(data stored in ACNUC9543 zone)

SWISSPROT: C0H4Z4_PLAF7

ID   C0H4Z4_PLAF7            Unreviewed;      1921 AA.
AC   C0H4Z4;
DT   05-MAY-2009, integrated into UniProtKB/TrEMBL.
DT   05-MAY-2009, sequence version 1.
DT   11-DEC-2019, entry version 53.
DE   SubName: Full=Surface-associated interspersed protein 8.1 (SURFIN 8.1) {ECO:0000313|EMBL:CAX64169.1};
GN   ORFNames=PF3D7_0831100 {ECO:0000313|EMBL:CAX64169.1};
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329 {ECO:0000313|EMBL:CAX64169.1, ECO:0000313|Proteomes:UP000001450};
RN   [1] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D.,
RA   Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S.,
RA   Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA   Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A.,
RA   Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA   Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA   Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G.;
RT   "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL   Nature 419:498-511(2002).
RN   [2] {ECO:0000313|Proteomes:UP000001450}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450};
RX   PubMed=12368867; DOI=10.1038/nature01095;
RA   Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA   Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA   Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T.,
RA   Christodoulou Z., Clark L., Clark R., Corton C., Cronin A., Davies R.M.,
RA   Davis P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A.,
RA   Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H.,
RA   Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James K.D.,
RA   Johnson D., Kerhornou A., Knights A., Konfortov B., Kyes S., Larke N.,
RA   Lawson D., Lennard N., Line A., Maddison M., Mclean J., Mooney P.,
RA   Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A.,
RA   Rabbinowitsch E., Rajandream M.A., Rutter S., Rutherford K.M., Sanders M.,
RA   Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S.,
RA   Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA   Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT   "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL   Nature 419:527-531(2002).
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DR   EMBL; AL844507; CAX64169.1; -; Genomic_DNA.
DR   RefSeq; XP_002808891.1; XM_002808845.1.
DR   EnsemblProtists; CAX64169; CAX64169; PF3D7_0831100.
DR   GeneDB; PF3D7_0831100.1:pep; -.
DR   GeneID; 2655214; -.
DR   KEGG; pfa:PF3D7_0831100; -.
DR   EuPathDB; PlasmoDB:PF3D7_0831100; -.
DR   HOGENOM; HOG000148373; -.
DR   InParanoid; C0H4Z4; -.
DR   OMA; NESHLEH; -.
DR   PhylomeDB; C0H4Z4; -.
DR   Proteomes; UP000001450; Chromosome 8.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR024288; SICA_C.
DR   Pfam; PF12879; SICA_C; 3.
PE   4: Predicted;
DR   PRODOM; C0H4Z4.
DR   SWISS-2DPAGE; C0H4Z4.
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001450};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        343..362
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          425..484
FT                   /note="SICA_C"
