(data stored in ACNUC9543 zone)

SWISSPROT: C0H4V6_PLAF7

ID   C0H4V6_PLAF7            Unreviewed;       262 AA.
AC   C0H4V6;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   08-MAY-2019, entry version 68.
DE   SubName: Full=14-3-3 protein {ECO:0000313|EMBL:CAX64133.1};
GN   ORFNames=PF3D7_0818200 {ECO:0000313|EMBL:CAX64133.1};
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329 {ECO:0000313|EMBL:CAX64133.1, ECO:0000313|Proteomes:UP000001450};
RN   [1] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.,
RA   Eisen J.A., Rutherford K., Salzberg S.L., Craig A., Kyes S.,
RA   Chan M.S., Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S.,
RA   Pertea M., Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B.,
RA   Martin D.M., Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A.,
RA   McFadden G.I., Cummings L.M., Subramanian G.M., Mungall C.,
RA   Venter J.C., Carucci D.J., Hoffman S.L., Newbold C., Davis R.W.,
RA   Fraser C.M., Barrell B.;
RT   "Genome sequence of the human malaria parasite Plasmodium
RT   falciparum.";
RL   Nature 419:498-511(2002).
RN   [2] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368867; DOI=10.1038/nature01095;
RA   Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA   Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA   Buckee C.O., Burrows C., Cherevach I., Chillingworth C.,
RA   Chillingworth T., Christodoulou Z., Clark L., Clark R., Corton C.,
RA   Cronin A., Davies R.M., Davis P., Dear P., Dearden F., Doggett J.,
RA   Feltwell T., Goble A., Goodhead I., Gwilliam R., Hamlin N., Hance Z.,
RA   Harper D., Hauser H., Hornsby T., Holroyd S., Horrocks P.,
RA   Humphray S., Jagels K., James K.D., Johnson D., Kerhornou A.,
RA   Knights A., Konfortov B., Kyes S., Larke N., Lawson D., Lennard N.,
RA   Line A., Maddison M., Mclean J., Mooney P., Moule S., Murphy L.,
RA   Oliver K., Ormond D., Price C., Quail M.A., Rabbinowitsch E.,
RA   Rajandream M.A., Rutter S., Rutherford K.M., Sanders M., Simmonds M.,
RA   Seeger K., Sharp S., Smith R., Squares R., Squares S., Stevens K.,
RA   Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA   Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT   "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL   Nature 419:527-531(2002).
CC   -!- SIMILARITY: Belongs to the 14-3-3 family.
CC       {ECO:0000256|RuleBase:RU003466, ECO:0000256|SAAS:SAAS00595241}.
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DR   EMBL; AL844507; CAX64133.1; -; Genomic_DNA.
DR   RefSeq; XP_002808856.1; XM_002808810.1.
DR   SMR; C0H4V6; -.
DR   IntAct; C0H4V6; 1.
DR   DrugBank; DB11638; Artenimol.
DR   TCDB; 8.A.98.1.3; the 14-3-3 protein (14-3-3) family.
DR   PRIDE; C0H4V6; -.
DR   EnsemblProtists; CAX64133; CAX64133; PF3D7_0818200.
DR   GeneDB; PF3D7_0818200.1:pep; -.
DR   GeneID; 2655418; -.
DR   KEGG; pfa:PF3D7_0818200; -.
DR   EuPathDB; PlasmoDB:PF3D7_0818200; -.
DR   HOGENOM; HOG000240379; -.
DR   InParanoid; C0H4V6; -.
DR   KO; K06630; -.
DR   OMA; MKEHEKG; -.
DR   PhylomeDB; C0H4V6; -.
DR   Reactome; R-PFA-3769402; Deactivation of the beta-catenin transactivating complex.
DR   Reactome; R-PFA-6804114; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest.
DR   Proteomes; UP000001450; Chromosome 8.
DR   GO; GO:0005737; C:cytoplasm; IDA:GeneDB.
DR   GO; GO:0020020; C:food vacuole; IEA:GeneDB.
DR   GO; GO:0005634; C:nucleus; IDA:GeneDB.
DR   GO; GO:0042393; F:histone binding; IDA:GeneDB.
DR   GO; GO:0019904; F:protein domain specific binding; IEA:InterPro.
DR   Gene3D; 1.20.190.20; -; 1.
DR   InterPro; IPR000308; 14-3-3.
DR   InterPro; IPR023409; 14-3-3_CS.
DR   InterPro; IPR036815; 14-3-3_dom_sf.
DR   InterPro; IPR023410; 14-3-3_domain.
DR   PANTHER; PTHR18860; PTHR18860; 1.
DR   Pfam; PF00244; 14-3-3; 1.
DR   PIRSF; PIRSF000868; 14-3-3; 1.
DR   PRINTS; PR00305; 1433ZETA.
DR   SMART; SM00101; 14_3_3; 1.
DR   SUPFAM; SSF48445; SSF48445; 1.
DR   PROSITE; PS00796; 1433_1; 1.
DR   PROSITE; PS00797; 1433_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; C0H4V6.
DR   SWISS-2DPAGE; C0H4V6.
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001450};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001450}.
FT   DOMAIN       11    257       14_3_3. {ECO:0000259|SMART:SM00101}.
FT   COILED       20     40       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   262 AA;  30193 MW;  78CF3EE38425D91A CRC64;
     MATSEELKQL RCDCTYRSKL AEQAERYDEM ADAMRTLVEQ CVNNDKDELT VEERNLLSVA
     YKNAVGARRA SWRIISSVEQ KEMSKANVHN KNVAATYRKK VEEELNNICQ DILNLLTKKL
     IPNTSESESK VFYYKMKGDY YRYISEFSCD EGKKEASNCA QEAYQKATDI AENELPSTHP
     IRLGLALNYS VFFYEILNQP HQACEMAKRA FDDAITEFDN VSEDSYKDST LIMQLLRDNL
     TLWTSDLQGD QTEEKSKDEG LE
//

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