(data stored in ACNUC16935 zone)

SWISSPROT: PHOG_EMENI

ID   PHOG_EMENI              Reviewed;         566 AA.
AC   Q05534; C8VM27; Q5BDG6;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   16-NOV-2011, sequence version 3.
DT   07-JUN-2017, entry version 101.
DE   RecName: Full=Protein pacG;
DE   AltName: Full=Nonrepressible acid phosphatase regulator pacG;
GN   Name=pacG; ORFNames=AN1414;
OS   Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL
OS   194 / M139) (Aspergillus nidulans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=227321;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=16372000; DOI=10.1038/nature04341;
RA   Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R.,
RA   Batzoglou S., Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J.,
RA   Kapitonov V., Jurka J., Scazzocchio C., Farman M.L., Butler J.,
RA   Purcell S., Harris S., Braus G.H., Draht O., Busch S., D'Enfert C.,
RA   Bouchier C., Goldman G.H., Bell-Pedersen D., Griffiths-Jones S.,
RA   Doonan J.H., Yu J., Vienken K., Pain A., Freitag M., Selker E.U.,
RA   Archer D.B., Penalva M.A., Oakley B.R., Momany M., Tanaka T.,
RA   Kumagai T., Asai K., Machida M., Nierman W.C., Denning D.W.,
RA   Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L.,
RA   Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
RT   "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT   fumigatus and A. oryzae.";
RL   Nature 438:1105-1115(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA   Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA   Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P.,
RA   von Dohren H., Doonan J., Driessen A.J., Durek P., Espeso E.,
RA   Fekete E., Flipphi M., Estrada C.G., Geysens S., Goldman G.,
RA   de Groot P.W., Hansen K., Harris S.D., Heinekamp T., Helmstaedt K.,
RA   Henrissat B., Hofmann G., Homan T., Horio T., Horiuchi H., James S.,
RA   Jones M., Karaffa L., Karanyi Z., Kato M., Keller N., Kelly D.E.,
RA   Kiel J.A., Kim J.M., van der Klei I.J., Klis F.M., Kovalchuk A.,
RA   Krasevec N., Kubicek C.P., Liu B., Maccabe A., Meyer V., Mirabito P.,
RA   Miskei M., Mos M., Mullins J., Nelson D.R., Nielsen J., Oakley B.R.,
RA   Osmani S.A., Pakula T., Paszewski A., Paulsen I., Pilsyk S., Pocsi I.,
RA   Punt P.J., Ram A.F., Ren Q., Robellet X., Robson G., Seiboth B.,
RA   van Solingen P., Specht T., Sun J., Taheri-Talesh N., Takeshita N.,
RA   Ussery D., vanKuyk P.A., Visser H., van de Vondervoort P.J.,
RA   de Vries R.P., Walton J., Xiang X., Xiong Y., Zeng A.P., Brandt B.W.,
RA   Cornell M.J., van den Hondel C.A., Visser J., Oliver S.G., Turner G.;
RT   "The 2008 update of the Aspergillus nidulans genome annotation: a
RT   community effort.";
RL   Fungal Genet. Biol. 46:S2-13(2009).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 132-461.
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=7916713; DOI=10.1016/0378-1119(93)90426-4;
RA   Macrae W.D., Buxton F.P., Sibley S., Garven S., Gwynne D.I.,
RA   Arst H.N. Jr., Davies R.W.;
RT   "Characterization of an Aspergillus nidulans genomic DNA fragment
RT   conferring phosphate-non-repressible acid-phosphatase activity.";
RL   Gene 130:247-251(1993).
CC   -!- FUNCTION: Transcription factor that acts as a positive regulator
CC       of nonrepressible acid phosphatase activity. Is a major regulator
CC       of responses to nitrogen and carbon starvation and is essential
CC       for the expression of genes involved in vegetative incompatibility
