(data stored in ACNUC16935 zone)

SWISSPROT: Q5ARR6_EMENI

ID   Q5ARR6_EMENI            Unreviewed;       323 AA.
AC   Q5ARR6; C8VKY7;
DT   26-APR-2005, integrated into UniProtKB/TrEMBL.
DT   26-APR-2005, sequence version 1.
DT   30-AUG-2017, entry version 89.
DE   SubName: Full=FMN-dependent dehydrogenase family protein (AFU_orthologue AFUA_8G02300) {ECO:0000313|EMBL:CBF84460.1};
GN   ORFNames=ANIA_09014 {ECO:0000313|EMBL:CBF84460.1};
OS   Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL
OS   194 / M139) (Aspergillus nidulans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=227321 {ECO:0000313|EMBL:CBF84460.1, ECO:0000313|Proteomes:UP000000560};
RN   [1] {ECO:0000313|Proteomes:UP000000560}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139
RC   {ECO:0000313|Proteomes:UP000000560};
RX   PubMed=16372000; DOI=10.1038/nature04341;
RA   Galagan J.E., Calvo S.E., Cuomo C., Ma L.J., Wortman J.R.,
RA   Batzoglou S., Lee S.I., Basturkmen M., Spevak C.C., Clutterbuck J.,
RA   Kapitonov V., Jurka J., Scazzocchio C., Farman M., Butler J.,
RA   Purcell S., Harris S., Braus G.H., Draht O., Busch S., D'Enfert C.,
RA   Bouchier C., Goldman G.H., Bell-Pedersen D., Griffiths-Jones S.,
RA   Doonan J.H., Yu J., Vienken K., Pain A., Freitag M., Selker E.U.,
RA   Archer D.B., Penalva M.A., Oakley B.R., Momany M., Tanaka T.,
RA   Kumagai T., Asai K., Machida M., Nierman W.C., Denning D.W.,
RA   Caddick M., Hynes M., Paoletti M., Fischer R., Miller B., Dyer P.,
RA   Sachs M.S., Osmani S.A., Birren B.W.;
RT   "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT   fumigatus and A. oryzae.";
RL   Nature 438:1105-1115(2005).
RN   [2] {ECO:0000313|Proteomes:UP000000560}
RP   GENOME REANNOTATION.
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139
RC   {ECO:0000313|Proteomes:UP000000560};
RX   PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA   Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA   Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P.,
RA   von Dohren H., Doonan J., Driessen A.J., Durek P., Espeso E.,
RA   Fekete E., Flipphi M., Estrada C.G., Geysens S., Goldman G.,
RA   de Groot P.W., Hansen K., Harris S.D., Heinekamp T., Helmstaedt K.,
RA   Henrissat B., Hofmann G., Homan T., Horio T., Horiuchi H., James S.,
RA   Jones M., Karaffa L., Karanyi Z., Kato M., Keller N., Kelly D.E.,
RA   Kiel J.A., Kim J.M., van der Klei I.J., Klis F.M., Kovalchuk A.,
RA   Krasevec N., Kubicek C.P., Liu B., Maccabe A., Meyer V., Mirabito P.,
RA   Miskei M., Mos M., Mullins J., Nelson D.R., Nielsen J., Oakley B.R.,
RA   Osmani S.A., Pakula T., Paszewski A., Paulsen I., Pilsyk S., Pocsi I.,
RA   Punt P.J., Ram A.F., Ren Q., Robellet X., Robson G., Seiboth B.,
RA   van Solingen P., Specht T., Sun J., Taheri-Talesh N., Takeshita N.,
RA   Ussery D., vanKuyk P.A., Visser H., van de Vondervoort P.J.,
RA   de Vries R.P., Walton J., Xiang X., Xiong Y., Zeng A.P., Brandt B.W.,
RA   Cornell M.J., van den Hondel C.A., Visser J., Oliver S.G., Turner G.;
RT   "The 2008 update of the Aspergillus nidulans genome annotation: a
RT   community effort.";
RL   Fungal Genet. Biol. 46:S2-13(2009).
CC   -!- COFACTOR:
CC       Name=FMN; Xref=ChEBI:CHEBI:58210; Evidence={ECO:0000256|PROSITE-
CC         ProRule:PRU00683};
CC   -!- SIMILARITY: Belongs to the FMN-dependent alpha-hydroxy acid
CC       dehydrogenase family. {ECO:0000256|PROSITE-ProRule:PRU00683}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00683}.
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DR   EMBL; BN001307; CBF84460.1; -; Genomic_DNA.
DR   RefSeq; XP_682283.1; XM_677191.1.
DR   STRING; 162425.CADANIAP00007840; -.
DR   EnsemblFungi; CADANIAT00007840; CADANIAP00007840; CADANIAG00007840.
DR   EnsemblFungi; EAA64346; EAA64346; AN9014.2.
DR   GeneID; 2868255; -.
DR   KEGG; ani:AN9014.2; -.
DR   HOGENOM; HOG000217463; -.
DR   KO; K11517; -.
DR   OMA; DTPGFFQ; -.
DR   OrthoDB; EOG092C2PU6; -.
DR   Proteomes; UP000000560; Chromosome VII.
DR   GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd02809; alpha_hydroxyacid_oxid_FMN; 1.
DR   Gene3D; 3.20.20.70; -; 2.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR012133; Alpha-hydoxy_acid_DH_FMN.
DR   InterPro; IPR000262; FMN-dep_DH.
DR   InterPro; IPR008259; FMN_hydac_DH_AS.
DR   Pfam; PF01070; FMN_dh; 2.
DR   PIRSF; PIRSF000138; Al-hdrx_acd_dh; 2.
DR   PROSITE; PS00557; FMN_HYDROXY_ACID_DH_1; 1.
DR   PROSITE; PS51349; FMN_HYDROXY_ACID_DH_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q5ARR6.
DR   SWISS-2DPAGE; Q5ARR6.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000560};
KW   Flavoprotein {ECO:0000256|PROSITE-ProRule:PRU00683};
KW   FMN {ECO:0000256|PROSITE-ProRule:PRU00683};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000560}.
FT   NP_BIND     242    266       FMN. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00683}.
FT   ACT_SITE    211    211       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR000138-1, ECO:0000256|PROSITE-
FT                                ProRule:PRU00683}.
FT   BINDING      32     32       Substrate. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00683}.
FT   BINDING     114    114       FMN. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00683}.
FT   BINDING     136    136       FMN. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00683}.
FT   BINDING     187    187       FMN. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00683}.
FT   BINDING     214    214       Substrate. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00683}.
SQ   SEQUENCE   323 AA;  35123 MW;  68AE3EF620120E52 CRC64;
     MAHRGESFHK DVSCIADLKA LGSSRLPATS DYYNEGAMDL ITLRDNEAAF DRYKILPRVL
     INVAKVDTST EILGTKVSLP FGFSPAASQK LAHPDGELAT SRAAANFGIC MGLSSYSNYS
     LEDVAAQGMG NPYVMQMCVL RDRSITLQLL QRAENAPNRP SLPDPSLDWA STIPWLREHT
     SMQIWLKGVC SPADVELAIH YGVDGIVISN HGGRQLDGVP ATLDSLRLCA EVAKGRIPLA
     IDGGIRRGSD IFKALALGAR YCFMGRIPIW GLAYNGQEGV ELAIKILRQE LRVTMALAGC
     QTISEIRESH LSVLQPDGRL SKL
//

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