(data stored in ACNUC16935 zone)

SWISSPROT: C8VMF3_EMENI

ID   C8VMF3_EMENI            Unreviewed;      2208 AA.
AC   C8VMF3;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   05-JUL-2017, entry version 54.
DE   SubName: Full=Pre-mRNA splicing helicase, putative (AFU_orthologue AFUA_8G04740) {ECO:0000313|EMBL:CBF84947.1};
GN   ORFNames=ANIA_10194 {ECO:0000313|EMBL:CBF84947.1};
OS   Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL
OS   194 / M139) (Aspergillus nidulans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=227321 {ECO:0000313|EMBL:CBF84947.1, ECO:0000313|Proteomes:UP000000560};
RN   [1] {ECO:0000313|Proteomes:UP000000560}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139
RC   {ECO:0000313|Proteomes:UP000000560};
RX   PubMed=16372000; DOI=10.1038/nature04341;
RA   Galagan J.E., Calvo S.E., Cuomo C., Ma L.J., Wortman J.R.,
RA   Batzoglou S., Lee S.I., Basturkmen M., Spevak C.C., Clutterbuck J.,
RA   Kapitonov V., Jurka J., Scazzocchio C., Farman M., Butler J.,
RA   Purcell S., Harris S., Braus G.H., Draht O., Busch S., D'Enfert C.,
RA   Bouchier C., Goldman G.H., Bell-Pedersen D., Griffiths-Jones S.,
RA   Doonan J.H., Yu J., Vienken K., Pain A., Freitag M., Selker E.U.,
RA   Archer D.B., Penalva M.A., Oakley B.R., Momany M., Tanaka T.,
RA   Kumagai T., Asai K., Machida M., Nierman W.C., Denning D.W.,
RA   Caddick M., Hynes M., Paoletti M., Fischer R., Miller B., Dyer P.,
RA   Sachs M.S., Osmani S.A., Birren B.W.;
RT   "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT   fumigatus and A. oryzae.";
RL   Nature 438:1105-1115(2005).
RN   [2] {ECO:0000313|Proteomes:UP000000560}
RP   GENOME REANNOTATION.
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139
RC   {ECO:0000313|Proteomes:UP000000560};
RX   PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA   Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA   Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P.,
RA   von Dohren H., Doonan J., Driessen A.J., Durek P., Espeso E.,
RA   Fekete E., Flipphi M., Estrada C.G., Geysens S., Goldman G.,
RA   de Groot P.W., Hansen K., Harris S.D., Heinekamp T., Helmstaedt K.,
RA   Henrissat B., Hofmann G., Homan T., Horio T., Horiuchi H., James S.,
RA   Jones M., Karaffa L., Karanyi Z., Kato M., Keller N., Kelly D.E.,
RA   Kiel J.A., Kim J.M., van der Klei I.J., Klis F.M., Kovalchuk A.,
RA   Krasevec N., Kubicek C.P., Liu B., Maccabe A., Meyer V., Mirabito P.,
RA   Miskei M., Mos M., Mullins J., Nelson D.R., Nielsen J., Oakley B.R.,
RA   Osmani S.A., Pakula T., Paszewski A., Paulsen I., Pilsyk S., Pocsi I.,
RA   Punt P.J., Ram A.F., Ren Q., Robellet X., Robson G., Seiboth B.,
RA   van Solingen P., Specht T., Sun J., Taheri-Talesh N., Takeshita N.,
RA   Ussery D., vanKuyk P.A., Visser H., van de Vondervoort P.J.,
RA   de Vries R.P., Walton J., Xiang X., Xiong Y., Zeng A.P., Brandt B.W.,
RA   Cornell M.J., van den Hondel C.A., Visser J., Oliver S.G., Turner G.;
RT   "The 2008 update of the Aspergillus nidulans genome annotation: a
RT   community effort.";
RL   Fungal Genet. Biol. 46:S2-13(2009).
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DR   EMBL; BN001307; CBF84947.1; -; Genomic_DNA.