CC       (like pin-c, het-6, and tol). Vegetative incompatibility is a non-
CC       self-recognition system ubiquitous in filamentous fungi which
CC       results in programmed cell death (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus. Cytoplasm {ECO:0000250}.
CC   -!- CAUTION: Was originally thought to be a phosphatase.
CC       {ECO:0000305|PubMed:7916713}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CBF84810.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=EAA64544.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
DR   EMBL; AACD01000022; EAA64544.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; BN001307; CBF84810.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; M96993; AAA33289.1; -; Genomic_DNA.
DR   PIR; JN0783; JN0783.
DR   RefSeq; XP_659018.1; XM_653926.1.
DR   PRIDE; Q05534; -.
DR   EnsemblFungi; CADANIAT00008025; CADANIAP00008025; CADANIAG00008025.
DR   EnsemblFungi; EAA64544; EAA64544; AN1414.2.
DR   GeneID; 2875501; -.
DR   KEGG; ani:AN1414.2; -.
DR   HOGENOM; HOG000157088; -.
DR   InParanoid; Q05534; -.
DR   OrthoDB; EOG092C3Q5X; -.
DR   Proteomes; UP000000560; Chromosome VII.
DR   Proteomes; UP000005890; Partially assembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000228; C:nuclear chromosome; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:transcription factor activity, sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:GO_Central.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1390; -; 1.
DR   InterPro; IPR024061; NDT80_DNA-bd_dom.
DR   InterPro; IPR008967; p53-like_TF_DNA-bd.
DR   Pfam; PF05224; NDT80_PhoG; 1.
DR   SUPFAM; SSF49417; SSF49417; 1.
DR   PROSITE; PS51517; NDT80; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q05534.
DR   SWISS-2DPAGE; Q05534.
KW   Complete proteome; Cytoplasm; DNA-binding; Nucleus;
KW   Reference proteome; Transcription; Transcription regulation.
FT   CHAIN         1    566       Protein pacG.
FT                                /FTId=PRO_0000023977.
FT   DNA_BIND     79    326       NDT80. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00850}.
FT   CONFLICT    376    376       G -> R (in Ref. 3; AAA33289).
FT                                {ECO:0000305}.
FT   CONFLICT    423    423       R -> L (in Ref. 3; AAA33289).
FT                                {ECO:0000305}.
FT   CONFLICT    447    447       G -> C (in Ref. 3; AAA33289).
FT                                {ECO:0000305}.
FT   CONFLICT    451    451       P -> S (in Ref. 3; AAA33289).
FT                                {ECO:0000305}.
FT   CONFLICT    460    461       AS -> VV (in Ref. 3; AAA33289).
FT                                {ECO:0000305}.
SQ   SEQUENCE   566 AA;  61871 MW;  9BC5AB22BCDC665E CRC64;
     MEGFDTMALP YLASPLSLGN MQGTDYLNAL QGMDLPDQRS NFDSETFVSG DDLTFAHLSP
     QTLKRFSSGY EDSFPEMVTS FDPPPPAEPP ADSSIDHNNK LLSFSMPVYP WTLLDYSFRR
     ASISISAQLH GMFFLAESPW TTSPTENAPP QQGAELTCYR RNLFQITGSV TLPRALRYII
     TDTGDRIPIV AHELTVSATE SVEGNSVKII SVPWKTPAAN DAGKDTGNSS NTAAKVEKEP
     PAIPLDMLTG QDLDADYATF PIAWKRLQFR VATANNGRRK ELQQHFVVRL RVVATLSTGM
     KTPICEVHSG PVIVRGRSPR NFQSRKDLPL SGSAAASRKN AQAAAASNNL TRTSPSLTDK
     AKTVVKSSSP ETSSNGVPQQ SPPNWALATN STLPPPTTTT LPHSSVYSQS SPEFSRPVEA
     HRRTTSAIAA PINLSLLDDD SLNLSNGDSR PHTSFSNDLA SKSLSVDSGR PVKMRKVSHS
     MPQAQSRSTS ATFLNTANFQ QMLPVPFTSE SADVLYEYFP LGLEDWQGPV DAVYRPHVVH
     HTNMPQMKYI TARGQSKRYF AAEDVF
//

If you have problems or comments...

PBIL Back to PBIL home page