(data stored in ACNUC16935 zone)

SWISSPROT: Q5BD56_EMENI

ID   Q5BD56_EMENI            Unreviewed;       334 AA.
AC   Q5BD56; C8VMQ8;
DT   26-APR-2005, integrated into UniProtKB/TrEMBL.
DT   26-APR-2005, sequence version 1.
DT   05-JUL-2017, entry version 89.
DE   SubName: Full=Methylenetetrahydrofolate dehydrogenase (AFU_orthologue AFUA_8G05330) {ECO:0000313|EMBL:CBF85042.1};
GN   ORFNames=ANIA_01524 {ECO:0000313|EMBL:CBF85042.1};
OS   Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL
OS   194 / M139) (Aspergillus nidulans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=227321 {ECO:0000313|EMBL:CBF85042.1, ECO:0000313|Proteomes:UP000000560};
RN   [1] {ECO:0000313|Proteomes:UP000000560}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139
RC   {ECO:0000313|Proteomes:UP000000560};
RX   PubMed=16372000; DOI=10.1038/nature04341;
RA   Galagan J.E., Calvo S.E., Cuomo C., Ma L.J., Wortman J.R.,
RA   Batzoglou S., Lee S.I., Basturkmen M., Spevak C.C., Clutterbuck J.,
RA   Kapitonov V., Jurka J., Scazzocchio C., Farman M., Butler J.,
RA   Purcell S., Harris S., Braus G.H., Draht O., Busch S., D'Enfert C.,
RA   Bouchier C., Goldman G.H., Bell-Pedersen D., Griffiths-Jones S.,
RA   Doonan J.H., Yu J., Vienken K., Pain A., Freitag M., Selker E.U.,
RA   Archer D.B., Penalva M.A., Oakley B.R., Momany M., Tanaka T.,
RA   Kumagai T., Asai K., Machida M., Nierman W.C., Denning D.W.,
RA   Caddick M., Hynes M., Paoletti M., Fischer R., Miller B., Dyer P.,
RA   Sachs M.S., Osmani S.A., Birren B.W.;
RT   "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT   fumigatus and A. oryzae.";
RL   Nature 438:1105-1115(2005).
RN   [2] {ECO:0000313|Proteomes:UP000000560}
RP   GENOME REANNOTATION.
RC   STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139
RC   {ECO:0000313|Proteomes:UP000000560};
RX   PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA   Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA   Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P.,
RA   von Dohren H., Doonan J., Driessen A.J., Durek P., Espeso E.,
RA   Fekete E., Flipphi M., Estrada C.G., Geysens S., Goldman G.,
RA   de Groot P.W., Hansen K., Harris S.D., Heinekamp T., Helmstaedt K.,
RA   Henrissat B., Hofmann G., Homan T., Horio T., Horiuchi H., James S.,
RA   Jones M., Karaffa L., Karanyi Z., Kato M., Keller N., Kelly D.E.,
RA   Kiel J.A., Kim J.M., van der Klei I.J., Klis F.M., Kovalchuk A.,
RA   Krasevec N., Kubicek C.P., Liu B., Maccabe A., Meyer V., Mirabito P.,
RA   Miskei M., Mos M., Mullins J., Nelson D.R., Nielsen J., Oakley B.R.,
RA   Osmani S.A., Pakula T., Paszewski A., Paulsen I., Pilsyk S., Pocsi I.,
RA   Punt P.J., Ram A.F., Ren Q., Robellet X., Robson G., Seiboth B.,
RA   van Solingen P., Specht T., Sun J., Taheri-Talesh N., Takeshita N.,
RA   Ussery D., vanKuyk P.A., Visser H., van de Vondervoort P.J.,
RA   de Vries R.P., Walton J., Xiang X., Xiong Y., Zeng A.P., Brandt B.W.,
RA   Cornell M.J., van den Hondel C.A., Visser J., Oliver S.G., Turner G.;
RT   "The 2008 update of the Aspergillus nidulans genome annotation: a
RT   community effort.";
RL   Fungal Genet. Biol. 46:S2-13(2009).
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DR   EMBL; BN001307; CBF85042.1; -; Genomic_DNA.
DR   RefSeq; XP_659128.1; XM_654036.1.
DR   STRING; 162425.CADANIAP00008152; -.
DR   EnsemblFungi; CADANIAT00008152; CADANIAP00008152; CADANIAG00008152.
DR   EnsemblFungi; EAA63780; EAA63780; AN1524.2.
DR   GeneID; 2875245; -.
DR   KEGG; ani:AN1524.2; -.
DR   HOGENOM; HOG000158212; -.
DR   KO; K00295; -.
DR   OMA; YHNVRFL; -.
DR   OrthoDB; EOG092C3E8S; -.
DR   Proteomes; UP000000560; Chromosome VII.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0004487; F:methylenetetrahydrofolate dehydrogenase (NAD+) activity; IBA:GO_Central.
DR   GO; GO:0006730; P:one-carbon metabolic process; IBA:GO_Central.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   InterPro; IPR000672; THF_DH/CycHdrlase.
DR   InterPro; IPR020630; THF_DH/CycHdrlase_cat_dom.
DR   InterPro; IPR020631; THF_DH/CycHdrlase_NAD-bd_dom.
DR   PANTHER; PTHR10025; PTHR10025; 1.
DR   Pfam; PF00763; THF_DHG_CYH; 1.
DR   Pfam; PF02882; THF_DHG_CYH_C; 1.
DR   PRINTS; PR00085; THFDHDRGNASE.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   4: Predicted;
DR   PRODOM; Q5BD56.
DR   SWISS-2DPAGE; Q5BD56.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000560};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000560}.
SQ   SEQUENCE   334 AA;  37184 MW;  867E46E5A68C33F6 CRC64;
     MATPSEPAPT NCKVMLSKHV ANGLLAEVSE GIKTLEKPPH LVGFLANNDP AALMYAQWTE
     KTCHENGFRY SLREVHRDNL EEAILAANVD PDVDGIIVYY PIFNNRQDQY LQQIVDVSKD
     VEGLSHRYIF NMYQNIRFLD PETKRQKCIL PCTPLAIVKI LEHLNIYNTV LPYGNRLHGH
     TICVVNRSEV VGRPLAALLA NDGACVYSVD ITGIQKFYRG TGLKLGRHEV EDVEGKELKD
     IVPLCDTVIS GVPGDKYKFD TSLLRDGAVC INFSSEKNFG PEVKQKASIF VPSIGKVTIV
     VLLRNLLRLI QNKRMDDIKP AAATERPGTL EAAS
//

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