FT                   /evidence="ECO:0000259|Pfam:PF12879"
FT   DOMAIN          817..865
FT                   /note="SICA_C"
FT                   /evidence="ECO:0000259|Pfam:PF12879"
FT   DOMAIN          1200..1267
FT                   /note="SICA_C"
FT                   /evidence="ECO:0000259|Pfam:PF12879"
FT   REGION          215..242
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          117..137
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          392..412
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          669..689
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1589..1623
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        215..230
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1921 AA;  236183 MW;  5DE5E8457055D3B0 CRC64;
     MAIISSIPNY RKGLNPSLYN LRFSLFRDRV NAYTISKIKK LKKSRNYKRL CRYLNYKLDD
     IKDVFMLNNV LGIPRTARMG LWENVMENKL KDIIEENSDN KCRRIYPYFQ RIQRRRRKAL
     ENFCEDKEKK QEELKNVKFD MKKCLEFNEW VKESENKIFK LFKNNITERD KRKKAYIISD
     KCKLGNLNTL FGQMDCSDKI DRHFPYIFLE GNPVYPSEKD DDKNIKDPEE GKDEEEEEED
     GEVTINIRSN GEKGFRFVNN TLVLEGIEGS GFDLDFETYD ISPHSLNSGE IANLFEFNNE
     SHLEHMNIES NRSPNMVDID FSDVPLTAAH MTSSITAKNI SSYLYVPLGV LFIIISFIWF
     FLNRTKHLNM LIKEKEKVKT ENIVPSEAYV KLDDLEVMSE EIKEKQKEKL KKKIHAQKKL
     EIIEDPYKIK LLERKKWLWK TIIEIHMLIL EEQRKAEWEF NKGDFLNICI DEFSNQEKKP
     DTNIITSDLP FDEPEVIETI RMMNKQSDIW YRWVERHAHM LEKWKEEEWF LRLKESWKDE
     EEEYMKRAYK ELLISLRGDK YHMSQRQKII WRKWIAKHPY RIREFVIDKW FNQLFEELEK
     EGIISDEAIR NFLSQYEEAY DEEKIQEFIK YKKKVLVVIL WIKIYMSMLE EYVKEEDIES
     EKLFIDTSLE ELKKKKEIEE EVLEDLKKDI YESDEMKEIE KYKGEDWFKQ MQQDWIRRDY
     KFVSSYNLES DDEEQFHEFV KKPTVEIQKD LLKEQWKNIE LKWIEEDNYD EYVLEDELLK
     ETKYIKPKDK MKHRIIKEDN IYGEQLKVFD EIEKRSIYLS SKRVLKWKTI IEIHLEVLHD
     CKKEEWDKNK RDFLNICIEE LVKGQNEDKK NKENYNYITN ESDNYDIVEY TKSFCNTWKD
     RHNYMLEKWN KENWFVQLKN DWVEEQNEYM RKTYKELLIS LKGDKYNMSQ RQKIIWRKWI
     AKHPYKINEE IINIWLNRLS DERDKNGIIS DEAIKKFLSL EKDISDKDFL KYRRKKLEVI
     LWVKIYMSVL EEEKNEELEK SKESFLNTCI DELKKEEYSE ENERMITIVD EMKKGFRICD
     KVEDYKKKKW KNEEWYKDLK KEWIKEEDKY IDSIYLMKKD EIYEDDLLNK SIVELEKSVS
     LKHWKDMYIK WIDEDNERDW LRIAIDKKNL KTDEINEDIN RMIELNMLED YSNDLYDKKK
     IKWKTIIEIH MEVLNDCKND EWEMNKGDFL DICLEEFGTM ENKEYSHIIN NMLMVGELEY
     KHLNMDVIER QNDLWNKWIE GHRYMLEKWK KEKWFIVLKE NWKNEEHKYM RKAYLELLMS
     LREDVKNPLL QRQKIIWRKW IAKNLYHIES NVIKKWFDTL LEEIERKGVI ELDGCINLIE
     MEENEEYLEY LKEYRKKKLI CIIWIKIYMM IIEEHKKEEY LECKEIFLDT CVDELREQEI
     LEGNELYMDD MKTSILLNDQ KEEIEKLKMK KWYKDLKKEW IIEENRYFRS IINEEDDEEY
     KNMISKPLRD VEKKISKKHW EDIQLKWIDE DNERDWLKIA RNENEEIKYL YINENVSKKK
     KKVPFYIDDY RKKGRSNKNK IYRRKREKCN VKLNENNTMN KEMENWENRM EFLKICVDLL
     KKRTFYYINI WEKNKAFYDE TNEIMKQLEE KIFERQKILW YNKEDMNKMS SKKWGNEEWF
     IILKNDWNEE KTCYLNGIQY EYNINNLIEE EKKYLYLKKE KIIWKEWLLK NFKNIEECDN
     EDWFNNLMET YKIDEICTIN MNGEIHSLGL ENTLKRNFLK NIIWIDIFMG VLNACEEEEE
     LEEHKHKNML ESKVEDNDKL FYEKNEDYIN KNEMENYIND IQENEGNQMD IPDWFDAYQS
     DEMSGKQKSI QKDEQWFIKE LEEGGIKSDV LQENYTIYNN KLIEQKMNIL RESYIRNQND
     T
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