(data stored in ACNUC1104 zone)

SWISSPROT: D3VIN5_XENNA

ID   D3VIN5_XENNA            Unreviewed;       649 AA.
AC   D3VIN5;
DT   20-APR-2010, integrated into UniProtKB/TrEMBL.
DT   20-APR-2010, sequence version 1.
DT   16-JAN-2019, entry version 55.
DE   RecName: Full=ATP-dependent RNA helicase DeaD {ECO:0000256|HAMAP-Rule:MF_00964};
DE            EC=3.6.4.13 {ECO:0000256|HAMAP-Rule:MF_00964};
DE   AltName: Full=Cold-shock DEAD box protein A {ECO:0000256|HAMAP-Rule:MF_00964};
GN   Name=deaD {ECO:0000256|HAMAP-Rule:MF_00964,
GN   ECO:0000313|EMBL:CBJ88585.1};
GN   OrderedLocusNames=XNC1_0511 {ECO:0000313|EMBL:CBJ88585.1};
OS   Xenorhabdus nematophila (strain ATCC 19061 / DSM 3370 / LMG 1036 /
OS   NCIB 9965 / AN6).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Xenorhabdus.
OX   NCBI_TaxID=406817 {ECO:0000313|EMBL:CBJ88585.1, ECO:0000313|Proteomes:UP000008075};
RN   [1] {ECO:0000313|Proteomes:UP000008075}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19061 / DSM 3370 / LMG 1036 / NCIB 9965 / AN6
RC   {ECO:0000313|Proteomes:UP000008075};
RA   Goodrich-Blair H., Barbazuk B., Bode H.B., Darby C., Du Z., Forst S.,
RA   Gaudriault S., Goldman B.S., Goodner B., Henkhaus J., Latreille P.,
RA   Medigue C., Miller N., Norton S., Ogier J.C., Rouy Z., Slater S.,
RA   Suen G.;
RT   "Complete genome sequence of Xenorhabdus nematophila (strain ATCC
RT   19061 / DSM 3370 / LMG 1036 / NCIB 9965 / AN6).";
RL   Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CBJ88585.1, ECO:0000313|Proteomes:UP000008075}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19061 / DSM 3370 / LMG 1036 / NCIB 9965 / AN6
RC   {ECO:0000313|Proteomes:UP000008075};
RX   PubMed=22125637; DOI=10.1371/journal.pone.0027909;
RA   Chaston J.M., Suen G., Tucker S.L., Andersen A.W., Bhasin A., Bode E.,
RA   Bode H.B., Brachmann A.O., Cowles C.E., Cowles K.N., Darby C.,
RA   de Leon L., Drace K., Du Z., Givaudan A., Herbert Tran E.E.,
RA   Jewell K.A., Knack J.J., Krasomil-Osterfeld K.C., Kukor R., Lanois A.,
RA   Latreille P., Leimgruber N.K., Lipke C.M., Liu R., Lu X.,
RA   Martens E.C., Marri P.R., Medigue C., Menard M.L., Miller N.M.,
RA   Morales-Soto N., Norton S., Ogier J.C., Orchard S.S., Park D.,
RA   Park Y., Qurollo B.A., Sugar D.R., Richards G.R., Rouy Z.,
RA   Slominski B., Slominski K., Snyder H., Tjaden B.C., van der Hoeven R.,
RA   Welch R.D., Wheeler C., Xiang B., Barbazuk B., Gaudriault S.,
RA   Goodner B., Slater S.C., Forst S., Goldman B.S., Goodrich-Blair H.;
RT   "The entomopathogenic bacterial endosymbionts xenorhabdus and
RT   photorhabdus: convergent lifestyles from divergent genomes.";
RL   PLoS ONE 6:e27909-e27909(2011).
CC   -!- FUNCTION: DEAD-box RNA helicase involved in various cellular
CC       processes at low temperature, including ribosome biogenesis, mRNA
CC       degradation and translation initiation. {ECO:0000256|HAMAP-
CC       Rule:MF_00964}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC         Evidence={ECO:0000256|HAMAP-Rule:MF_00964};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00964}.
CC   -!- SIMILARITY: Belongs to the DEAD box helicase family. DeaD
CC       subfamily. {ECO:0000256|HAMAP-Rule:MF_00964}.
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DR   EMBL; FN667742; CBJ88585.1; -; Genomic_DNA.
DR   RefSeq; WP_013183302.1; NC_014228.1.
