(data stored in ACNUC9543 zone)

SWISSPROT: C0H4T9_PLAF7

ID   C0H4T9_PLAF7            Unreviewed;      1774 AA.
AC   C0H4T9;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   08-MAY-2019, entry version 55.
DE   SubName: Full=CCR4-associated factor 1 {ECO:0000313|EMBL:CAX64115.1};
GN   ORFNames=PF3D7_0811300 {ECO:0000313|EMBL:CAX64115.1};
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329 {ECO:0000313|EMBL:CAX64115.1, ECO:0000313|Proteomes:UP000001450};
RN   [1] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.,
RA   Eisen J.A., Rutherford K., Salzberg S.L., Craig A., Kyes S.,
RA   Chan M.S., Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S.,
RA   Pertea M., Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B.,
RA   Martin D.M., Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A.,
RA   McFadden G.I., Cummings L.M., Subramanian G.M., Mungall C.,
RA   Venter J.C., Carucci D.J., Hoffman S.L., Newbold C., Davis R.W.,
RA   Fraser C.M., Barrell B.;
RT   "Genome sequence of the human malaria parasite Plasmodium
RT   falciparum.";
RL   Nature 419:498-511(2002).
RN   [2] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368867; DOI=10.1038/nature01095;
RA   Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA   Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA   Buckee C.O., Burrows C., Cherevach I., Chillingworth C.,
RA   Chillingworth T., Christodoulou Z., Clark L., Clark R., Corton C.,
RA   Cronin A., Davies R.M., Davis P., Dear P., Dearden F., Doggett J.,
RA   Feltwell T., Goble A., Goodhead I., Gwilliam R., Hamlin N., Hance Z.,
RA   Harper D., Hauser H., Hornsby T., Holroyd S., Horrocks P.,
RA   Humphray S., Jagels K., James K.D., Johnson D., Kerhornou A.,
RA   Knights A., Konfortov B., Kyes S., Larke N., Lawson D., Lennard N.,
RA   Line A., Maddison M., Mclean J., Mooney P., Moule S., Murphy L.,
RA   Oliver K., Ormond D., Price C., Quail M.A., Rabbinowitsch E.,
RA   Rajandream M.A., Rutter S., Rutherford K.M., Sanders M., Simmonds M.,
RA   Seeger K., Sharp S., Smith R., Squares R., Squares S., Stevens K.,
RA   Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA   Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT   "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL   Nature 419:527-531(2002).
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DR   EMBL; AL844507; CAX64115.1; -; Genomic_DNA.
DR   RefSeq; XP_002808838.1; XM_002808792.1.
DR   SMR; C0H4T9; -.
DR   PRIDE; C0H4T9; -.
DR   EnsemblProtists; CAX64115; CAX64115; PF3D7_0811300.
DR   GeneDB; PF3D7_0811300.1:pep; -.
DR   GeneID; 2655222; -.
DR   KEGG; pfa:PF3D7_0811300; -.
DR   EuPathDB; PlasmoDB:PF3D7_0811300; -.
DR   InParanoid; C0H4T9; -.
DR   KO; K12581; -.
DR   OMA; TATINYK; -.
DR   BioCyc; PLASMO:MAL8P1.104-MONOMER; -.
DR   Proteomes; UP000001450; Chromosome 8.
DR   GO; GO:0030015; C:CCR4-NOT core complex; IBA:GO_Central.
