(data stored in ACNUC1104 zone)

SWISSPROT: D3UZ81_XENBS

ID   D3UZ81_XENBS            Unreviewed;       490 AA.
AC   D3UZ81;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   08-MAY-2019, entry version 59.
DE   RecName: Full=3-octaprenyl-4-hydroxybenzoate carboxy-lyase {ECO:0000256|HAMAP-Rule:MF_01636, ECO:0000256|SAAS:SAAS01052049};
DE            EC=4.1.1.98 {ECO:0000256|HAMAP-Rule:MF_01636};
DE   AltName: Full=Polyprenyl p-hydroxybenzoate decarboxylase {ECO:0000256|HAMAP-Rule:MF_01636};
GN   Name=ubiD {ECO:0000256|HAMAP-Rule:MF_01636,
GN   ECO:0000313|EMBL:CBJ79663.1};
GN   OrderedLocusNames=XBJ1_0514 {ECO:0000313|EMBL:CBJ79663.1};
OS   Xenorhabdus bovienii (strain SS-2004).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Xenorhabdus.
OX   NCBI_TaxID=406818 {ECO:0000313|EMBL:CBJ79663.1, ECO:0000313|Proteomes:UP000002045};
RN   [1] {ECO:0000313|EMBL:CBJ79663.1, ECO:0000313|Proteomes:UP000002045}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SS-2004 {ECO:0000313|EMBL:CBJ79663.1,
RC   ECO:0000313|Proteomes:UP000002045};
RX   PubMed=22125637; DOI=10.1371/journal.pone.0027909;
RA   Chaston J.M., Suen G., Tucker S.L., Andersen A.W., Bhasin A., Bode E.,
RA   Bode H.B., Brachmann A.O., Cowles C.E., Cowles K.N., Darby C.,
RA   de Leon L., Drace K., Du Z., Givaudan A., Herbert Tran E.E.,
RA   Jewell K.A., Knack J.J., Krasomil-Osterfeld K.C., Kukor R., Lanois A.,
RA   Latreille P., Leimgruber N.K., Lipke C.M., Liu R., Lu X.,
RA   Martens E.C., Marri P.R., Medigue C., Menard M.L., Miller N.M.,
RA   Morales-Soto N., Norton S., Ogier J.C., Orchard S.S., Park D.,
RA   Park Y., Qurollo B.A., Sugar D.R., Richards G.R., Rouy Z.,
RA   Slominski B., Slominski K., Snyder H., Tjaden B.C., van der Hoeven R.,
RA   Welch R.D., Wheeler C., Xiang B., Barbazuk B., Gaudriault S.,
RA   Goodner B., Slater S.C., Forst S., Goldman B.S., Goodrich-Blair H.;
RT   "The entomopathogenic bacterial endosymbionts xenorhabdus and
RT   photorhabdus: convergent lifestyles from divergent genomes.";
RL   PLoS ONE 6:e27909-e27909(2011).
CC   -!- FUNCTION: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy
CC       benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone
CC       biosynthesis. {ECO:0000256|HAMAP-Rule:MF_01636,
CC       ECO:0000256|SAAS:SAAS01052053}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 4-hydroxy-3-all-trans-polyprenylbenzoate + H(+) = a 2-
CC         all-trans-polyprenylphenol + CO2; Xref=Rhea:RHEA:41680,
CC         Rhea:RHEA-COMP:9514, Rhea:RHEA-COMP:9516, ChEBI:CHEBI:1269,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:78396;
CC         EC=4.1.1.98; Evidence={ECO:0000256|HAMAP-Rule:MF_01636,
CC         ECO:0000256|SAAS:SAAS01117958};
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_01636, ECO:0000256|SAAS:SAAS01052040};
CC   -!- COFACTOR:
CC       Name=prenyl-FMN; Xref=ChEBI:CHEBI:87746;
CC         Evidence={ECO:0000256|HAMAP-Rule:MF_01636};
CC       Note=Binds 1 prenylated FMN (prenyl-FMN) per subunit.
CC       {ECO:0000256|HAMAP-Rule:MF_01636};
CC   -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.
CC       {ECO:0000256|HAMAP-Rule:MF_01636, ECO:0000256|SAAS:SAAS01052055}.
CC   -!- SUBUNIT: Homohexamer. {ECO:0000256|HAMAP-Rule:MF_01636,
CC       ECO:0000256|SAAS:SAAS01052044}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-
CC       Rule:MF_01636, ECO:0000256|SAAS:SAAS01052038}; Peripheral membrane
CC       protein {ECO:0000256|HAMAP-Rule:MF_01636,
