(data stored in SCRATCH zone)

SWISSPROT: C0H4V2_PLAF7

ID   C0H4V2_PLAF7            Unreviewed;       830 AA.
AC   C0H4V2;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   11-DEC-2019, entry version 72.
DE   SubName: Full=tRNA modification GTPase, putative {ECO:0000313|EMBL:CAX64129.1};
DE            EC=3.6.5.1 {ECO:0000313|EMBL:CAX64129.1};
GN   ORFNames=PF3D7_0817100 {ECO:0000313|EMBL:CAX64129.1};
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329 {ECO:0000313|EMBL:CAX64129.1, ECO:0000313|Proteomes:UP000001450};
RN   [1] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D.,
RA   Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S.,
RA   Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA   Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A.,
RA   Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA   Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA   Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G.;
RT   "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL   Nature 419:498-511(2002).
RN   [2] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368867; DOI=10.1038/nature01095;
RA   Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA   Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA   Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T.,
RA   Christodoulou Z., Clark L., Clark R., Corton C., Cronin A., Davies R.M.,
RA   Davis P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A.,
RA   Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H.,
RA   Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James K.D.,
RA   Johnson D., Kerhornou A., Knights A., Konfortov B., Kyes S., Larke N.,
RA   Lawson D., Lennard N., Line A., Maddison M., Mclean J., Mooney P.,
RA   Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A.,
RA   Rabbinowitsch E., Rajandream M.A., Rutter S., Rutherford K.M., Sanders M.,
RA   Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S.,
RA   Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA   Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT   "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL   Nature 419:527-531(2002).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL844507; CAX64129.1; -; Genomic_DNA.
DR   RefSeq; XP_002808852.1; XM_002808806.1.
DR   EnsemblProtists; CAX64129; CAX64129; PF3D7_0817100.
DR   GeneDB; PF3D7_0817100.1:pep; -.
DR   GeneID; 9221950; -.
DR   KEGG; pfa:PF3D7_0817100; -.
DR   EuPathDB; PlasmoDB:PF3D7_0817100; -.
DR   InParanoid; C0H4V2; -.
DR   KO; K03650; -.
DR   OMA; CVNKCDL; -.
DR   PhylomeDB; C0H4V2; -.
DR   Proteomes; UP000001450; Chromosome 8.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   Gene3D; 1.20.120.430; -; 1.
DR   Gene3D; 3.30.1360.120; -; 2.
DR   InterPro; IPR018948; GTP-bd_TrmE_N.
DR   InterPro; IPR006073; GTP_binding_domain.
DR   InterPro; IPR027368; MnmE_dom2.
DR   InterPro; IPR025867; MnmE_helical.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   Pfam; PF01926; MMR_HSR1; 1.
DR   Pfam; PF12631; MnmE_helical; 1.
DR   Pfam; PF10396; TrmE_N; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   4: Predicted;
DR   PRODOM; C0H4V2.
DR   SWISS-2DPAGE; C0H4V2.
KW   Hydrolase {ECO:0000313|EMBL:CAX64129.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001450};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          163..420
FT                   /note="TrmE_N"
FT                   /evidence="ECO:0000259|Pfam:PF10396"
FT   DOMAIN          423..827
FT                   /note="MnmE_helical"
FT                   /evidence="ECO:0000259|Pfam:PF12631"
FT   DOMAIN          523..646
FT                   /note="G"
FT                   /evidence="ECO:0000259|Pfam:PF01926"
SQ   SEQUENCE   830 AA;  97942 MW;  E22A757DA0B6F4D7 CRC64;
     MIKRPFVHFV LLKCITVTLF LFIIFVDTFK GKRRNKPKRF PFFIPLKIMK CRKEMHLIKS
     KIGNRKMFEQ KENILSLNME EESFIDKNEQ NKECEKKNMD INTIHNFLVN NNFASNEDEK
     KKNICDNIST YYSEANNNMI NYVTNYDDVR KEYLLKIMSD KETIYALSSG NVQSAISVIR
     ISGPLSKMIL EILLHKGKDK KIKINNNNNN NNNNKNNICY NNYGKRQHFK KDNINRICNE
     KRTTNDVYNL SYETSGNEKL GDYNLHDIIH MRKNLEERKL YMGKLYDKNN DIIDIVMYSY
     FKEPKSYTGE ELVEIYCHGN MLIVKEIMSA INNMNELFYK IIIEERQNNI YNNDMLCSFI
     EDNNNNNNNN TKYDTNEGNN NPTNDHIIYE KIHERCHHNF IKIRESYKGE FTRRAFENNK
     MSLLQIEGLK ELLFCKQKVQ KQIALNYMNG YAKDIYLKLK ELLKELLVYT ELKIDFEEEH
     ITSPKEKEEI QNMVLRKIRE AINHINYILK KNNVEDISNS FDILLFGNVN SGKSTLMNNI
     CNNDISIVTN IKGSTLDIIQ KNIQIFNNSY NLCDSAGVIK SEKIKSLNEK NYILYEKKKK
     KKKNIHKTLE SMGIKKTLSF LKNNCISAFV LLNIKNYKKE LINIIKILNH NFKGKINQEN
     NKGELNKNKM TNKIKIPYFI FCLNKCDLVS TCKFSKIKRN VKKCLLANLS THILKRCSKK
     IFFISSKNGY NIDTLLKYFN EKMIKKRKLL FDKKYSNGNN IMFLPFERHK LYLKKAINHL
     LFIQKNIHNL TFDIISEEIK LAVNSLNRII GTIKNEQILN KILDSFCIGK
//

If you have problems or comments...

PBIL Back to PBIL home page