(data stored in ACNUC1104 zone)

SWISSPROT: D3VG66_XENNA

ID   D3VG66_XENNA            Unreviewed;       836 AA.
AC   D3VG66;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   08-MAY-2019, entry version 49.
DE   SubName: Full=Bifunctional penicillin-binding protein 1a: transglycosylase (N-terminal) transpeptidase (C-terminal) {ECO:0000313|EMBL:CBJ88156.1};
DE            EC=2.4.2.- {ECO:0000313|EMBL:CBJ88156.1};
DE            EC=3.4.-.- {ECO:0000313|EMBL:CBJ88156.1};
GN   Name=mrcA {ECO:0000313|EMBL:CBJ88156.1};
GN   OrderedLocusNames=XNC1_0068 {ECO:0000313|EMBL:CBJ88156.1};
OS   Xenorhabdus nematophila (strain ATCC 19061 / DSM 3370 / LMG 1036 /
OS   NCIB 9965 / AN6).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Xenorhabdus.
OX   NCBI_TaxID=406817 {ECO:0000313|EMBL:CBJ88156.1, ECO:0000313|Proteomes:UP000008075};
RN   [1] {ECO:0000313|Proteomes:UP000008075}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19061 / DSM 3370 / LMG 1036 / NCIB 9965 / AN6
RC   {ECO:0000313|Proteomes:UP000008075};
RA   Goodrich-Blair H., Barbazuk B., Bode H.B., Darby C., Du Z., Forst S.,
RA   Gaudriault S., Goldman B.S., Goodner B., Henkhaus J., Latreille P.,
RA   Medigue C., Miller N., Norton S., Ogier J.C., Rouy Z., Slater S.,
RA   Suen G.;
RT   "Complete genome sequence of Xenorhabdus nematophila (strain ATCC
RT   19061 / DSM 3370 / LMG 1036 / NCIB 9965 / AN6).";
RL   Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CBJ88156.1, ECO:0000313|Proteomes:UP000008075}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19061 / DSM 3370 / LMG 1036 / NCIB 9965 / AN6
RC   {ECO:0000313|Proteomes:UP000008075};
RX   PubMed=22125637; DOI=10.1371/journal.pone.0027909;
RA   Chaston J.M., Suen G., Tucker S.L., Andersen A.W., Bhasin A., Bode E.,
RA   Bode H.B., Brachmann A.O., Cowles C.E., Cowles K.N., Darby C.,
RA   de Leon L., Drace K., Du Z., Givaudan A., Herbert Tran E.E.,
RA   Jewell K.A., Knack J.J., Krasomil-Osterfeld K.C., Kukor R., Lanois A.,
RA   Latreille P., Leimgruber N.K., Lipke C.M., Liu R., Lu X.,
RA   Martens E.C., Marri P.R., Medigue C., Menard M.L., Miller N.M.,
RA   Morales-Soto N., Norton S., Ogier J.C., Orchard S.S., Park D.,
RA   Park Y., Qurollo B.A., Sugar D.R., Richards G.R., Rouy Z.,
RA   Slominski B., Slominski K., Snyder H., Tjaden B.C., van der Hoeven R.,
RA   Welch R.D., Wheeler C., Xiang B., Barbazuk B., Gaudriault S.,
RA   Goodner B., Slater S.C., Forst S., Goldman B.S., Goodrich-Blair H.;
RT   "The entomopathogenic bacterial endosymbionts xenorhabdus and
RT   photorhabdus: convergent lifestyles from divergent genomes.";
RL   PLoS ONE 6:e27909-e27909(2011).
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DR   EMBL; FN667742; CBJ88156.1; -; Genomic_DNA.
