(data stored in ACNUC9543 zone)

SWISSPROT: C0H4S0_PLAF7

ID   C0H4S0_PLAF7            Unreviewed;      1212 AA.
AC   C0H4S0;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   11-DEC-2019, entry version 62.
DE   SubName: Full=AAA family ATPase, putative {ECO:0000313|EMBL:CAX64096.1};
GN   ORFNames=PF3D7_0806000 {ECO:0000313|EMBL:CAX64096.1};
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329 {ECO:0000313|EMBL:CAX64096.1, ECO:0000313|Proteomes:UP000001450};
RN   [1] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D.,
RA   Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S.,
RA   Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA   Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A.,
RA   Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA   Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA   Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G.;
RT   "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL   Nature 419:498-511(2002).
RN   [2] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368867; DOI=10.1038/nature01095;
RA   Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA   Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA   Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T.,
RA   Christodoulou Z., Clark L., Clark R., Corton C., Cronin A., Davies R.M.,
RA   Davis P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A.,
RA   Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H.,
RA   Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James K.D.,
RA   Johnson D., Kerhornou A., Knights A., Konfortov B., Kyes S., Larke N.,
RA   Lawson D., Lennard N., Line A., Maddison M., Mclean J., Mooney P.,
RA   Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A.,
RA   Rabbinowitsch E., Rajandream M.A., Rutter S., Rutherford K.M., Sanders M.,
RA   Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S.,
RA   Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA   Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT   "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL   Nature 419:527-531(2002).
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DR   EMBL; AL844507; CAX64096.1; -; Genomic_DNA.
DR   RefSeq; XP_002808819.1; XM_002808773.1.
DR   SMR; C0H4S0; -.
DR   PRIDE; C0H4S0; -.
DR   EnsemblProtists; CAX64096; CAX64096; PF3D7_0806000.
DR   GeneDB; PF3D7_0806000.1:pep; -.
DR   GeneID; 2655316; -.
DR   KEGG; pfa:PF3D7_0806000; -.
DR   EuPathDB; PlasmoDB:PF3D7_0806000; -.
DR   HOGENOM; HOG000212562; -.
DR   InParanoid; C0H4S0; -.
DR   OMA; MNLNAHM; -.
DR   Proteomes; UP000001450; Chromosome 8.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATPase activity; IBA:GO_Central.
DR   GO; GO:1990275; F:preribosome binding; IBA:GO_Central.
DR   GO; GO:0051973; P:positive regulation of telomerase activity; IBA:GO_Central.
DR   GO; GO:0042254; P:ribosome biogenesis; IBA:GO_Central.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00004; AAA; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   4: Predicted;
DR   PRODOM; C0H4S0.
DR   SWISS-2DPAGE; C0H4S0.
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001450}.
FT   DOMAIN          979..1123
FT                   /note="AAA"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   COILED          28..48
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          452..476
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1212 AA;  145702 MW;  AEAA69FFC03E8293 CRC64;
     MSTKENDKVI ENFCVYDHSN KCFSYLKIKK REIKKEKYQN EYERLVNRKC MYNYEWIKNL
     SYEKCIDYIT KNSFKNLKEE KYVNKYARKC KKNISSLCST KQNEECCFLN NTKFLKEAKN
     IKNALHCINR NKGKYKPQLF VDNIFKMKKR YENIEYKHEH MIREHKLNDH DGYEKGLVEL
     SNKKKMVITD GDNNVNNVNN VNNVNNVNNV NNVNNVNNVN NVNNVNNVNN VNNVNNVNNV
     NNVNNVNNVN NVNNVNNVNN VNNVNNVNMF KMKNNFDESY NHPFDISFRK KYYEKISRLW
     LKNFVKKNGK VHKNLAKKLI KCVIIKNFII FDVELWNIFL KKNITNHFNT NLYFLTGKIG
     NMKSVFLNNI FCSFPFLYKN DHMFMIDISN YEDHTIVCDY RYLMDPMYVN TNEEYNIKKK
     LKKKKKKLSS FKMWDTFDDI KNKEKYSKLI NLKVYNDKLK NKVRLCEEEE KNNNNNNNNN
     KNYYHVQNKN YKNVDIINMK YDNIMFFEEK FQSDSSYELI NFKTNQFQKK KINISDDQKY
     NNNYEKKLYV QKVLYPYYYE LVLKEKLITD INMITSYDPL NFNLEYILIH FTRQAIIKQF
     VWKRKMYKWL KGIFNKSQGK QGMKKVNVNV GRKNDDDYEN VYINKKMNMN LGLDLFNGGI
     SFLLIKNLEY INNFPIHKKN CIIFLLLKYI YMWKNMNLNA HMFIISSSSS TSHNNNNNNK
     NNNVINNIKI YNNSSDNISS LFNIYMNNYF VFVFPNFLHS SNRYKLLINL FKKYKLYYCK
     NEIKELAKIT NNFNIDNIKK LFQDEYRERI IDHLEKRKED TSQEIITKNS CIIKDIFQKA
     RKGKNQFFSK SLNLQQDSHI YIHMHEIEMY KKKKYEMFSK SGIFENYGFN EVIGEDELIT
     QLKNQIVSKF NMKESKNMGL NKIDMYDMVN DNVNVNNNNN NIKEDGINNI HENYKSHYNK
     EMHVSNSMWE NISNFNELDT VGILLHGNSG SGKSFIAKKI VEECNCNSVI INCSNIFNKV
     MGESEKFLNE IFEYCINKLQ PCILLLDNIE TICYKEDYIT VENFTTRLKL CFYENIDKIH
     YEKKWKRNPC LLLIIATTNN INNIDDNLLT HYRFKYIYQT THFQYWKEQD IYKLFYKYLK
     NNNIESTHFL YSHKFKHFVD EHIIKVQYKL SPLYIYNLCT YALAYRLRNA LKGNENELDV
     EDFYEAIKRM IY
//

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