(data stored in ACNUC7421 zone)

SWISSPROT: KDPA_ECO27

ID   KDPA_ECO27              Reviewed;         557 AA.
AC   B7UKX7;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   05-DEC-2018, entry version 58.
DE   RecName: Full=Potassium-transporting ATPase potassium-binding subunit {ECO:0000255|HAMAP-Rule:MF_00275};
DE   AltName: Full=ATP phosphohydrolase [potassium-transporting] A chain {ECO:0000255|HAMAP-Rule:MF_00275};
DE   AltName: Full=Potassium-binding and translocating subunit A {ECO:0000255|HAMAP-Rule:MF_00275};
DE   AltName: Full=Potassium-translocating ATPase A chain {ECO:0000255|HAMAP-Rule:MF_00275};
GN   Name=kdpA {ECO:0000255|HAMAP-Rule:MF_00275};
GN   OrderedLocusNames=E2348C_0587;
OS   Escherichia coli O127:H6 (strain E2348/69 / EPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=574521;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=E2348/69 / EPEC;
RX   PubMed=18952797; DOI=10.1128/JB.01238-08;
RA   Iguchi A., Thomson N.R., Ogura Y., Saunders D., Ooka T.,
RA   Henderson I.R., Harris D., Asadulghani M., Kurokawa K., Dean P.,
RA   Kenny B., Quail M.A., Thurston S., Dougan G., Hayashi T., Parkhill J.,
RA   Frankel G.;
RT   "Complete genome sequence and comparative genome analysis of
RT   enteropathogenic Escherichia coli O127:H6 strain E2348/69.";
RL   J. Bacteriol. 191:347-354(2009).
CC   -!- FUNCTION: Part of the high-affinity ATP-driven potassium transport
CC       (or Kdp) system, which catalyzes the hydrolysis of ATP coupled
CC       with the electrogenic transport of potassium into the cytoplasm.
CC       This subunit binds and transports the potassium across the
CC       cytoplasmic membrane. {ECO:0000255|HAMAP-Rule:MF_00275}.
CC   -!- SUBUNIT: The system is composed of three essential subunits: KdpA,
CC       KdpB and KdpC. {ECO:0000255|HAMAP-Rule:MF_00275}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_00275}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_00275}.
CC   -!- SIMILARITY: Belongs to the KdpA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00275}.
DR   EMBL; FM180568; CAS08135.1; -; Genomic_DNA.
DR   RefSeq; WP_000741161.1; NC_011601.1.
DR   SMR; B7UKX7; -.
DR   PRIDE; B7UKX7; -.
DR   EnsemblBacteria; CAS08135; CAS08135; E2348C_0587.
DR   KEGG; ecg:E2348C_0587; -.
DR   KO; K01546; -.
DR   OMA; WQNYGGE; -.
DR   BioCyc; ECOL574521:E2348C_RS03115-MONOMER; -.
DR   Proteomes; UP000008205; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0030955; F:potassium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0008556; F:potassium-transporting ATPase activity; IEA:InterPro.
DR   HAMAP; MF_00275; KdpA; 1.
DR   InterPro; IPR004623; KdpA.
DR   PANTHER; PTHR30607; PTHR30607; 1.
DR   Pfam; PF03814; KdpA; 1.
DR   PIRSF; PIRSF001294; K_ATPaseA; 1.
DR   TIGRFAMs; TIGR00680; kdpA; 1.
PE   3: Inferred from homology;
DR   PRODOM; B7UKX7.
DR   SWISS-2DPAGE; B7UKX7.
KW   Cell inner membrane; Cell membrane; Complete proteome; Ion transport;
KW   Membrane; Potassium; Potassium transport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN         1    557       Potassium-transporting ATPase potassium-
FT                                binding subunit.
FT                                /FTId=PRO_1000190736.
FT   TRANSMEM      5     25       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00275}.
FT   TRANSMEM     63     83       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00275}.
FT   TRANSMEM    132    152       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00275}.
FT   TRANSMEM    170    190       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00275}.
FT   TRANSMEM    253    273       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00275}.
FT   TRANSMEM    283    303       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00275}.
FT   TRANSMEM    329    349       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00275}.
FT   TRANSMEM    356    376       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00275}.
FT   TRANSMEM    379    399       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00275}.
FT   TRANSMEM    416    436       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00275}.
FT   TRANSMEM    484    504       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00275}.
FT   TRANSMEM    526    546       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00275}.
SQ   SEQUENCE   557 AA;  59076 MW;  ED3A136CA56BE3CA CRC64;
     MAAQGFLLIA TFLLVLMVLA RPLGSGLARL INDIPLPGTT GVERVLFSTL GVSDREMNWK
     QYLSAILGLN ILGLAVLFFM LLGQHYLPLN PQQLPGLSWD LALNTAVSFV TNTNWQSYSG
     ETTLSYFSQM AGLTVQNFLS AASGIAVIFA LIRAFTRQSM NTLGNAWVDL LRITLWVLTP
     VALLIALFFI QQGVLQNFLP YQAVTTIEGA QQLLPMGPVA SQEAIKMLGT NGGGFFNANS
     SHPFENPTAL TNFVQMLAIF LIPTALCFAF GEVAGDRRQG RMLLWAMSVI FVICVGVVMW
     AEVQGNPHLL ALGADSSINM EGKESRFGVL VSSLFAVVTT AASCGAVIAM HDSFTALGGM
     VPMWLMQIGE VVFGGVGSGL YGMMLFVLLA VFIAGLMIGR TPEYLGKKID VREMKLTALA
     ILVTPTLVLM GAALAMMTDA GRSAMLNPGP HGFSEVLYAV SSAANNNGSA FAGLSANSPF
     WNCLLALCMF VGRFGVIIPV MAIAGSLVSK KSQPASSGTL PTHGPLFVGL LIGTVLLVGA
     LTFIPALALG PVAEYLS
//

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