DR   STRING; 406817.XNC1_0068; -.
DR   CAZy; GT51; Glycosyltransferase Family 51.
DR   EnsemblBacteria; CBJ88156; CBJ88156; XNC1_0068.
DR   KEGG; xne:XNC1_0068; -.
DR   eggNOG; ENOG4108JQC; Bacteria.
DR   eggNOG; COG5009; LUCA.
DR   HOGENOM; HOG000041138; -.
DR   KO; K05366; -.
DR   OMA; LAQMAMI; -.
DR   Proteomes; UP000008075; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   GO; GO:0016757; F:transferase activity, transferring glycosyl groups; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.3810.10; -; 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR001264; Glyco_trans_51.
DR   InterPro; IPR023346; Lysozyme-like_dom_sf.
DR   InterPro; IPR036950; PBP_transglycosylase.
DR   InterPro; IPR031376; PCB_OB.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   Pfam; PF17092; PCB_OB; 1.
DR   Pfam; PF00912; Transgly; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF53955; SSF53955; 1.
DR   SUPFAM; SSF56601; SSF56601; 1.
PE   4: Predicted;
DR   PRODOM; D3VG66.
DR   SWISS-2DPAGE; D3VG66.
KW   Complete proteome {ECO:0000313|Proteomes:UP000008075};
KW   Glycosyltransferase {ECO:0000313|EMBL:CBJ88156.1};
KW   Hydrolase {ECO:0000313|EMBL:CBJ88156.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008075};
KW   Transferase {ECO:0000256|SAAS:SAAS01077424,
KW   ECO:0000313|EMBL:CBJ88156.1}.
FT   DOMAIN       49    222       Transgly. {ECO:0000259|Pfam:PF00912}.
FT   DOMAIN      309    418       PCB_OB. {ECO:0000259|Pfam:PF17092}.
FT   DOMAIN      421    596       Transpeptidase. {ECO:0000259|Pfam:
FT                                PF00905}.
SQ   SEQUENCE   836 AA;  92181 MW;  4BB45C6BCB703E63 CRC64;
     MILIVVCILL GTASIFGLYK YIEPQLPDVA TLKDVRLQTP MQVFSADDEL IAQYGEKRRL
     PLTLSEMPPL MVKAFIATED SRFYEHHGVD PIGIIRAVSV VMTSGHATQG ASTITQQLAR
     NFFLSPEKTL IRKAKEAFLA IKIEQLLTKD EILELYLNKI YLGQRAYGIG AAAQVYFGKT
     VNELTLSEMA MIAGLPKAPS TFNPLYSYDR AMSRRNVVLG RMLEEGYITQ RQYNEAREEK
     LVARYHGPQI VFSAPYLTEM ARQEIINRYG ENAYTDGYKV YTTITRKAQL AAVNAVRTNV
     IDYDIRHGYR GAQEVLWKAS QPAWDQALII NKLKTLPKYG PLVPAVVTGS SANQAEAMLV
     DGSKVELTMA GVRWARSFKT DSLQGPVPRR VNDVIHAGEQ IWVRKVNDIW WLAQLPQVNA
     ALVSINPLNG AVEALVGGFN FELSKFNRVT QSLRQVGSNI KPFLYTAAMD KGLTLASLLN
     DAPISRWDAG AGTDWRPKNS PPTYDGPVRL RQGLGQSKNV VMVRAMRAMG VDYAADYLKR
     FGLPGENVVR TESLALGSPS FTPMQLVRGY AVMANGGYLV DPYFIARIEN EEGNVLFEAK
     PKLACPQCEN IPVIYGETAR SIELSEDSIE NVAHSDEPQD SALPPQPDLE RVSANTDVDD
     QQYAPHVIST PLAFLIHDAL NTNVFGEPGW MGTGWRAARD LKRRDIGGKT GTTNSSKDAW
     FSGYGPDIVA TAWIGFDEHS RSLGRTPALK GEGGAKTAQP IWDDFMKVAL EGVPEKIMEP
     PAGIVSVTID RATGKLSSGG GNTRKEYFIE GTQPTEYAVP DVGTTVTENG ESHELF
//

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