(data stored in ACNUC1104 zone)

SWISSPROT: D3VG37_XENNA

ID   D3VG37_XENNA            Unreviewed;       618 AA.
AC   D3VG37;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   08-MAY-2019, entry version 57.
DE   RecName: Full=tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG {ECO:0000256|HAMAP-Rule:MF_00129, ECO:0000256|SAAS:SAAS01147114};
DE   AltName: Full=Glucose-inhibited division protein A {ECO:0000256|HAMAP-Rule:MF_00129};
GN   Name=mnmG {ECO:0000256|HAMAP-Rule:MF_00129};
GN   Synonyms=gidA {ECO:0000256|HAMAP-Rule:MF_00129,
GN   ECO:0000313|EMBL:CBJ88127.1};
GN   OrderedLocusNames=XNC1_0034 {ECO:0000313|EMBL:CBJ88127.1};
OS   Xenorhabdus nematophila (strain ATCC 19061 / DSM 3370 / LMG 1036 /
OS   NCIB 9965 / AN6).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Xenorhabdus.
OX   NCBI_TaxID=406817 {ECO:0000313|EMBL:CBJ88127.1, ECO:0000313|Proteomes:UP000008075};
RN   [1] {ECO:0000313|Proteomes:UP000008075}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19061 / DSM 3370 / LMG 1036 / NCIB 9965 / AN6
RC   {ECO:0000313|Proteomes:UP000008075};
RA   Goodrich-Blair H., Barbazuk B., Bode H.B., Darby C., Du Z., Forst S.,
RA   Gaudriault S., Goldman B.S., Goodner B., Henkhaus J., Latreille P.,
RA   Medigue C., Miller N., Norton S., Ogier J.C., Rouy Z., Slater S.,
RA   Suen G.;
RT   "Complete genome sequence of Xenorhabdus nematophila (strain ATCC
RT   19061 / DSM 3370 / LMG 1036 / NCIB 9965 / AN6).";
RL   Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CBJ88127.1, ECO:0000313|Proteomes:UP000008075}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19061 / DSM 3370 / LMG 1036 / NCIB 9965 / AN6
RC   {ECO:0000313|Proteomes:UP000008075};
RX   PubMed=22125637; DOI=10.1371/journal.pone.0027909;
RA   Chaston J.M., Suen G., Tucker S.L., Andersen A.W., Bhasin A., Bode E.,
RA   Bode H.B., Brachmann A.O., Cowles C.E., Cowles K.N., Darby C.,
RA   de Leon L., Drace K., Du Z., Givaudan A., Herbert Tran E.E.,
RA   Jewell K.A., Knack J.J., Krasomil-Osterfeld K.C., Kukor R., Lanois A.,
RA   Latreille P., Leimgruber N.K., Lipke C.M., Liu R., Lu X.,
RA   Martens E.C., Marri P.R., Medigue C., Menard M.L., Miller N.M.,
RA   Morales-Soto N., Norton S., Ogier J.C., Orchard S.S., Park D.,
RA   Park Y., Qurollo B.A., Sugar D.R., Richards G.R., Rouy Z.,
RA   Slominski B., Slominski K., Snyder H., Tjaden B.C., van der Hoeven R.,
RA   Welch R.D., Wheeler C., Xiang B., Barbazuk B., Gaudriault S.,
RA   Goodner B., Slater S.C., Forst S., Goldman B.S., Goodrich-Blair H.;
RT   "The entomopathogenic bacterial endosymbionts xenorhabdus and
RT   photorhabdus: convergent lifestyles from divergent genomes.";
RL   PLoS ONE 6:e27909-e27909(2011).
CC   -!- FUNCTION: NAD-binding protein involved in the addition of a
CC       carboxymethylaminomethyl (cmnm) group at the wobble position (U34)
CC       of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. {ECO:0000256|HAMAP-
CC       Rule:MF_00129, ECO:0000256|SAAS:SAAS01147112}.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_00129, ECO:0000256|SAAS:SAAS01080909};
CC   -!- SUBUNIT: Homodimer. Heterotetramer of two MnmE and two MnmG
