SWISSPROT: D3UY20_XENBS

ID   D3UY20_XENBS            Unreviewed;       460 AA.
AC   D3UY20;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   08-MAY-2019, entry version 49.
DE   SubName: Full=Putative transport protein (MFS family) {ECO:0000313|EMBL:CBJ79198.1};
GN   Name=hsrA {ECO:0000313|EMBL:CBJ79198.1};
GN   OrderedLocusNames=XBJ1_0043 {ECO:0000313|EMBL:CBJ79198.1};
OS   Xenorhabdus bovienii (strain SS-2004).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Xenorhabdus.
OX   NCBI_TaxID=406818 {ECO:0000313|EMBL:CBJ79198.1, ECO:0000313|Proteomes:UP000002045};
RN   [1] {ECO:0000313|Proteomes:UP000002045}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SS-2004 {ECO:0000313|Proteomes:UP000002045};
RA   Goodrich-Blair H., Barbazuk B., Bode H.B., Darby C., Du Z., Forst S.,
RA   Gaudriault S., Goldman B.S., Goodner B., Henkhaus J., Latreille P.,
RA   Medigue C., Miller N., Norton S., Ogier J.C., Rouy Z., Slater S.,
RA   Suen G.;
RT   "Complete genome sequence of Xenorhabdus nematophila (strain ATCC
RT   19061 / DSM 3370 / LMG 1036 / NCIB 9965 / AN6).";
RL   Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CBJ79198.1, ECO:0000313|Proteomes:UP000002045}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SS-2004 {ECO:0000313|EMBL:CBJ79198.1,
RC   ECO:0000313|Proteomes:UP000002045};
RX   PubMed=22125637; DOI=10.1371/journal.pone.0027909;
RA   Chaston J.M., Suen G., Tucker S.L., Andersen A.W., Bhasin A., Bode E.,
RA   Bode H.B., Brachmann A.O., Cowles C.E., Cowles K.N., Darby C.,
RA   de Leon L., Drace K., Du Z., Givaudan A., Herbert Tran E.E.,
RA   Jewell K.A., Knack J.J., Krasomil-Osterfeld K.C., Kukor R., Lanois A.,
RA   Latreille P., Leimgruber N.K., Lipke C.M., Liu R., Lu X.,
RA   Martens E.C., Marri P.R., Medigue C., Menard M.L., Miller N.M.,
RA   Morales-Soto N., Norton S., Ogier J.C., Orchard S.S., Park D.,
RA   Park Y., Qurollo B.A., Sugar D.R., Richards G.R., Rouy Z.,
RA   Slominski B., Slominski K., Snyder H., Tjaden B.C., van der Hoeven R.,
RA   Welch R.D., Wheeler C., Xiang B., Barbazuk B., Gaudriault S.,
RA   Goodner B., Slater S.C., Forst S., Goldman B.S., Goodrich-Blair H.;
RT   "The entomopathogenic bacterial endosymbionts xenorhabdus and
RT   photorhabdus: convergent lifestyles from divergent genomes.";
RL   PLoS ONE 6:e27909-e27909(2011).
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000256|SAAS:SAAS00769108}.
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DR   EMBL; FN667741; CBJ79198.1; -; Genomic_DNA.
DR   RefSeq; WP_012986671.1; NC_013892.1.
DR   STRING; 406818.XBJ1_0043; -.
DR   EnsemblBacteria; CBJ79198; CBJ79198; XBJ1_0043.
DR   GeneID; 8829670; -.
DR   KEGG; xbo:XBJ1_0043; -.
DR   PATRIC; fig|406818.4.peg.39; -.
DR   eggNOG; ENOG4105C0R; Bacteria.
DR   eggNOG; ENOG410XNN3; LUCA.
DR   HOGENOM; HOG000193484; -.
DR   OMA; TALFMEN; -.
DR   BioCyc; XBOV406818:XBJ1_RS00195-MONOMER; -.
DR   Proteomes; UP000002045; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd06174; MFS; 1.
DR   InterPro; IPR004638; EmrB-like.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR001411; Tet-R_TetB/Drug-R_transptr.
DR   PANTHER; PTHR23501; PTHR23501; 1.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR00711; efflux_EmrB; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
DR   PRODOM; D3UY20.
DR   SWISS-2DPAGE; D3UY20.
KW   Cell membrane {ECO:0000256|SAAS:SAAS00769078};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002045};
KW   Membrane {ECO:0000256|SAAS:SAAS00769060, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002045};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00769091,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00769070,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00769034}.
FT   TRANSMEM     50     70       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     77     96       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    102    123       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    135    157       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    163    181       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    193    213       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    225    243       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    263    288       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    294    317       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    329    346       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    352    372       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    393    416       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    428    449       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       11    454       MFS. {ECO:0000259|PROSITE:PS50850}.
SQ   SEQUENCE   460 AA;  49912 MW;  57FCB62A10CA462E CRC64;
     MVKSARSMSG LPWIAAIAFF MQSLDATILN TALPAIAKSL NHHPLAMQPA IVSYTLTVAM
     LIPVSGWLAD RFGTQRIFIY AVSLFSLGSL ACALSSSFSF LVAARVIQGI GGAMMMPVAR
     LALLRAYPRS ELLPVLNFVT MPGLLGPILG PMLGGLLVTY ATWHWIFIIN IPIGLLGIIY
     AKKHMPNFTM PKCFFDFLGF MLFSVGLVML SVSFDLFGNN TLPNYVPVAV MAGSIIMLSG
     YIFHAKRHPN PLIDLQLFQT RTFSVGITSN IATRLSTGSL SFLIPLMLQV GFGYSAVIAG
     IMMAPNAIGA ILAKSFVTKL LTQFGYRNTL IWVTVIIGVM IAQFSLQTPE ISLVFLIIPL
     FVLGMAMSTQ FTSMNTITLG DLNNNNASAG NSLLAVTQQL SISLGVTVSA AILRFYESAE
     YGSTVDHFHY TFITIGVITL ASSFVFLLLK KEDGRNLIKK
//