(data stored in ACNUC1104 zone)

SWISSPROT: D3VIL7_XENNA

ID   D3VIL7_XENNA            Unreviewed;       388 AA.
AC   D3VIL7;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   08-MAY-2019, entry version 55.
DE   RecName: Full=GTPase Obg {ECO:0000256|HAMAP-Rule:MF_01454};
DE            EC=3.6.5.- {ECO:0000256|HAMAP-Rule:MF_01454};
DE   AltName: Full=GTP-binding protein Obg {ECO:0000256|HAMAP-Rule:MF_01454};
GN   Name=obgE {ECO:0000313|EMBL:CBJ88567.1};
GN   Synonyms=obg {ECO:0000256|HAMAP-Rule:MF_01454};
GN   OrderedLocusNames=XNC1_0493 {ECO:0000313|EMBL:CBJ88567.1};
OS   Xenorhabdus nematophila (strain ATCC 19061 / DSM 3370 / LMG 1036 /
OS   NCIB 9965 / AN6).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Xenorhabdus.
OX   NCBI_TaxID=406817 {ECO:0000313|EMBL:CBJ88567.1, ECO:0000313|Proteomes:UP000008075};
RN   [1] {ECO:0000313|Proteomes:UP000008075}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19061 / DSM 3370 / LMG 1036 / NCIB 9965 / AN6
RC   {ECO:0000313|Proteomes:UP000008075};
RA   Goodrich-Blair H., Barbazuk B., Bode H.B., Darby C., Du Z., Forst S.,
RA   Gaudriault S., Goldman B.S., Goodner B., Henkhaus J., Latreille P.,
RA   Medigue C., Miller N., Norton S., Ogier J.C., Rouy Z., Slater S.,
RA   Suen G.;
RT   "Complete genome sequence of Xenorhabdus nematophila (strain ATCC
RT   19061 / DSM 3370 / LMG 1036 / NCIB 9965 / AN6).";
RL   Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CBJ88567.1, ECO:0000313|Proteomes:UP000008075}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19061 / DSM 3370 / LMG 1036 / NCIB 9965 / AN6
RC   {ECO:0000313|Proteomes:UP000008075};
RX   PubMed=22125637; DOI=10.1371/journal.pone.0027909;
RA   Chaston J.M., Suen G., Tucker S.L., Andersen A.W., Bhasin A., Bode E.,
RA   Bode H.B., Brachmann A.O., Cowles C.E., Cowles K.N., Darby C.,
RA   de Leon L., Drace K., Du Z., Givaudan A., Herbert Tran E.E.,
RA   Jewell K.A., Knack J.J., Krasomil-Osterfeld K.C., Kukor R., Lanois A.,
RA   Latreille P., Leimgruber N.K., Lipke C.M., Liu R., Lu X.,
RA   Martens E.C., Marri P.R., Medigue C., Menard M.L., Miller N.M.,
RA   Morales-Soto N., Norton S., Ogier J.C., Orchard S.S., Park D.,
RA   Park Y., Qurollo B.A., Sugar D.R., Richards G.R., Rouy Z.,
RA   Slominski B., Slominski K., Snyder H., Tjaden B.C., van der Hoeven R.,
RA   Welch R.D., Wheeler C., Xiang B., Barbazuk B., Gaudriault S.,
RA   Goodner B., Slater S.C., Forst S., Goldman B.S., Goodrich-Blair H.;
RT   "The entomopathogenic bacterial endosymbionts xenorhabdus and
RT   photorhabdus: convergent lifestyles from divergent genomes.";
RL   PLoS ONE 6:e27909-e27909(2011).
CC   -!- FUNCTION: An essential GTPase which binds GTP, GDP and possibly
CC       (p)ppGpp with moderate affinity, with high nucleotide exchange
CC       rates and a fairly low GTP hydrolysis rate. Plays a role in
CC       control of the cell cycle, stress response, ribosome biogenesis
CC       and in those bacteria that undergo differentiation, in
CC       morphogenesis control. {ECO:0000256|HAMAP-Rule:MF_01454}.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_01454};
CC   -!- SUBUNIT: Monomer. {ECO:0000256|HAMAP-Rule:MF_01454}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01454}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class OBG-HflX-like GTPase