DR   GO; GO:0000932; C:P-body; IBA:GO_Central.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0004535; F:poly(A)-specific ribonuclease activity; IBA:GO_Central.
DR   GO; GO:0043928; P:exonucleolytic catabolism of deadenylated mRNA; IBA:GO_Central.
DR   GO; GO:0017148; P:negative regulation of translation; IBA:GO_Central.
DR   Gene3D; 3.30.420.10; -; 1.
DR   InterPro; IPR039637; CNOT7/CNOT8/Pop2.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   PANTHER; PTHR10797; PTHR10797; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
PE   4: Predicted;
DR   PRODOM; C0H4T9.
DR   SWISS-2DPAGE; C0H4T9.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001450};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001450}.
SQ   SEQUENCE   1774 AA;  200212 MW;  592115F3C2F4A8A3 CRC64;
     MDERTKIVDV WANNLEEEFE RIRDIVEKHP YVAIDTEFPG IVARPTGNVL DYNYQTIKCN
     VDLLKVIQLG VTFSNGKGEM PNVSTWQFNF KFDLDSDMYA QNSIDFLKLS GINFEKHQSL
     GIELLHFGEV IMSSGLVMNE DVKWISFHGC YDFAYLLKIL TCSALPHNEA AFFELLNDFF
     PSLYDIKYLL LNLNIKQLSR TFSLQKISEI LSVKRIGRQH QAGSDSLVTC KTFFKLMEMY
     FDNKIDDKKY SGIIYGLGST IKNYNPKLDD HNNNRYHNHH NNYNNHNYVK NSNNNNNNNK
     YNNNSNNSNN SNNNNNNNNN NNNNNNNSSN NNNNSNNNNN NNSINSHHSH NNNNMLMNAP
     NNNPMSNYID AKEYHPTGFN KEIPKLHNKN DVMFHMYADN NQNSYNNISS NINNIHGTNN
     YITNAIYSSD TVNNYVLNKF VNNSPPSPSS SLSSPPHPPH LPHPPQLLNN TVNKNVRLSL
     NTSSYMNSKS TDPIGINNHN NNNNLSSSSR SYMASYPSSG IKNSLDTSKI MGPIYNDIPR
     NITGNLNSDL NNIANENMMN INGLTNGNNL SPTLSANNGI MSPSLSNANN GLLNLNNTNL
     NNSINNTING SLILGGMNNN GHTNNNINNN HNNNGNAINM NMNGMGIMNS SMNISGLSTN
     LNMNNLYGDI RSLGGSTSNI NLNNINSMNE LNNLKSGSIS NISNCDENMI GLNKNIYSTN
     NGPLIGNMIN NNVYNANINY NNYNYNSINT NNSSNNSFLN SVNYNTAYAH GNNPSISPGG
     NNNMSTNNYY SIQNKYSNFG KYSSNLNYVN PLSQSINEVK SMAGEDYCDI DKRSIDNLGS
     SKNSFANNKN LLGKINNNNN NNIISSSSST SHHINFKNTI SNNNSNINNN NLNINSTTSV
     HPMNNPNMND TNNLNIKRNM KNESFISDLS TNKNELNNMG DHVGMENLNM LVQNMNIKRD
     EKYKDEKINN NNNMSKNMML NLNNNSSISN VNNLNNMMNS NNDLIKNNNT TYMKNINMSI
     SNINNGVTNT VLNTDLKVSS NLNQNGINVT NSTTYISANS LDNNNNNNNL NSGNNINDHG
     NNSGKGINHT NPTIINNDNK INVASHNKGN TSIDGNWING PINNTNSSNK YSEGKDKDAN
     TEDNKIGYKA NDNNNNSSNN NRNNNGKVLS NNKNSNKGNN KNSKNKSKNN NDPNKKASGD
     NLNEPDYKEN NMNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNSNNNNSNN NNSNNNNNSN
     NNNNNNNNNN NSNNNNNNSN NNNNNNNNNN NNNNNSNNNN YNNSNNNNNN HSTLISNNDN
     TIVSNNDNED NSNHTTNNNE QDKDDKNNNM KTEGNHSKFS KQHGNMNTRN KNNDKNNFVN
     NSNLVNSNVE DVNNFNNIIN QRNHCNKNYI NFIKEDQQEV DQKELHASNI SHMLNEDNSN
     EIMDKNTSYN NPYNNNANYY KSDNIKLYRG FEKNSSHQLI LKNNFSNNSN MTENEGIIMH
     DMNKMNNPNN ADILLGNENL LGIKNLNNYM NPNVHNTERN NELNNNNTNM ITNKKNVNSC
     NNDMLHKQIN NFNIININKV HNNISNSLFS NNMSNYNVVS ENVNINNNSN TNNTANNNFM
     NKKNSKANLN VFNQSLINNL NLNLNNFYLN NENSFNKINM NYSNINSTSY YFNTNDNNMN
     NTQHYYSSFI PEHFATDKIV TKQSSENNNN INNSSTMYKE KKEEPNLNFK EKNFVDKNLP
     TEKYPGAVLE TVDNNFGYPN YEYKTKDHKY FYDN
//

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