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ID D3VG37_XENNA Unreviewed; 618 AA.
AC D3VG37;
DT 20-APR-2010, integrated into UniProtKB/TrEMBL.
DT 20-APR-2010, sequence version 1.
DT 08-MAY-2019, entry version 57.
DE RecName: Full=tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG {ECO:0000256|HAMAP-Rule:MF_00129, ECO:0000256|SAAS:SAAS01147114};
DE AltName: Full=Glucose-inhibited division protein A {ECO:0000256|HAMAP-Rule:MF_00129};
GN Name=mnmG {ECO:0000256|HAMAP-Rule:MF_00129};
GN Synonyms=gidA {ECO:0000256|HAMAP-Rule:MF_00129,
GN ECO:0000313|EMBL:CBJ88127.1};
GN OrderedLocusNames=XNC1_0034 {ECO:0000313|EMBL:CBJ88127.1};
OS Xenorhabdus nematophila (strain ATCC 19061 / DSM 3370 / LMG 1036 /
OS NCIB 9965 / AN6).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Xenorhabdus.
OX NCBI_TaxID=406817 {ECO:0000313|EMBL:CBJ88127.1, ECO:0000313|Proteomes:UP000008075};
RN [1] {ECO:0000313|Proteomes:UP000008075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19061 / DSM 3370 / LMG 1036 / NCIB 9965 / AN6
RC {ECO:0000313|Proteomes:UP000008075};
RA Goodrich-Blair H., Barbazuk B., Bode H.B., Darby C., Du Z., Forst S.,
RA Gaudriault S., Goldman B.S., Goodner B., Henkhaus J., Latreille P.,
RA Medigue C., Miller N., Norton S., Ogier J.C., Rouy Z., Slater S.,
RA Suen G.;
RT "Complete genome sequence of Xenorhabdus nematophila (strain ATCC
RT 19061 / DSM 3370 / LMG 1036 / NCIB 9965 / AN6).";
RL Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBJ88127.1, ECO:0000313|Proteomes:UP000008075}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19061 / DSM 3370 / LMG 1036 / NCIB 9965 / AN6
RC {ECO:0000313|Proteomes:UP000008075};
RX PubMed=22125637; DOI=10.1371/journal.pone.0027909;
RA Chaston J.M., Suen G., Tucker S.L., Andersen A.W., Bhasin A., Bode E.,
RA Bode H.B., Brachmann A.O., Cowles C.E., Cowles K.N., Darby C.,
RA de Leon L., Drace K., Du Z., Givaudan A., Herbert Tran E.E.,
RA Jewell K.A., Knack J.J., Krasomil-Osterfeld K.C., Kukor R., Lanois A.,
RA Latreille P., Leimgruber N.K., Lipke C.M., Liu R., Lu X.,
RA Martens E.C., Marri P.R., Medigue C., Menard M.L., Miller N.M.,
RA Morales-Soto N., Norton S., Ogier J.C., Orchard S.S., Park D.,
RA Park Y., Qurollo B.A., Sugar D.R., Richards G.R., Rouy Z.,
RA Slominski B., Slominski K., Snyder H., Tjaden B.C., van der Hoeven R.,
RA Welch R.D., Wheeler C., Xiang B., Barbazuk B., Gaudriault S.,
RA Goodner B., Slater S.C., Forst S., Goldman B.S., Goodrich-Blair H.;
RT "The entomopathogenic bacterial endosymbionts xenorhabdus and
RT photorhabdus: convergent lifestyles from divergent genomes.";
RL PLoS ONE 6:e27909-e27909(2011).
CC -!- FUNCTION: NAD-binding protein involved in the addition of a
CC carboxymethylaminomethyl (cmnm) group at the wobble position (U34)
CC of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. {ECO:0000256|HAMAP-
CC Rule:MF_00129, ECO:0000256|SAAS:SAAS01147112}.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000256|HAMAP-
CC Rule:MF_00129, ECO:0000256|SAAS:SAAS01080909};
CC -!- SUBUNIT: Homodimer. Heterotetramer of two MnmE and two MnmG
CC subunits. {ECO:0000256|HAMAP-Rule:MF_00129,
CC ECO:0000256|SAAS:SAAS01147118}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00129,
CC ECO:0000256|SAAS:SAAS01147113}.
CC -!- SIMILARITY: Belongs to the MnmG family. {ECO:0000256|HAMAP-
CC Rule:MF_00129, ECO:0000256|SAAS:SAAS01080916}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC of feature annotation. {ECO:0000256|HAMAP-Rule:MF_00129}.