CC       superfamily. OBG GTPase family. {ECO:0000256|HAMAP-Rule:MF_01454}.
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DR   EMBL; FN667742; CBJ88567.1; -; Genomic_DNA.
DR   RefSeq; WP_013183296.1; NC_014228.1.
DR   STRING; 406817.XNC1_0493; -.
DR   EnsemblBacteria; CBJ88567; CBJ88567; XNC1_0493.
DR   KEGG; xne:XNC1_0493; -.
DR   eggNOG; ENOG4105C9R; Bacteria.
DR   eggNOG; COG0536; LUCA.
DR   HOGENOM; HOG000019084; -.
DR   KO; K03979; -.
DR   OMA; WVRQTDF; -.
DR   Proteomes; UP000008075; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003924; F:GTPase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-UniRule.
DR   CDD; cd01898; Obg; 1.
DR   Gene3D; 2.70.210.12; -; 1.
DR   HAMAP; MF_01454; GTPase_Obg; 1.
DR   InterPro; IPR031167; G_OBG.
DR   InterPro; IPR035101; GTP-bd_Obg.
DR   InterPro; IPR014100; GTP-bd_Obg/CgtA.
DR   InterPro; IPR006074; GTP1-OBG_CS.
DR   InterPro; IPR006169; GTP1_OBG_dom.
DR   InterPro; IPR036726; GTP1_OBG_dom_sf.
DR   InterPro; IPR006073; GTP_binding_domain.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF01018; GTP1_OBG; 1.
DR   Pfam; PF01926; MMR_HSR1; 1.
DR   PIRSF; PIRSF002401; GTP_bd_Obg/CgtA; 1.
DR   PRINTS; PR00326; GTP1OBG.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF82051; SSF82051; 1.
DR   TIGRFAMs; TIGR02729; Obg_CgtA; 1.
DR   PROSITE; PS51710; G_OBG; 1.
DR   PROSITE; PS00905; GTP1_OBG; 1.
PE   3: Inferred from homology;
DR   PRODOM; D3VIL7.
DR   SWISS-2DPAGE; D3VIL7.
KW   Complete proteome {ECO:0000313|Proteomes:UP000008075};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01454};
KW   GTP-binding {ECO:0000256|HAMAP-Rule:MF_01454};
KW   Hydrolase {ECO:0000256|HAMAP-Rule:MF_01454,
KW   ECO:0000313|EMBL:CBJ88567.1};
KW   Magnesium {ECO:0000256|HAMAP-Rule:MF_01454};
KW   Metal-binding {ECO:0000256|HAMAP-Rule:MF_01454};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01454};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008075}.
FT   DOMAIN      160    333       OBG-type G. {ECO:0000259|PROSITE:
FT                                PS51710}.
FT   NP_BIND     166    173       GTP. {ECO:0000256|HAMAP-Rule:MF_01454}.
FT   NP_BIND     191    195       GTP. {ECO:0000256|HAMAP-Rule:MF_01454}.
FT   NP_BIND     213    216       GTP. {ECO:0000256|HAMAP-Rule:MF_01454}.
FT   NP_BIND     283    286       GTP. {ECO:0000256|HAMAP-Rule:MF_01454}.
FT   NP_BIND     314    316       GTP. {ECO:0000256|HAMAP-Rule:MF_01454}.
FT   METAL       173    173       Magnesium. {ECO:0000256|HAMAP-Rule:
FT                                MF_01454}.
FT   METAL       193    193       Magnesium. {ECO:0000256|HAMAP-Rule:
FT                                MF_01454}.
SQ   SEQUENCE   388 AA;  43696 MW;  D8E7DB8F1B43EB21 CRC64;
     MKFVDEARIL VVAGDGGNGC VSFRREKYIP KGGPDGGDGG DGGDVYLLAD ENLNTLIDYR
     FEKSFRAERG QNGQSRDCTG KRGQDITIKV PVGTRVRDIG TGEVLGDMLR HEQRFMVAKG
     GFHGLGNTRF KSSVNRAPRQ RTMGTPGESR ELMLELMLLA DVGMLGMPNA GKSTFIRAVS
     AAKPKVADYP FTTLVPSLGV VRMDNEQSFV VADIPGLIEG ASEGAGLGIR FLKHLERCRV
     LLHLIDLCPI DESNPVENAR IIIRELYKYS EKLAEKPRWL VFNKVDLIDS EEAKQRAKAI
     ADELGWEGDY YMISAVNRQG VKELCWDIME FMKTQPRSME MSEEAQPEKV EFMWDDYHKE
     QLEQSSEDDF DDDWDEDDDE GIEFIYKR
//

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