DR   STRING; 406817.XNC1_0511; -.
DR   EnsemblBacteria; CBJ88585; CBJ88585; XNC1_0511.
DR   KEGG; xne:XNC1_0511; -.
DR   eggNOG; ENOG4105C1J; Bacteria.
DR   eggNOG; COG0513; LUCA.
DR   HOGENOM; HOG000268810; -.
DR   KO; K05592; -.
DR   OMA; LPQGMPK; -.
DR   Proteomes; UP000008075; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004004; F:ATP-dependent RNA helicase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0070417; P:cellular response to cold; IEA:InterPro.
DR   GO; GO:0000027; P:ribosomal large subunit assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0006401; P:RNA catabolic process; IEA:UniProtKB-UniRule.
DR   CDD; cd00079; HELICc; 1.
DR   CDD; cd12499; RRM_EcCsdA_like; 1.
DR   Gene3D; 3.30.70.330; -; 1.
DR   HAMAP; MF_00964; DEAD_helicase_DeaD; 1.
DR   InterPro; IPR034415; CsdA_RRM.
DR   InterPro; IPR005580; DbpA/CsdA_RNA-bd_dom.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR028618; DEAD_helicase_DeaD.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000629; RNA-helicase_DEAD-box_CS.
DR   InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR   Pfam; PF03880; DbpA; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS00039; DEAD_ATP_HELICASE; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS51195; Q_MOTIF; 1.
PE   3: Inferred from homology;
DR   PRODOM; D3VIN5.
DR   SWISS-2DPAGE; D3VIN5.
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00964,
KW   ECO:0000256|RuleBase:RU000492};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008075};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00964};
KW   Helicase {ECO:0000256|HAMAP-Rule:MF_00964,
KW   ECO:0000256|RuleBase:RU000492, ECO:0000313|EMBL:CBJ88585.1};
KW   Hydrolase {ECO:0000256|HAMAP-Rule:MF_00964,
KW   ECO:0000256|RuleBase:RU000492};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00964,
KW   ECO:0000256|RuleBase:RU000492};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008075};
KW   RNA-binding {ECO:0000256|HAMAP-Rule:MF_00964};
KW   Stress response {ECO:0000256|HAMAP-Rule:MF_00964}.
FT   DOMAIN        7     35       Q_MOTIF. {ECO:0000259|PROSITE:PS51195}.
FT   DOMAIN       38    209       Helicase ATP-binding.
FT                                {ECO:0000259|PROSITE:PS51192}.
FT   DOMAIN      233    380       Helicase C-terminal.
FT                                {ECO:0000259|PROSITE:PS51194}.
FT   MOTIF         7     35       Q motif. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00552}.
SQ   SEQUENCE   649 AA;  72529 MW;  AE21FAB1F458931E CRC64;
     MTTETEISFA DLGLSAPILS ALGDMGYEKP SPIQQQCIPH LLNGRDVLGM AQTGSGKTAA
     FTLPLLHNIN AELKAPQILV LAPTRELAVQ VAEACSDFSK HMRSVNVVAL YGGQRYDVQL
     RALRQGPQIV VGTPGRLLDH LKRGTLDLSN LKGLVLDEAD EMLRMGFIED VENIMSQIPA
     EHQTALFSAT MPEAIRRITR RFMNDPQEVR IQSSVTNRPD ISQSYWSVYG VRKNEALVRF
     LEAEDFDAAI IFVRTKNATL EVAEALERNG YNSAALNGDM NQTLREQTLE RLKNGRLDIL
     IATDVAARGL DVERISLVVN YDIPMDAESY VHRIGRTGRA GRAGRALLFV ENRERRLLRN
     IERTMKLTIP EVELPDAELL GQRRLEKFAA NVQQQLESSD LDQYRALLAK LGTDEELEME
     TLAAALLKMA QGERPLILPP DPVRRPRREF NDRDDRRRNG NGFGDRDKSD RGDRGDRGDR
     PRRERRDVGD MELYRIEVGR DDGVEVRHIV GAIANEGDIS SRYIGNIKLF ATHSTIELPK
     GMPGELLSHF TRTRILNKPL NMQLMGDAQP FERRERRGGG RNGNGNGGNG PRRDRDNAGN
     GNNGGRRFNN ERRGGGERGS FRGRNNDNFS GGAPRRRQSN DNGNSTSNV
//

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