(data stored in ACNUC9543 zone)

SWISSPROT: C0H4U4_PLAF7

ID   C0H4U4_PLAF7            Unreviewed;       315 AA.
AC   C0H4U4;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   11-DEC-2019, entry version 51.
DE   RecName: Full=NPL domain-containing protein {ECO:0000259|Pfam:PF17800};
GN   ORFNames=PF3D7_0813300 {ECO:0000313|EMBL:CAX64120.1};
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329 {ECO:0000313|EMBL:CAX64120.1, ECO:0000313|Proteomes:UP000001450};
RN   [1] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D.,
RA   Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S.,
RA   Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA   Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A.,
RA   Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA   Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA   Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G.;
RT   "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL   Nature 419:498-511(2002).
RN   [2] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368867; DOI=10.1038/nature01095;
RA   Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA   Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA   Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T.,
RA   Christodoulou Z., Clark L., Clark R., Corton C., Cronin A., Davies R.M.,
RA   Davis P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A.,
RA   Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H.,
RA   Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James K.D.,
RA   Johnson D., Kerhornou A., Knights A., Konfortov B., Kyes S., Larke N.,
RA   Lawson D., Lennard N., Line A., Maddison M., Mclean J., Mooney P.,
RA   Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A.,
RA   Rabbinowitsch E., Rajandream M.A., Rutter S., Rutherford K.M., Sanders M.,
RA   Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S.,
RA   Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA   Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT   "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL   Nature 419:527-531(2002).
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DR   EMBL; AL844507; CAX64120.1; -; Genomic_DNA.
DR   RefSeq; XP_002808843.1; XM_002808797.1.
DR   PRIDE; C0H4U4; -.
DR   EnsemblProtists; CAX64120; CAX64120; PF3D7_0813300.
DR   GeneDB; PF3D7_0813300.1:pep; -.
DR   GeneID; 2655446; -.
DR   KEGG; pfa:PF3D7_0813300; -.
DR   EuPathDB; PlasmoDB:PF3D7_0813300; -.
DR   HOGENOM; HOG000280946; -.
DR   InParanoid; C0H4U4; -.
DR   KO; K11276; -.
DR   OMA; ANGCYNI; -.
DR   Proteomes; UP000001450; Chromosome 8.
DR   InterPro; IPR041232; NPL.
DR   Pfam; PF17800; NPL; 1.
PE   4: Predicted;
DR   PRODOM; C0H4U4.
DR   SWISS-2DPAGE; C0H4U4.
KW   Reference proteome {ECO:0000313|Proteomes:UP000001450}.
FT   DOMAIN          2..94
FT                   /note="NPL"
FT                   /evidence="ECO:0000259|Pfam:PF17800"
FT   REGION          135..260
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        150..223
FT                   /note="Acidic"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        224..260
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   315 AA;  36256 MW;  F02072A3D901EBC3 CRC64;
     MFYGKVVKPD ETVVPEVKDG YSVIHLSRAC LNNPEHEGKI YVQVEDGNGC YNICCLQKNV
     CEDTPLDIFL MLDNDVKIKT SGSSNEVHIV GYYEVSFGQD NLDEDEDEFE DEFDNDEVRM
     LTKKNTLKNS LSNGISKRKK NLENNEDDET NVGRNDEDDD DEDDEDDEDE EEDDDEEDED
     DEEDDEDDDD EEEEDEEDED EEGEDEDDEE DEEEEEEEDE EGEDVENKKK GGDKKKNKRS
     LDNKSDGPLK KSKIDDEGQF EKDLVAFLKK NGKSKLTELG KVKKPEGLKM KLGFFIKKHS
     NVFKFDTEGQ IVSLK
//

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