(data stored in ACNUC7421 zone)

SWISSPROT: B7UKF8_ECO27

ID   B7UKF8_ECO27            Unreviewed;       558 AA.
AC   B7UKF8;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   08-MAY-2019, entry version 67.
DE   SubName: Full=Predicted transporter with NAD(P)-binding Rossmann-fold domain {ECO:0000313|EMBL:CAS07961.1};
GN   Name=ybaL {ECO:0000313|EMBL:CAS07961.1};
GN   OrderedLocusNames=E2348C_0413 {ECO:0000313|EMBL:CAS07961.1};
OS   Escherichia coli O127:H6 (strain E2348/69 / EPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=574521 {ECO:0000313|EMBL:CAS07961.1, ECO:0000313|Proteomes:UP000008205};
RN   [1] {ECO:0000313|EMBL:CAS07961.1, ECO:0000313|Proteomes:UP000008205}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=E2348/69 / EPEC {ECO:0000313|Proteomes:UP000008205};
RX   PubMed=18952797; DOI=10.1128/JB.01238-08;
RA   Iguchi A., Thomson N.R., Ogura Y., Saunders D., Ooka T.,
RA   Henderson I.R., Harris D., Asadulghani M., Kurokawa K., Dean P.,
RA   Kenny B., Quail M.A., Thurston S., Dougan G., Hayashi T., Parkhill J.,
RA   Frankel G.;
RT   "Complete genome sequence and comparative genome analysis of
RT   enteropathogenic Escherichia coli O127:H6 strain E2348/69.";
RL   J. Bacteriol. 191:347-354(2009).
CC   -!- SIMILARITY: Belongs to the monovalent cation:proton antiporter 2
CC       (CPA2) transporter (TC 2.A.37) family.
CC       {ECO:0000256|SAAS:SAAS00568668}.
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DR   EMBL; FM180568; CAS07961.1; -; Genomic_DNA.
DR   RefSeq; WP_000546558.1; NC_011601.1.
DR   EnsemblBacteria; CAS07961; CAS07961; E2348C_0413.
DR   KEGG; ecg:E2348C_0413; -.
DR   HOGENOM; HOG000179078; -.
DR   KO; K03455; -.
DR   OMA; TTFSHEG; -.
DR   BioCyc; ECOL574521:E2348C_RS02165-MONOMER; -.
DR   Proteomes; UP000008205; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015299; F:solute:proton antiporter activity; IEA:InterPro.
DR   GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR   Gene3D; 1.20.1530.20; -; 1.
DR   InterPro; IPR006153; Cation/H_exchanger.
DR   InterPro; IPR004771; K/H_exchanger.
DR   InterPro; IPR038770; Na+/solute_symporter_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003148; RCK_N.
DR   Pfam; PF00999; Na_H_Exchanger; 1.
DR   Pfam; PF02254; TrkA_N; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   TIGRFAMs; TIGR00932; 2a37; 1.
DR   PROSITE; PS51201; RCK_N; 1.
PE   3: Inferred from homology;
DR   PRODOM; B7UKF8.
DR   SWISS-2DPAGE; B7UKF8.
KW   Antiport {ECO:0000256|SAAS:SAAS00460756};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008205};
KW   Ion transport {ECO:0000256|SAAS:SAAS01092081};
KW   Membrane {ECO:0000256|SAAS:SAAS00460792, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00460753,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00460739,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS01092095}.
FT   TRANSMEM      6     26       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     33     51       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     57     76       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     88    112       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    118    136       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    148    168       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    180    206       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    227    260       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    280    299       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    306    328       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    334    361       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    368    387       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      419    541       RCK N-terminal. {ECO:0000259|PROSITE:
FT                                PS51201}.
SQ   SEQUENCE   558 AA;  59436 MW;  67E9E778F3C08F4B CRC64;
     MHHTTPLITT IVGGLVLAFI LGMLANKLRI SPLVGYLLAG VLAGPFTPGF VADTKLAPEL
     AELGVILLMF GVGLHFSLKD LMAVKSIAIP GAIAQIAVAT LLGMALSAVL GWSLMTGIVF
     GLCLSTASTV VLLRALEERQ LIDSQRGQIA IGWLIVEDLV MVLTLVLLPA VAGMMEQGDV
     GFATLAVDMG ITIGKVIAFI AIMMLVGRRL VPWIMARSAA TGSRELFTLS VLALALGIAF
     GAVELFDVSF ALGAFFAGMV LNESELSHRA AHDTLPLRDA FAVLFFVSVG MLFDPLILIQ
     QPLAVLATLA IILFGKSVAA LFLVRLFGHS QRTALTIAAS LAQIGEFAFI LAGLGMALNL
     LPQAGQNLVL AGAILSIMLN PVLFALLEKY LAKTETLEEQ TLEEAIEEEK QIPVDICNHA
     LLVGYGRVGS LLGEKLLASD IPLVVIETSR TRVDELRERG VRAVLGNAAN EEIMQLAHLE
     CAKWLILTIP NGYEAGEIVA SARAKNPDIE IIARAHYDDE VAYITERGAN QVVMGEREIA
     RTMLELLETP PAGEVVTG
//

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