(data stored in ACNUC1104 zone)

SWISSPROT: D3UWG5_XENBS

ID   D3UWG5_XENBS            Unreviewed;       287 AA.
AC   D3UWG5;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   08-MAY-2019, entry version 51.
DE   RecName: Full=Phosphatidate cytidylyltransferase {ECO:0000256|RuleBase:RU003938};
DE            EC=2.7.7.41 {ECO:0000256|RuleBase:RU003938};
GN   Name=cdsA {ECO:0000313|EMBL:CBJ79739.1};
GN   OrderedLocusNames=XBJ1_0595 {ECO:0000313|EMBL:CBJ79739.1};
OS   Xenorhabdus bovienii (strain SS-2004).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Xenorhabdus.
OX   NCBI_TaxID=406818 {ECO:0000313|EMBL:CBJ79739.1, ECO:0000313|Proteomes:UP000002045};
RN   [1] {ECO:0000313|EMBL:CBJ79739.1, ECO:0000313|Proteomes:UP000002045}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SS-2004 {ECO:0000313|EMBL:CBJ79739.1,
RC   ECO:0000313|Proteomes:UP000002045};
RX   PubMed=22125637; DOI=10.1371/journal.pone.0027909;
RA   Chaston J.M., Suen G., Tucker S.L., Andersen A.W., Bhasin A., Bode E.,
RA   Bode H.B., Brachmann A.O., Cowles C.E., Cowles K.N., Darby C.,
RA   de Leon L., Drace K., Du Z., Givaudan A., Herbert Tran E.E.,
RA   Jewell K.A., Knack J.J., Krasomil-Osterfeld K.C., Kukor R., Lanois A.,
RA   Latreille P., Leimgruber N.K., Lipke C.M., Liu R., Lu X.,
RA   Martens E.C., Marri P.R., Medigue C., Menard M.L., Miller N.M.,
RA   Morales-Soto N., Norton S., Ogier J.C., Orchard S.S., Park D.,
RA   Park Y., Qurollo B.A., Sugar D.R., Richards G.R., Rouy Z.,
RA   Slominski B., Slominski K., Snyder H., Tjaden B.C., van der Hoeven R.,
RA   Welch R.D., Wheeler C., Xiang B., Barbazuk B., Gaudriault S.,
RA   Goodner B., Slater S.C., Forst S., Goldman B.S., Goodrich-Blair H.;
RT   "The entomopathogenic bacterial endosymbionts xenorhabdus and
RT   photorhabdus: convergent lifestyles from divergent genomes.";
RL   PLoS ONE 6:e27909-e27909(2011).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-
CC         1,2-diacyl-sn-glycerol + diphosphate; Xref=Rhea:RHEA:16229,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:33019, ChEBI:CHEBI:37563,
CC         ChEBI:CHEBI:58332, ChEBI:CHEBI:58608; EC=2.7.7.41;
CC         Evidence={ECO:0000256|RuleBase:RU003938};
CC   -!- PATHWAY: Phospholipid metabolism; CDP-diacylglycerol biosynthesis;
CC       CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.
CC       {ECO:0000256|RuleBase:RU003938}.
CC   -!- SIMILARITY: Belongs to the CDS family.
CC       {ECO:0000256|RuleBase:RU003938}.
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DR   EMBL; FN667741; CBJ79739.1; -; Genomic_DNA.
DR   RefSeq; WP_012987193.1; NC_013892.1.
DR   STRING; 406818.XBJ1_0595; -.
DR   EnsemblBacteria; CBJ79739; CBJ79739; XBJ1_0595.
DR   GeneID; 8830217; -.
DR   KEGG; xbo:XBJ1_0595; -.
DR   PATRIC; fig|406818.4.peg.548; -.
DR   eggNOG; ENOG4105KNE; Bacteria.
DR   eggNOG; COG0575; LUCA.
DR   HOGENOM; HOG000006168; -.
DR   KO; K00981; -.
DR   OMA; WEWGRLN; -.
DR   BioCyc; XBOV406818:XBJ1_RS02585-MONOMER; -.
DR   UniPathway; UPA00557; UER00614.
DR   Proteomes; UP000002045; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004605; F:phosphatidate cytidylyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016024; P:CDP-diacylglycerol biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR000374; PC_trans.
DR   PROSITE; PS01315; CDS; 1.
PE   3: Inferred from homology;
DR   PRODOM; D3UWG5.
DR   SWISS-2DPAGE; D3UWG5.
KW   Complete proteome {ECO:0000313|Proteomes:UP000002045};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU003938,
KW   ECO:0000313|EMBL:CBJ79739.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002045};
KW   Transferase {ECO:0000256|RuleBase:RU003938,
KW   ECO:0000313|EMBL:CBJ79739.1};
KW   Transmembrane {ECO:0000256|RuleBase:RU003938,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     28     44       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     56     73       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     85    106       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    118    138       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    150    171       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    192    208       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    220    237       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    267    285       Helical. {ECO:0000256|SAM:Phobius}.
SQ   SEQUENCE   287 AA;  31052 MW;  DABF2C4B2CD27FE0 CRC64;
     MLKYRLLTTL ILIPIVIAAL FLLPPSGFGL VVITVSVLAA WEWGQFAGLF TQAKRITLAV
     LFAVGLLALQ YSLSDFSHLI EKPQIVYLLW AGMIWWAAAI LLVTTYPASA SIWKSSTALR
     LLFGVLTIVP FYCGMMVLRT QGYENNTYHG AWWLLYAMLL VWGADSGAYV FGRTLGKHKM
     APRVSPGKTL EGLVGGVLTA ALISWLFGKF APVPVMPENL LLISAVVVIA SVFGDLTESM
     FKRESGIKDS SLLIPGHGGV MDRVDSLTAA VPVFAGLVLL ISSGFGL
//

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