CC       subunits. {ECO:0000256|HAMAP-Rule:MF_00129,
CC       ECO:0000256|SAAS:SAAS01147118}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00129,
CC       ECO:0000256|SAAS:SAAS01147113}.
CC   -!- SIMILARITY: Belongs to the MnmG family. {ECO:0000256|HAMAP-
CC       Rule:MF_00129, ECO:0000256|SAAS:SAAS01080916}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|HAMAP-Rule:MF_00129}.
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DR   EMBL; FN667742; CBJ88127.1; -; Genomic_DNA.
DR   STRING; 406817.XNC1_0034; -.
DR   EnsemblBacteria; CBJ88127; CBJ88127; XNC1_0034.
DR   KEGG; xne:XNC1_0034; -.
DR   eggNOG; ENOG4107RE5; Bacteria.
DR   eggNOG; COG0445; LUCA.
DR   HOGENOM; HOG000201059; -.
DR   KO; K03495; -.
DR   OMA; FRPGYAI; -.
DR   Proteomes; UP000008075; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0002098; P:tRNA wobble uridine modification; IEA:InterPro.
DR   Gene3D; 3.50.50.60; -; 2.
DR   HAMAP; MF_00129; MnmG_GidA; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR026904; GidA-assoc_3.
DR   InterPro; IPR004416; MnmG.
DR   InterPro; IPR002218; MnmG-rel.
DR   InterPro; IPR020595; MnmG-rel_CS.
DR   PANTHER; PTHR11806; PTHR11806; 1.
DR   PANTHER; PTHR11806:SF0; PTHR11806:SF0; 1.
DR   Pfam; PF13932; GIDA_assoc; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR00136; gidA; 1.
DR   PROSITE; PS01280; GIDA_1; 1.
DR   PROSITE; PS01281; GIDA_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; D3VG37.
DR   SWISS-2DPAGE; D3VG37.
KW   Complete proteome {ECO:0000313|Proteomes:UP000008075};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00129,
KW   ECO:0000256|SAAS:SAAS01147115};
KW   FAD {ECO:0000256|HAMAP-Rule:MF_00129, ECO:0000256|SAAS:SAAS01080904};
KW   Flavoprotein {ECO:0000256|HAMAP-Rule:MF_00129,
KW   ECO:0000256|SAAS:SAAS01080908};
KW   NAD {ECO:0000256|HAMAP-Rule:MF_00129, ECO:0000256|SAAS:SAAS01147117};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008075};
KW   tRNA processing {ECO:0000256|HAMAP-Rule:MF_00129,
KW   ECO:0000256|SAAS:SAAS01147111}.
FT   DOMAIN      402    616       GIDA_assoc. {ECO:0000259|Pfam:PF13932}.
FT   NP_BIND      13     18       FAD. {ECO:0000256|HAMAP-Rule:MF_00129}.
FT   NP_BIND     273    287       NAD. {ECO:0000256|HAMAP-Rule:MF_00129}.
SQ   SEQUENCE   618 AA;  68934 MW;  4AD97F9FCFDC19BE CRC64;
     MFYPEHFDVI IIGGGHAGTE AAMAAARMGR QTLLLTHNID TLGQMSCNPA IGGIGKGHLV
     KEIDALGGLM AKATDQAGIQ FRTLNASKGP AVRATRAQAD RVLYRQAVRT ALENQPNLMI
     FQQPVEDLIV ENNTVTGVVT RMSLKFKAKS VVLTVGTFLD GKIHIGLENY SGGRAGDPPA
     ISLSHRLREL PLRVARLKTG TPPRIDARSI DFSQLEQQLG DNPTPVFSFM GNAAQHPQQI
     LCYITHTNEK THEVIRSNLD RSPMYAGIIE GIGPRYCPSI EDKVMRFADR NAHQIFLEPE
     GLTSNEIYPN GISTSLPFDV QMQIVHSMKG MENARIIRPG YAIEYDFFDP RGLKQTLESK
     FIHGLFFAGQ INGTTGYEEA AAQGLLAGLN AARYATGEEG WFPRRDQAYI GVLVDDLCTL
     GTKEPYRMFT SRAEYRLMLR EDNADLRLTE QGRRLGLVDD LRWKHYSRKV EMIEQERQRL
     RNIWVHPHSD NLGDINQMLK TPLSKEANGE DLLRRPEMNY ELLTSLSRFA PGLTEAQAAD
     QVEIQVKYEG YIARQQEEIE KQLRNENTAL PVDLDYQQVS GLSNEVIAKL NDHKPSSIGQ
     ASRISGITPA AISILLVW
//

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