CC       ECO:0000256|SAAS:SAAS01052038}.
CC   -!- SIMILARITY: Belongs to the UbiD family. {ECO:0000256|HAMAP-
CC       Rule:MF_01636, ECO:0000256|SAAS:SAAS01057224}.
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DR   EMBL; FN667741; CBJ79663.1; -; Genomic_DNA.
DR   RefSeq; WP_012987119.1; NC_013892.1.
DR   STRING; 406818.XBJ1_0514; -.
DR   EnsemblBacteria; CBJ79663; CBJ79663; XBJ1_0514.
DR   GeneID; 8830137; -.
DR   KEGG; xbo:XBJ1_0514; -.
DR   PATRIC; fig|406818.4.peg.474; -.
DR   eggNOG; ENOG4105D3H; Bacteria.
DR   eggNOG; COG0043; LUCA.
DR   HOGENOM; HOG000227663; -.
DR   KO; K03182; -.
DR   OMA; IDATNKW; -.
DR   BioCyc; XBOV406818:XBJ1_RS02225-MONOMER; -.
DR   UniPathway; UPA00232; -.
DR   Proteomes; UP000002045; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008694; F:3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01636; UbiD; 1.
DR   InterPro; IPR002830; UbiD.
DR   InterPro; IPR023677; UbiD_bacteria.
DR   PANTHER; PTHR30108; PTHR30108; 1.
DR   Pfam; PF01977; UbiD; 1.
DR   TIGRFAMs; TIGR00148; TIGR00148; 1.
PE   3: Inferred from homology;
DR   PRODOM; D3UZ81.
DR   SWISS-2DPAGE; D3UZ81.
KW   Cell membrane {ECO:0000256|HAMAP-Rule:MF_01636,
KW   ECO:0000256|SAAS:SAAS01052047};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002045};
KW   Decarboxylase {ECO:0000256|HAMAP-Rule:MF_01636,
KW   ECO:0000256|SAAS:SAAS01052052};
KW   Flavoprotein {ECO:0000256|HAMAP-Rule:MF_01636,
KW   ECO:0000256|SAAS:SAAS01052043};
KW   FMN {ECO:0000256|HAMAP-Rule:MF_01636, ECO:0000256|SAAS:SAAS01052042};
KW   Lyase {ECO:0000256|HAMAP-Rule:MF_01636, ECO:0000256|SAAS:SAAS01052041,
KW   ECO:0000313|EMBL:CBJ79663.1};
KW   Manganese {ECO:0000256|HAMAP-Rule:MF_01636,
KW   ECO:0000256|SAAS:SAAS01052051};
KW   Membrane {ECO:0000256|HAMAP-Rule:MF_01636,
KW   ECO:0000256|SAAS:SAAS01052046};
KW   Metal-binding {ECO:0000256|HAMAP-Rule:MF_01636,
KW   ECO:0000256|SAAS:SAAS01052048};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002045};
KW   Ubiquinone biosynthesis {ECO:0000256|HAMAP-Rule:MF_01636,
KW   ECO:0000256|SAAS:SAAS01052050}.
FT   REGION      175    177       Prenyl-FMN binding. {ECO:0000256|HAMAP-
FT                                Rule:MF_01636}.
FT   REGION      189    191       Prenyl-FMN binding. {ECO:0000256|HAMAP-
FT                                Rule:MF_01636}.
FT   REGION      194    195       Prenyl-FMN binding. {ECO:0000256|HAMAP-
FT                                Rule:MF_01636}.
FT   ACT_SITE    287    287       Proton donor. {ECO:0000256|HAMAP-Rule:
FT                                MF_01636}.
FT   METAL       172    172       Manganese. {ECO:0000256|HAMAP-Rule:
FT                                MF_01636}.
FT   METAL       238    238       Manganese. {ECO:0000256|HAMAP-Rule:
FT                                MF_01636}.
SQ   SEQUENCE   490 AA;  55643 MW;  78022B4ED1C625FF CRC64;
     MKYRDLRDFL SLLEQSGELK RIRMEVDPYL EMTEIADRTL RAGGPALLFE NPKGYSMPVL
     CNLFGTPKRV AMGMGQDDVK ALHDVGKLLA FLKEPEPPKG FRDLVDKLPK FKQVLNMPTK
     RLNSAPCQEQ VWTGDEVDLT RIPVMHCWPE DAAPLITWGL TVTRGPNKER QNLGIYRQQV
     LGKNKLIMRW LSHRGGALDF QEWCQAHPGE RFPVSVALGA DPATILGAVT PIPDTLSEYA
     FAGLLRGHKT EVVKCLSNDL EVPASAEIIL EGYIEPDEMA PEGPYGDHTG YYNEVDMFPV
     FTITHITQRR DAIYHSTYTG RPPDEPAVLG VALNEVLVPI LQKQFPEIVD FYLPPEGCSY
     RLAVVTMKKQ YAGHAKRVMM GVWSYLRQFM YTKFIIVCDD DINARDWNDV IWAITTRMDP
     QRDTVLMENT PIDYLDFASP VSGLGSKMGL DATNKWPGET QREWGRPIVM SDEIRARVDE
     IWDKLEILKR
//

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