(data stored in ACNUC7421 zone)

SWISSPROT: CRCB_ECO27

ID   CRCB_ECO27              Reviewed;         127 AA.
AC   B7UKR6;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   08-MAY-2019, entry version 54.
DE   RecName: Full=Putative fluoride ion transporter CrcB {ECO:0000255|HAMAP-Rule:MF_00454};
GN   Name=crcB {ECO:0000255|HAMAP-Rule:MF_00454};
GN   OrderedLocusNames=E2348C_0525;
OS   Escherichia coli O127:H6 (strain E2348/69 / EPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=574521;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=E2348/69 / EPEC;
RX   PubMed=18952797; DOI=10.1128/JB.01238-08;
RA   Iguchi A., Thomson N.R., Ogura Y., Saunders D., Ooka T.,
RA   Henderson I.R., Harris D., Asadulghani M., Kurokawa K., Dean P.,
RA   Kenny B., Quail M.A., Thurston S., Dougan G., Hayashi T., Parkhill J.,
RA   Frankel G.;
RT   "Complete genome sequence and comparative genome analysis of
RT   enteropathogenic Escherichia coli O127:H6 strain E2348/69.";
RL   J. Bacteriol. 191:347-354(2009).
CC   -!- FUNCTION: Important for reducing fluoride concentration in the
CC       cell, thus reducing its toxicity. {ECO:0000255|HAMAP-
CC       Rule:MF_00454}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_00454}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_00454}.
CC   -!- SIMILARITY: Belongs to the CrcB (TC 9.B.71) family.
CC       {ECO:0000255|HAMAP-Rule:MF_00454}.
DR   EMBL; FM180568; CAS08073.1; -; Genomic_DNA.
DR   RefSeq; WP_000939738.1; NC_011601.1.
DR   SMR; B7UKR6; -.
DR   EnsemblBacteria; CAS08073; CAS08073; E2348C_0525.
DR   KEGG; ecg:E2348C_0525; -.
DR   KO; K06199; -.
DR   OMA; FLMFESF; -.
DR   BioCyc; ECOL574521:E2348C_RS02760-MONOMER; -.
DR   Proteomes; UP000008205; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0015103; F:inorganic anion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00454; CrcB; 1.
DR   InterPro; IPR003691; CrcB.
DR   PANTHER; PTHR28259; PTHR28259; 1.
DR   Pfam; PF02537; CRCB; 1.
DR   TIGRFAMs; TIGR00494; crcB; 1.
PE   3: Inferred from homology;
DR   PRODOM; B7UKR6.
DR   SWISS-2DPAGE; B7UKR6.
KW   Cell inner membrane; Cell membrane; Complete proteome; Membrane;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN         1    127       Putative fluoride ion transporter CrcB.
FT                                /FTId=PRO_1000135320.
FT   TRANSMEM      4     24       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00454}.
FT   TRANSMEM     35     55       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00454}.
FT   TRANSMEM     71     91       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00454}.
FT   TRANSMEM    103    123       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00454}.
SQ   SEQUENCE   127 AA;  13765 MW;  492499959425EFE7 CRC64;
     MLQLLLAVFI GGGTGSVARW LLSMRFNPLH QAIPLGTLAA NLIGAFIIGM GFAWFSRMTN
     IDPVWKVLIT TGFCGGLTTF STFSAEVVFL LQEGRFGWAL LNVFVNLLGS FAMTALAFWL
     FSASTAH
//

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