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DR EMBL; FN667742; CBJ88127.1; -; Genomic_DNA.
DR STRING; 406817.XNC1_0034; -.
DR EnsemblBacteria; CBJ88127; CBJ88127; XNC1_0034.
DR KEGG; xne:XNC1_0034; -.
DR eggNOG; ENOG4107RE5; Bacteria.
DR eggNOG; COG0445; LUCA.
DR HOGENOM; HOG000201059; -.
DR KO; K03495; -.
DR OMA; FRPGYAI; -.
DR Proteomes; UP000008075; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:UniProtKB-UniRule.
DR GO; GO:0002098; P:tRNA wobble uridine modification; IEA:InterPro.
DR Gene3D; 3.50.50.60; -; 2.
DR HAMAP; MF_00129; MnmG_GidA; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR026904; GidA-assoc_3.
DR InterPro; IPR004416; MnmG.
DR InterPro; IPR002218; MnmG-rel.
DR InterPro; IPR020595; MnmG-rel_CS.
DR PANTHER; PTHR11806; PTHR11806; 1.
DR PANTHER; PTHR11806:SF0; PTHR11806:SF0; 1.
DR Pfam; PF13932; GIDA_assoc; 1.
DR SUPFAM; SSF51905; SSF51905; 1.
DR TIGRFAMs; TIGR00136; gidA; 1.
DR PROSITE; PS01280; GIDA_1; 1.
DR PROSITE; PS01281; GIDA_2; 1.
PE 3: Inferred from homology;
DR PRODOM; D3VG37.
DR SWISS-2DPAGE; D3VG37.
KW Complete proteome {ECO:0000313|Proteomes:UP000008075};
KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00129,
KW ECO:0000256|SAAS:SAAS01147115};
KW FAD {ECO:0000256|HAMAP-Rule:MF_00129, ECO:0000256|SAAS:SAAS01080904};
KW Flavoprotein {ECO:0000256|HAMAP-Rule:MF_00129,
KW ECO:0000256|SAAS:SAAS01080908};
KW NAD {ECO:0000256|HAMAP-Rule:MF_00129, ECO:0000256|SAAS:SAAS01147117};
KW Reference proteome {ECO:0000313|Proteomes:UP000008075};
KW tRNA processing {ECO:0000256|HAMAP-Rule:MF_00129,
KW ECO:0000256|SAAS:SAAS01147111}.
FT DOMAIN 402 616 GIDA_assoc. {ECO:0000259|Pfam:PF13932}.
FT NP_BIND 13 18 FAD. {ECO:0000256|HAMAP-Rule:MF_00129}.
FT NP_BIND 273 287 NAD. {ECO:0000256|HAMAP-Rule:MF_00129}.
SQ SEQUENCE 618 AA; 68934 MW; 4AD97F9FCFDC19BE CRC64;
MFYPEHFDVI IIGGGHAGTE AAMAAARMGR QTLLLTHNID TLGQMSCNPA IGGIGKGHLV
KEIDALGGLM AKATDQAGIQ FRTLNASKGP AVRATRAQAD RVLYRQAVRT ALENQPNLMI
FQQPVEDLIV ENNTVTGVVT RMSLKFKAKS VVLTVGTFLD GKIHIGLENY SGGRAGDPPA
ISLSHRLREL PLRVARLKTG TPPRIDARSI DFSQLEQQLG DNPTPVFSFM GNAAQHPQQI
LCYITHTNEK THEVIRSNLD RSPMYAGIIE GIGPRYCPSI EDKVMRFADR NAHQIFLEPE
GLTSNEIYPN GISTSLPFDV QMQIVHSMKG MENARIIRPG YAIEYDFFDP RGLKQTLESK
FIHGLFFAGQ INGTTGYEEA AAQGLLAGLN AARYATGEEG WFPRRDQAYI GVLVDDLCTL
GTKEPYRMFT SRAEYRLMLR EDNADLRLTE QGRRLGLVDD LRWKHYSRKV EMIEQERQRL
RNIWVHPHSD NLGDINQMLK TPLSKEANGE DLLRRPEMNY ELLTSLSRFA PGLTEAQAAD
QVEIQVKYEG YIARQQEEIE KQLRNENTAL PVDLDYQQVS GLSNEVIAKL NDHKPSSIGQ
ASRISGITPA AISILLVW
//
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