(data stored in SCRATCH zone)

SWISSPROT: C0H4X0_PLAF7

ID   C0H4X0_PLAF7            Unreviewed;       924 AA.
AC   C0H4X0;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   11-DEC-2019, entry version 63.
DE   SubName: Full=Thrombospondin-related protein 1, putative {ECO:0000313|EMBL:CAX64148.1};
GN   ORFNames=PF3D7_0822700 {ECO:0000313|EMBL:CAX64148.1};
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329 {ECO:0000313|EMBL:CAX64148.1, ECO:0000313|Proteomes:UP000001450};
RN   [1] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D.,
RA   Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S.,
RA   Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA   Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A.,
RA   Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA   Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA   Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G.;
RT   "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL   Nature 419:498-511(2002).
RN   [2] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368867; DOI=10.1038/nature01095;
RA   Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA   Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA   Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T.,
RA   Christodoulou Z., Clark L., Clark R., Corton C., Cronin A., Davies R.M.,
RA   Davis P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A.,
RA   Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H.,
RA   Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James K.D.,
RA   Johnson D., Kerhornou A., Knights A., Konfortov B., Kyes S., Larke N.,
RA   Lawson D., Lennard N., Line A., Maddison M., Mclean J., Mooney P.,
RA   Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A.,
RA   Rabbinowitsch E., Rajandream M.A., Rutter S., Rutherford K.M., Sanders M.,
RA   Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S.,
RA   Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA   Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT   "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL   Nature 419:527-531(2002).
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DR   EMBL; AL844507; CAX64148.1; -; Genomic_DNA.
DR   RefSeq; XP_002808870.1; XM_002808824.1.
DR   EnsemblProtists; CAX64148; CAX64148; PF3D7_0822700.
DR   GeneDB; PF3D7_0822700.1:pep; -.
DR   GeneID; 2655386; -.
DR   KEGG; pfa:PF3D7_0822700; -.
DR   EuPathDB; PlasmoDB:PF3D7_0822700; -.
DR   InParanoid; C0H4X0; -.
DR   OMA; KKDDETC; -.
DR   Proteomes; UP000001450; Chromosome 8.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0015086; F:cadmium ion transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0008324; F:cation transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015341; F:zinc efflux active transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0006876; P:cellular cadmium ion homeostasis; IBA:GO_Central.
DR   GO; GO:0006879; P:cellular iron ion homeostasis; IBA:GO_Central.
DR   GO; GO:0006882; P:cellular zinc ion homeostasis; IBA:GO_Central.
DR   Gene3D; 2.20.100.10; -; 1.
DR   InterPro; IPR000884; TSP1_rpt.
DR   InterPro; IPR036383; TSP1_rpt_sf.
DR   SUPFAM; SSF82895; SSF82895; 1.
DR   PROSITE; PS50092; TSP1; 1.
PE   4: Predicted;
DR   PRODOM; C0H4X0.
DR   SWISS-2DPAGE; C0H4X0.
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001450};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        883..905
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          105..162
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   924 AA;  111517 MW;  C7EBBFEB9CA43B43 CRC64;
     MYNHFLYFPF EKFLFIFILV VWLAFQTNKR PSYITKKYKI DDVKNIDMII QHDIVINTQN
     IMCIFYILYI NNLDKNKNFI QYKNFKKNKS YKYKNNNNNI IIINSHSHSN SHSNSHSHSN
     SHSNSHSHSN SHSNSHSHSN SHSHSHSNSH SNSHSHSSTQ NSLYHDTNQA NFLKPTSFFL
     YKHHVYFNQK YKKDPNILNK LKVPRNHIFH INKCDLNYYI QNYEFFFFFP DYYEYSHLYI
     RLDKLFYFQR CGCDTNIKKT KKRNQNIFNN MLGMKEKDTY LQNEICDIYW NYLKDDNTYD
     KYNFSIINYI KNIIKKMYRY LYIYKVFVLK QFYRIVYYNQ GIRNFYYMLF SYIYNKGSII
     YNYNQMYFKK HRKKQTIIRS KRFMNEHIKE EDVDYNIVKD EKDKSIQSTE QKSYLKNNTI
     QYFQCFLDKA MENKNAENEL DKWIDPQSKS CYCSEEFAEP CTSEDLVDIN NINQIMDNAF
     CEYNNNDNNN NDNNKNNNNN INNIINIYDN NILGDNVKNI FVALSEYKIL QCNDKEKKDI
     IKKEQLYNYC KYGLNIWDNK NMYDYLNCLN VISYNKKDDK TCIRKCENIK KLCNIVAQFY
     SFEVCKKYYE NNKHTEDIYI NNFKYFSDHC KYIDPTNRGL VLCKHKNVEC VYSQWSEWST
     CSKTCIENEY DTNSTRTRTR ILLNKFEVPS KSCSFIINEK NNLMDINFCS YLPFCNKNND
     MKKKDDERIM PFVISIKEIE KLNTLKYLNN DDNDLLNENY KNYESVHKNN ECKVTDMYQY
     EYAISYNEKN KSCSCPNNQS PCYFKDIYNS ESWKKSLHIL CKHNPHINVI TADYIIIDCN
     MSISIKKKEI AVNTYLAMTF NCHSDIFQYI FCAKNIQSIR TNFIYIIITC AFGFISAIYI
     IHIFINKWHI FKLLLHKQNK KKSY
//

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