DR   STRING; 162425.CADANIAP00008099; -.
DR   EnsemblFungi; CADANIAT00008099; CADANIAP00008099; CADANIAG00008099.
DR   InParanoid; C8VMF3; -.
DR   OMA; TLCKMID; -.
DR   OrthoDB; EOG092C01UD; -.
DR   Proteomes; UP000000560; Chromosome VII.
DR   GO; GO:0005829; C:cytosol; IEA:EnsemblFungi.
DR   GO; GO:0071014; C:post-mRNA release spliceosomal complex; IEA:EnsemblFungi.
DR   GO; GO:0005682; C:U5 snRNP; IEA:EnsemblFungi.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0000393; P:spliceosomal conformational changes to generate catalytic conformation; IEA:EnsemblFungi.
DR   Gene3D; 2.60.40.150; -; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR000008; C2_dom.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR004179; Sec63-dom.
DR   InterPro; IPR011991; WHTH_DNA-bd_dom.
DR   Pfam; PF00270; DEAD; 2.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF02889; Sec63; 2.
DR   SMART; SM00382; AAA; 2.
DR   SMART; SM00487; DEXDc; 2.
DR   SMART; SM00490; HELICc; 2.
DR   SMART; SM00973; Sec63; 2.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF52540; SSF52540; 5.
DR   SUPFAM; SSF81296; SSF81296; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 2.
DR   PROSITE; PS51194; HELICASE_CTER; 2.
PE   4: Predicted;
DR   PRODOM; C8VMF3.
DR   SWISS-2DPAGE; C8VMF3.
KW   ATP-binding {ECO:0000313|EMBL:CBF84947.1};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000560};
KW   Helicase {ECO:0000313|EMBL:CBF84947.1};
KW   Hydrolase {ECO:0000313|EMBL:CBF84947.1};
KW   Nucleotide-binding {ECO:0000313|EMBL:CBF84947.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000560}.
FT   DOMAIN      542    726       Helicase ATP-binding.
FT                                {ECO:0000259|PROSITE:PS51192}.
FT   DOMAIN      764    973       Helicase C-terminal.
FT                                {ECO:0000259|PROSITE:PS51194}.
FT   DOMAIN     1393   1569       Helicase ATP-binding.
FT                                {ECO:0000259|PROSITE:PS51192}.
FT   DOMAIN     1646   1801       Helicase C-terminal.
FT                                {ECO:0000259|PROSITE:PS51194}.
SQ   SEQUENCE   2208 AA;  249321 MW;  F479B4077A302EC3 CRC64;
     MADQNISQYK YSAMSNLVLQ ADRRFISRVN DEATGDPESL AGRISIREMG SRIARDDAPK
     SKKKAVGPVD IERGAIREGE DVLAREQKKR QKGQPAQLRG QGILSAADAL IEGLKYRPRT
     PATRATYDLI LTLTASRLGD VSHEVVRSAA DAVLEVLKDE EMKDFDKKRE IDDLLGTSLD
     PKEFNELVNL GKKITDYDAQ DEDEEMGDGV TGEDEAELDE RQGVAVVFDE DEDEDRMGTM
