(data stored in ACNUC1104 zone)

SWISSPROT: D3UWC5_XENBS

ID   D3UWC5_XENBS            Unreviewed;       424 AA.
AC   D3UWC5;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   08-MAY-2019, entry version 51.
DE   SubName: Full=Homocysteine synthase {ECO:0000313|EMBL:CBJ79634.1};
DE            EC=2.5.1.49 {ECO:0000313|EMBL:CBJ79634.1};
GN   Name=metY {ECO:0000313|EMBL:CBJ79634.1};
GN   OrderedLocusNames=XBJ1_0485 {ECO:0000313|EMBL:CBJ79634.1};
OS   Xenorhabdus bovienii (strain SS-2004).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Xenorhabdus.
OX   NCBI_TaxID=406818 {ECO:0000313|EMBL:CBJ79634.1, ECO:0000313|Proteomes:UP000002045};
RN   [1] {ECO:0000313|Proteomes:UP000002045}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SS-2004 {ECO:0000313|Proteomes:UP000002045};
RA   Goodrich-Blair H., Barbazuk B., Bode H.B., Darby C., Du Z., Forst S.,
RA   Gaudriault S., Goldman B.S., Goodner B., Henkhaus J., Latreille P.,
RA   Medigue C., Miller N., Norton S., Ogier J.C., Rouy Z., Slater S.,
RA   Suen G.;
RT   "Complete genome sequence of Xenorhabdus nematophila (strain ATCC
RT   19061 / DSM 3370 / LMG 1036 / NCIB 9965 / AN6).";
RL   Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CBJ79634.1, ECO:0000313|Proteomes:UP000002045}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SS-2004 {ECO:0000313|EMBL:CBJ79634.1,
RC   ECO:0000313|Proteomes:UP000002045};
RX   PubMed=22125637; DOI=10.1371/journal.pone.0027909;
RA   Chaston J.M., Suen G., Tucker S.L., Andersen A.W., Bhasin A., Bode E.,
RA   Bode H.B., Brachmann A.O., Cowles C.E., Cowles K.N., Darby C.,
RA   de Leon L., Drace K., Du Z., Givaudan A., Herbert Tran E.E.,
RA   Jewell K.A., Knack J.J., Krasomil-Osterfeld K.C., Kukor R., Lanois A.,
RA   Latreille P., Leimgruber N.K., Lipke C.M., Liu R., Lu X.,
RA   Martens E.C., Marri P.R., Medigue C., Menard M.L., Miller N.M.,
RA   Morales-Soto N., Norton S., Ogier J.C., Orchard S.S., Park D.,
RA   Park Y., Qurollo B.A., Sugar D.R., Richards G.R., Rouy Z.,
RA   Slominski B., Slominski K., Snyder H., Tjaden B.C., van der Hoeven R.,
RA   Welch R.D., Wheeler C., Xiang B., Barbazuk B., Gaudriault S.,
RA   Goodner B., Slater S.C., Forst S., Goldman B.S., Goodrich-Blair H.;
RT   "The entomopathogenic bacterial endosymbionts xenorhabdus and
RT   photorhabdus: convergent lifestyles from divergent genomes.";
RL   PLoS ONE 6:e27909-e27909(2011).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|RuleBase:RU362118};
CC   -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC       {ECO:0000256|RuleBase:RU362118}.
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DR   EMBL; FN667741; CBJ79634.1; -; Genomic_DNA.
DR   RefSeq; WP_012987090.1; NC_013892.1.
DR   STRING; 406818.XBJ1_0485; -.
DR   EnsemblBacteria; CBJ79634; CBJ79634; XBJ1_0485.
DR   GeneID; 8830108; -.
DR   KEGG; xbo:XBJ1_0485; -.
DR   PATRIC; fig|406818.4.peg.444; -.
DR   eggNOG; ENOG4108IQK; Bacteria.
DR   eggNOG; COG2873; LUCA.
DR   HOGENOM; HOG000246417; -.
DR   KO; K01740; -.
DR   OMA; NPRFNIP; -.
DR   BioCyc; XBOV406818:XBJ1_RS02095-MONOMER; -.
DR   Proteomes; UP000002045; Chromosome.
DR   GO; GO:0003961; F:O-acetylhomoserine aminocarboxypropyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   CDD; cd00614; CGS_like; 1.
DR   Gene3D; 3.40.640.10; -; 1.
DR   Gene3D; 3.90.1150.10; -; 1.
DR   InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR   InterPro; IPR006235; OAc-hSer/O-AcSer_sulfhydrylase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_dom1.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR   PIRSF; PIRSF001434; CGS; 1.
DR   SUPFAM; SSF53383; SSF53383; 1.
DR   TIGRFAMs; TIGR01326; OAH_OAS_sulfhy; 1.
DR   PROSITE; PS00868; CYS_MET_METAB_PP; 1.
PE   3: Inferred from homology;
DR   PRODOM; D3UWC5.
DR   SWISS-2DPAGE; D3UWC5.
KW   Complete proteome {ECO:0000313|Proteomes:UP000002045};
KW   Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR001434-2,
KW   ECO:0000256|RuleBase:RU362118};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002045};
KW   Transferase {ECO:0000313|EMBL:CBJ79634.1}.
FT   MOD_RES     204    204       N6-(pyridoxal phosphate)lysine.
FT                                {ECO:0000256|PIRSR:PIRSR001434-2}.
SQ   SEQUENCE   424 AA;  45752 MW;  189C1061856307DC CRC64;
     MKLETLSIHA GYSPDPATKA VAVPIYQTTS YAFDDTQHGA DLFDLKVEGN IYSRMMNPTN
     DVLEKRIAAL EGGIGALSVA SGMAAVTYAI QAIAQAGDNI ISVAKLYGGT YNVMAHTFPS
     IGIETRFVDH NDIAAIEALI DEKTKAVYCE SITNPGGHII DIQAMADVAH KYGIPLIVDN
     TVATPYLCRP FEHGADIVIH SLTKYIGGHG TTIGGIIVDS GKFPWAEHQD RFAILSTPDA
     SYHGIIYTEH FGAAAYIARC RVGPLRSTGA TLSAFSAFLI LQGLETLALR MERHTENTLK
     VAQYLNEHPQ VSWVKYAGLP EHPEHELAVR YMGGKPSSVL SFGIKGEEEA GTRFIDALEL
     IVRLVNIGDA KSLACHPAST THRQLNDAEM VKAGVSRDLI RLSIGIEHSD DIIADLSQAL
     DAAK
//

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