(data stored in ACNUC16935 zone)

SWISSPROT: NOP12_EMENI

ID   NOP12_EMENI             Reviewed;         520 AA.
AC   Q5BDC8; C8VMB9;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   26-APR-2005, sequence version 1.
DT   05-JUL-2017, entry version 76.
DE   RecName: Full=Nucleolar protein 12;
GN   Name=nop12; ORFNames=AN1452;
OS   Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL
OS   194 / M139) (Aspergillus nidulans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=227321;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=16372000; DOI=10.1038/nature04341;
RA   Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R.,
RA   Batzoglou S., Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J.,
RA   Kapitonov V., Jurka J., Scazzocchio C., Farman M.L., Butler J.,
RA   Purcell S., Harris S., Braus G.H., Draht O., Busch S., D'Enfert C.,
RA   Bouchier C., Goldman G.H., Bell-Pedersen D., Griffiths-Jones S.,
RA   Doonan J.H., Yu J., Vienken K., Pain A., Freitag M., Selker E.U.,
RA   Archer D.B., Penalva M.A., Oakley B.R., Momany M., Tanaka T.,
RA   Kumagai T., Asai K., Machida M., Nierman W.C., Denning D.W.,
RA   Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L.,
RA   Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
RT   "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT   fumigatus and A. oryzae.";
RL   Nature 438:1105-1115(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX   PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA   Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA   Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P.,
RA   von Dohren H., Doonan J., Driessen A.J., Durek P., Espeso E.,
RA   Fekete E., Flipphi M., Estrada C.G., Geysens S., Goldman G.,
RA   de Groot P.W., Hansen K., Harris S.D., Heinekamp T., Helmstaedt K.,
RA   Henrissat B., Hofmann G., Homan T., Horio T., Horiuchi H., James S.,
RA   Jones M., Karaffa L., Karanyi Z., Kato M., Keller N., Kelly D.E.,
RA   Kiel J.A., Kim J.M., van der Klei I.J., Klis F.M., Kovalchuk A.,
RA   Krasevec N., Kubicek C.P., Liu B., Maccabe A., Meyer V., Mirabito P.,
RA   Miskei M., Mos M., Mullins J., Nelson D.R., Nielsen J., Oakley B.R.,
RA   Osmani S.A., Pakula T., Paszewski A., Paulsen I., Pilsyk S., Pocsi I.,
RA   Punt P.J., Ram A.F., Ren Q., Robellet X., Robson G., Seiboth B.,
RA   van Solingen P., Specht T., Sun J., Taheri-Talesh N., Takeshita N.,
RA   Ussery D., vanKuyk P.A., Visser H., van de Vondervoort P.J.,
RA   de Vries R.P., Walton J., Xiang X., Xiong Y., Zeng A.P., Brandt B.W.,
RA   Cornell M.J., van den Hondel C.A., Visser J., Oliver S.G., Turner G.;
RT   "The 2008 update of the Aspergillus nidulans genome annotation: a
RT   community effort.";
RL   Fungal Genet. Biol. 46:S2-13(2009).
CC   -!- FUNCTION: Involved in pre-25S rRNA processing. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the RRM RBM34 family. {ECO:0000305}.
DR   EMBL; AACD01000022; EAA64582.1; -; Genomic_DNA.
DR   EMBL; BN001307; CBF84884.1; -; Genomic_DNA.
DR   RefSeq; XP_659056.1; XM_653964.1.
DR   ProteinModelPortal; Q5BDC8; -.
DR   STRING; 162425.CADANIAP00008065; -.
DR   EnsemblFungi; CADANIAT00008065; CADANIAP00008065; CADANIAG00008065.
DR   EnsemblFungi; EAA64582; EAA64582; AN1452.2.
DR   GeneID; 2875093; -.
DR   KEGG; ani:AN1452.2; -.
DR   HOGENOM; HOG000157415; -.
DR   InParanoid; Q5BDC8; -.
DR   KO; K14837; -.
DR   OMA; DIEEGLW; -.
DR   OrthoDB; EOG092C3SCB; -.
DR   Proteomes; UP000000560; Chromosome VII.
DR   Proteomes; UP000005890; Partially assembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   CDD; cd12669; RRM1_Nop12p_like; 1.
DR   InterPro; IPR034777; Nop12_RRM1.
DR   InterPro; IPR000504; RRM_dom.
DR   Pfam; PF00076; RRM_1; 1.
DR   SMART; SM00360; RRM; 2.
DR   SUPFAM; SSF54928; SSF54928; 2.
DR   PROSITE; PS50102; RRM; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q5BDC8.
DR   SWISS-2DPAGE; Q5BDC8.
KW   Complete proteome; Nucleus; Reference proteome; Repeat;
KW   Ribosome biogenesis; RNA-binding; rRNA processing.
FT   CHAIN         1    520       Nucleolar protein 12.
FT                                /FTId=PRO_0000081669.
FT   DOMAIN      191    303       RRM 1. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00176}.
FT   DOMAIN      311    421       RRM 2. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00176}.
SQ   SEQUENCE   520 AA;  56210 MW;  1F4DD073D74A88E0 CRC64;
     MGKKSKSQKE APATESAGSL PFLGGNVSVD PSLASLFEQS AGPVKVPEVP RLGAAPKTKI
     TDVEKDEEES SSAGNDSASE DQFMEDAPES PDAAEEAVQA VPEPPSRKRK RAAGEDLEES
     YMRRLAKEEQ KEQKKRRAER SSSLEEESED GEKESPQSED GESEDEGADI PKHEALAGAA
     NDDDELSKSN RTVFLGNVST KAITSKSAKK ELMKHLSSFL STLPESTGPH KIDSIRFRST
     AFASGGKIPK RAAFAKQEIH DDTTPSTNAY AVYSTAQAAK KAPAALNGTV VLDRHLRVDN
     VAHPAKVDHK RCVFVGNLDF IDNETGTEEG EKKKKNRPPA DVEEGLWRTF NAHTKASQSG
     PAGRGNVESV RVVRDRSTRV GKGFAYVQFY DQNCVEEALL LNDKRFPPLL PRKLRVVRAK
     KVAKKSVETT GAPKGSDRTL QGRAGKLLGR SSEARLKAAA KKSISQSSLV FEGNRATADG
     SSRIRVRTKS RGSKAKKDSR SKKRAAAYKA AGGKKAKIGK
//

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