(data stored in ACNUC7421 zone)

SWISSPROT: B7UKY2_ECO27

ID   B7UKY2_ECO27            Unreviewed;       493 AA.
AC   B7UKY2;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   05-DEC-2018, entry version 61.
DE   RecName: Full=Dipeptide permease D {ECO:0000256|HAMAP-Rule:MF_01880};
GN   Name=ybgH {ECO:0000313|EMBL:CAS08140.1};
GN   Synonyms=dtpD {ECO:0000256|HAMAP-Rule:MF_01880};
GN   OrderedLocusNames=E2348C_0592 {ECO:0000313|EMBL:CAS08140.1};
OS   Escherichia coli O127:H6 (strain E2348/69 / EPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=574521 {ECO:0000313|EMBL:CAS08140.1, ECO:0000313|Proteomes:UP000008205};
RN   [1] {ECO:0000313|EMBL:CAS08140.1, ECO:0000313|Proteomes:UP000008205}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=E2348/69 / EPEC {ECO:0000313|Proteomes:UP000008205};
RX   PubMed=18952797; DOI=10.1128/JB.01238-08;
RA   Iguchi A., Thomson N.R., Ogura Y., Saunders D., Ooka T.,
RA   Henderson I.R., Harris D., Asadulghani M., Kurokawa K., Dean P.,
RA   Kenny B., Quail M.A., Thurston S., Dougan G., Hayashi T., Parkhill J.,
RA   Frankel G.;
RT   "Complete genome sequence and comparative genome analysis of
RT   enteropathogenic Escherichia coli O127:H6 strain E2348/69.";
RL   J. Bacteriol. 191:347-354(2009).
CC   -!- FUNCTION: Probable proton-dependent permease that transports
CC       dipeptides. {ECO:0000256|HAMAP-Rule:MF_01880}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC       Rule:MF_01880}; Multi-pass membrane protein {ECO:0000256|HAMAP-
CC       Rule:MF_01880}.
CC   -!- SIMILARITY: Belongs to the PTR2/POT transporter (TC 2.A.17)
CC       family. DtpD subfamily. {ECO:0000256|HAMAP-Rule:MF_01880}.
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DR   EMBL; FM180568; CAS08140.1; -; Genomic_DNA.
DR   RefSeq; WP_001032720.1; NC_011601.1.
DR   EnsemblBacteria; CAS08140; CAS08140; E2348C_0592.
DR   KEGG; ecg:E2348C_0592; -.
DR   HOGENOM; HOG000243450; -.
DR   KO; K03305; -.
DR   OMA; MWERFCF; -.
DR   BioCyc; ECOL574521:E2348C_RS03140-MONOMER; -.
DR   Proteomes; UP000008205; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0071916; F:dipeptide transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015333; F:peptide:proton symporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   CDD; cd06174; MFS; 1.
DR   HAMAP; MF_01880; PTR2_DtpD_subfam; 1.
DR   InterPro; IPR023777; AA/pep_transptr_DtpD.
DR   InterPro; IPR005279; Dipep/tripep_permease.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR000109; POT_fam.
DR   InterPro; IPR018456; PTR2_symporter_CS.
DR   PANTHER; PTHR11654; PTHR11654; 1.
DR   Pfam; PF00854; PTR2; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR00924; yjdL_sub1_fam; 1.
DR   PROSITE; PS50850; MFS; 1.
DR   PROSITE; PS01022; PTR2_1; 1.
DR   PROSITE; PS01023; PTR2_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; B7UKY2.
DR   SWISS-2DPAGE; B7UKY2.
KW   Cell inner membrane {ECO:0000256|HAMAP-Rule:MF_01880};
KW   Cell membrane {ECO:0000256|HAMAP-Rule:MF_01880};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008205};
KW   Membrane {ECO:0000256|HAMAP-Rule:MF_01880};
KW   Peptide transport {ECO:0000256|HAMAP-Rule:MF_01880};
KW   Protein transport {ECO:0000256|HAMAP-Rule:MF_01880};
KW   Transmembrane {ECO:0000256|HAMAP-Rule:MF_01880};
KW   Transmembrane helix {ECO:0000256|HAMAP-Rule:MF_01880};
KW   Transport {ECO:0000256|HAMAP-Rule:MF_01880}.
FT   TRANSMEM     12     36       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01880}.
FT   TRANSMEM     48     69       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01880}.
FT   TRANSMEM     78     96       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01880}.
FT   TRANSMEM    102    121       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01880}.
FT   TRANSMEM    142    162       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01880}.
FT   TRANSMEM    168    187       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01880}.
FT   TRANSMEM    208    231       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01880}.
FT   TRANSMEM    237    255       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01880}.
FT   TRANSMEM    267    284       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01880}.
FT   TRANSMEM    304    332       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01880}.
FT   TRANSMEM    344    365       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01880}.
FT   TRANSMEM    377    398       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01880}.
FT   TRANSMEM    410    430       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01880}.
FT   TRANSMEM    462    479       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_01880}.
FT   DOMAIN       10    483       MFS. {ECO:0000259|PROSITE:PS50850}.
SQ   SEQUENCE   493 AA;  54097 MW;  7C6EAE958A400862 CRC64;
     MNKHASQPRA IYYVVALQIW EYFSFYGMRA LLILYLTNQL KYSDNHAYEL FSAYCSLVYV
     TPILGGFLAD KVLGNRMAVM LGALLMAIGH VVLGASEIHP SFLYLSLAII VCGYGLFKSN
     VSCLLGELYE PTDPRRDGGF SLMYAAGNVG SIIAPIACGF AQEEYSWAMG FGLAAVGMIA
     GLVIFLCGNR HFTHTRGVNK KVLRATNFLL PNWGWLLVLL VATPALITVL FWKEWSVYAL
     IVATIIGLGV LAKIYRKAEN QKQRKELGLI VTLTFFSMLF WAFAQQGGSS ISLYIDRFVN
     RDIFGYTVPT AMFQSINAFA VMLCGVFLAW VVKESVAGNR TVRIWGKFAL GLGLMSAGFC
     ILTLSARWSA MYGHSSLPLM VLGLAVMGFA ELFIDPVAMS QITRIEIPGV TGVLTGIYML
     LSGAIANYLA GVIADQTSQA SFDASGAINY SINAYIEVFD QITWGALACV GLVLMIWLYQ
     ALKFRNRALA LES
//

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