     DEIHDEDESD DEDEEQQESD SGEGAAKEAP EDLPTEEMVI DGGASADGEQ QKKGLIVSAR
     DIDAYWLQRQ IGAAYSDAHI QQEKATQALE IMEGKTEDGS PRSLRDVEND LMELFDYDFP
     DLVAKLVTNR DKVVWTTRWR RVAEDADARN LVESEMVEAG HRGILDEIRG KTVSRDNDSG
     RPEKRIKMDL MDVDLPKAPA AAEEKKTADG GLVRGLQPKR LINLENLVFH QGNHLMTNPN
     VKLPQGSTKR TFKGYEEIHV PQPKSKQEPG ERKVAISELP EWARIGFGDA KELNRIQTKC
     YPSAFQDDGN MLVCAPTGSG KTNVAMLSIL REVGKNRNSQ TGEIMLDDFK IVYISPLKAL
     VQEQVENFGR RLAPYGIKVA ELTGDRQLTK QQIAETQVIV TTPEKFDVIT RKASETSYTK
     LVRLIIIDEI HLLHDERGPV IESIVSRTIR QVEQTGDAVR IVGLSATLPN YRDVASFLRV
     DPAKGLFHFD GSYRPCPLKQ EFIGVTDKKP IKQLKIMNDI CYNKVIEHVG QNRNQMLIFV
     HSRKETAKTA KYLRDKALEM ETIGQILKSD SASRAILAEE AESVNDAALK DILPYGFGIH
     HAGLSLADRD SVQALFKDGS IQVLVCTATL AWGVNLPAHT VIIKGTQVYS PEKGSWVELS
     PQDVLQMLGR AGRPQYDTYG EGIIITTQAE IQYYLSLMNQ QLPIESQLVS KLADNMNAEI
     VLGNIRTRDE GVDWLGYTYL FVRMLRSPGL YSVGADYEND DALEQKRVDL VHSAAVLLEK
     AGLVKYDKKT GRLQSTELGR IASHYYIGHN SMLTYNQHLQ PSIGNIELFR IFALSDEFKY
     IPVRQDEKLE LAKMLGRVPV PVKEGIDEPH AKINVLLQAY ISRLKLEGLA LMADLVYVTQ
     SAGRILRALF EICLRRGWAS VAKNALDLCK MAERRMWPTM SPLRQFPRCP RDILQKSERI
     DVPWGSYFDL DPPRMGELLG MPRAGKTVCD LVSKFPRLEV QAQVQPITRS MLRVELTITP
     NFVWDEELHG TAQDFWIMVE DCDGEEILFH DQFVLRKDYA ESEMNEHLVE FTVPITEPMP
     PNYFISLVSD RWMHSETRIA VSFQKLILPE RFPPHTPLLD MQRAPVKALK RDEYQRLYPD
     WEYFNKIQTQ TFKTLFESDD NVFIGAPTGS GKTVCAELAI LRHWAKEDSG RAVYVAPFQE
     LIDSRLEDWK KRLSGLAGGK SIAKLTGEMT ADLKILAGSD LVLATPTQWD VLSRQWQKRK
     NVRAVELFVA DELHMLGGYG GYVYEVVVSR MHSIALQTES GMRIVGLSVP LSNARDIGEW
     IGASKHTIYN FSPHARPVPL ELHIQSFSIP HFPSLMLAMA RPAYLSILQL SADKPALIFV
     PNRKQTRATA IDLLTACSID DDEDRFLHAD IEELQPLLGR VHERTLAESL SHGIGYYHEA
     LSQTDKRIVS HLYNIGAIQV VIASRDVCWE LNLTGHLVVV MGTQFFEGRE HRYIDYPISE
     ILQMFGKASR PGQDKVGRGV LMVPTVKREY YKKFLNEALP VESHLQLYMH DAFVTEISQG
     TIASTQDSVD WLTYTYFYRR LLANPSFYGL TDISHEGLST FLSELVENTL KELSEAKIID
     LDEEDDSVSP LNAASIGAYY NISYITMQTF LLSLSARTKL KGILEIVTAA TEFESVQMRR
     HEEHILRRVY DRVPVKTSQV AFDSPHFKSF VLLQAHFSRM QLPIDLAKDQ EVIVSKALNL
     LSACVDILAS EGHMNAMNAM EMSQMVVQAM WDRDSPLKQI PHFGPEAIKV ANEYNINDIF
     EFMDAMDPSE NKDYNTLVKR LNLDNKQLAQ AAAFTNNKYP ILELDFEVED PENITAGEPA
     YLKIKVEREV DEDEEFDTTV HAPFYPGQKM ENWWLVVGDE KTRNLLAIKR VTIGRKLELR
     LDYTVPTPGE HELTLYLMCD SYVGVDQAPT FTVRAAEGME EDESEEEE
//

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