(data stored in ACNUC9543 zone)

SWISSPROT: C0H4Q9_PLAF7

ID   C0H4Q9_PLAF7            Unreviewed;      1419 AA.
AC   C0H4Q9;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   11-DEC-2019, entry version 51.
DE   SubName: Full=Inositol 5-phosphatase, putative {ECO:0000313|EMBL:CAX64086.1};
DE            EC=3.1.3.36 {ECO:0000313|EMBL:CAX64086.1};
GN   ORFNames=PF3D7_0802500 {ECO:0000313|EMBL:CAX64086.1};
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329 {ECO:0000313|EMBL:CAX64086.1, ECO:0000313|Proteomes:UP000001450};
RN   [1] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D.,
RA   Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S.,
RA   Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA   Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A.,
RA   Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA   Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA   Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G.;
RT   "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL   Nature 419:498-511(2002).
RN   [2] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368867; DOI=10.1038/nature01095;
RA   Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA   Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA   Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T.,
RA   Christodoulou Z., Clark L., Clark R., Corton C., Cronin A., Davies R.M.,
RA   Davis P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A.,
RA   Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H.,
RA   Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James K.D.,
RA   Johnson D., Kerhornou A., Knights A., Konfortov B., Kyes S., Larke N.,
RA   Lawson D., Lennard N., Line A., Maddison M., Mclean J., Mooney P.,
RA   Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A.,
RA   Rabbinowitsch E., Rajandream M.A., Rutter S., Rutherford K.M., Sanders M.,
RA   Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S.,
RA   Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA   Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT   "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL   Nature 419:527-531(2002).
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DR   EMBL; AL844507; CAX64086.1; -; Genomic_DNA.
DR   RefSeq; XP_002808809.1; XM_002808763.1.
DR   EnsemblProtists; CAX64086; CAX64086; PF3D7_0802500.
DR   GeneDB; PF3D7_0802500.1:pep; -.
DR   GeneID; 2655398; -.
DR   KEGG; pfa:PF3D7_0802500; -.
DR   EuPathDB; PlasmoDB:PF3D7_0802500; -.
DR   HOGENOM; HOG000284487; -.
DR   InParanoid; C0H4Q9; -.
DR   OMA; DNNNRCD; -.
DR   Proteomes; UP000001450; Chromosome 8.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR   InterPro; IPR002013; SAC_dom.
DR   Pfam; PF02383; Syja_N; 1.
DR   PROSITE; PS50275; SAC; 1.
PE   4: Predicted;
DR   PRODOM; C0H4Q9.
DR   SWISS-2DPAGE; C0H4Q9.
KW   Hydrolase {ECO:0000313|EMBL:CAX64086.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001450};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        802..819
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        840..862
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          136..472
FT                   /note="SAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50275"
SQ   SEQUENCE   1419 AA;  173061 MW;  83388ED3DAA5A4C6 CRC64;
     MYARSLTCFR VYKIYSNKDG IFVIGINKKE NVYQVTELKR RSKEIEIVDH FKLYMKRDYC
     NYIIRKRLEY ICKCEGIFGC IRFLNYPYLY VLIKKEKVGI LFDEHKIYNV KNILLIPFVE
     DIFDNYNEEN ELIDLFYNNT NHKYIYFSYT YNLTYSVQEN YFIQKNYLKG GNVKYKNNPY
     MWNSYHSKYF IKQNIFLCLS IINGYFIQSK FLCSGKIIDI SLVGRRSNKY AGTRFRKRGL
     NSYGYSANDV ESEIILFEKN NSHVILSYTQ LRGSVPIFWN QQVNYKILKK PQINFLKTDI
     NYSCTQKHFQ RLYEKYGYPI TVVNLLSKKK YSDEQKLSYH YKESIDRLNK YIPKKIHIIY
     KHVDLRKAYK IGIKYTQYIL KMLYNFSLHT IGFFYMNNKK VILIQTGVLR FNCVDCLDRT
     NAAQLFLNIY MFMKFIKLIK LIKKNDLSVQ NISHISKLYE ELGDAISKQY AGSTAHKKYT
     PGQHSNFFIQ SKELFTSLKR YYISSFNDLE KQKSINLFLG VTHNKLHCIN NSHDLDTFAH
     NKYFKDNGKN IFWWVLPLDK FYYKAQTLLN LKHHDIIIKQ KKKRKKRYIE LKMKKMKKIK
     KLKKLKKFKT MKKFKTMKKF MYTYNNSTTT NRKISASKYK QREKKILSDV HMLEELYRNY
     RRGEESKRML KIRRTKNILR NRKDVKSKHI NKKQDFISKM YDNLKFYKCF SNTNIFKHMY
     NFNNAEQLFL EKTGISLKNN LFFERMNYLF NMRRVGNSNE RCDNNNRCDN NNRCDNNNRC
     DGDKSKYGVV LHNNIEMNPR SFILFFKYMS HICNFYNVYK NNFHYFFKNR NIFRYRIWRL
     ISCYNYLNYL KIYFNIFFLL YYSICNKYNI KLIYMNHVKE LIYFTKSYNC KDLQKKSDQN
     KKTKKYFTNY NNHINNHVII NPSSFEKDVK HIVSNFQRYK NIPMLIDYYI NYFQINYIPY
     NYMLINISSV LCDVNMKDNM KKKLTKDGIK KKIINNNNMN QREHSFYHGK THTCSISPLD
     YDDDDDNMLN RCSSISEAYN IVTKDDQRIN INMLNEEKNG NSHMCGNYVK KKNTSDNSFD
     NNSNLIIYRN EKKKKIKGSS IYYKCYIYKR YEKEKKDEKY KRDKNYNISQ LPYIYSPFYF
     NTKIIKFLLF VYSTYCCNEI NKYNNIYNKN DKLYTYPADF YNHCNNSYNQ IKKMIDMDNE
     LIKRDGNNMQ SSNKLYYYNI VFFLKKLFVT KSVDLYFIEL YLSYIYKTNY YKEFDVYFYQ
     NIKYPFYNNM KNKKSEEKLF LNNYDSFENI HKKKKEVSRI HKKIYNEVKN NYNNLSRKYV
     YIKKFETHYS QEMNSYKKRD QQIKRFFKNK ITSFNNQMKN YNILFNNFKH YIKENEKYKQ
     NSNYVHDHLD NFNVLKDKIE NSMNYHQYCH PVGRKIFTT
//

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