS07887; E2348C_0339.
DR   KEGG; ecg:E2348C_0339; -.
DR   KO; K08682; -.
DR   OMA; MNFLAHI; -.
DR   BioCyc; ECOL574521:E2348C_RS01785-MONOMER; -.
DR   Proteomes; UP000008205; Chromosome.
DR   GO; GO:0008770; F:[acyl-carrier-protein] phosphodiesterase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01950; AcpH; 1.
DR   InterPro; IPR007431; ACP_PD.
DR   InterPro; IPR023491; ACP_phosphodiesterase_gpbac.
DR   PANTHER; PTHR38764; PTHR38764; 1.
DR   Pfam; PF04336; ACP_PD; 1.
DR   PIRSF; PIRSF011489; DUF479; 1.
PE   3: Inferred from homology;
DR   PRODOM; B7UJM7.
DR   SWISS-2DPAGE; B7UJM7.
KW   Complete proteome; Fatty acid biosynthesis; Fatty acid metabolism;
KW   Hydrolase; Lipid biosynthesis; Lipid metabolism.
FT   CHAIN         1    193       Acyl carrier protein phosphodiesterase.
FT                                /FTId=PRO_1000188797.
SQ   SEQUENCE   193 AA;  23021 MW;  AB5716174B14E9F7 CRC64;
     MNFLAHLHLA HLAESSLSGN LLADFVRGNP EESFPPDVVA GIHMHRRIDV LTDNLPEVRE
     AREWFRNETR RVAPITLDVM WDHFLSRHWS QLSPDFPLQE FTCYAREQVM TILPDSPPRF
     INLNNYLWSE QWLVRYRDMD FIQSVLNGMA SRRPRLDALR DSWYDLDAHY DALETRFWQF
     YPRMMEQASR KAL
//

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