(data stored in ACNUC1104 zone)

SWISSPROT: D0L8G5_GORB4

ID   D0L8G5_GORB4            Unreviewed;       518 AA.
AC   D0L8G5;
DT   15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT   15-DEC-2009, sequence version 1.
DT   08-MAY-2019, entry version 50.
DE   SubName: Full=Drug resistance transporter, EmrB/QacA subfamily {ECO:0000313|EMBL:ACY23913.1};
GN   OrderedLocusNames=Gbro_4798 {ECO:0000313|EMBL:ACY23913.1};
OS   Gordonia bronchialis (strain ATCC 25592 / DSM 43247 / JCM 3198 /
OS   NCTC 10667) (Rhodococcus bronchialis).
OC   Bacteria; Actinobacteria; Corynebacteriales; Gordoniaceae; Gordonia.
OX   NCBI_TaxID=526226 {ECO:0000313|EMBL:ACY23913.1, ECO:0000313|Proteomes:UP000001219};
RN   [1] {ECO:0000313|Proteomes:UP000001219}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25592 / DSM 43247 / JCM 3198 / NCTC 10667
RC   {ECO:0000313|Proteomes:UP000001219};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K.,
RA   Ivanova N., Ovchinnikova G., Saunders E., Brettin T., Detter J.C.,
RA   Han C., Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA   Hugenholtz P., Woyke T., Wu D., Jando M., Schneider S., Goeker M.,
RA   Klenk H.-P., Eisen J.A.;
RT   "The complete chromosome of Gordonia bronchialis DSM 43247.";
RL   Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ACY23913.1, ECO:0000313|Proteomes:UP000001219}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25592 / DSM 43247 / JCM 3198 / NCTC 10667
RC   {ECO:0000313|Proteomes:UP000001219};
RX   PubMed=21304674;
RA   Ivanova N., Sikorski J., Jando M., Lapidus A., Nolan M., Lucas S.,
RA   Del Rio T.G., Tice H., Copeland A., Cheng J.F., Chen F., Bruce D.,
RA   Goodwin L., Pitluck S., Mavromatis K., Ovchinnikova G., Pati A.,
RA   Chen A., Palaniappan K., Land M., Hauser L., Chang Y.J.,
RA   Jeffries C.D., Chain P., Saunders E., Han C., Detter J.C., Brettin T.,
RA   Rohde M., Goker M., Bristow J., Eisen J.A., Markowitz V.,
RA   Hugenholtz P., Klenk H.P., Kyrpides N.C.;
RT   "Complete genome sequence of Gordonia bronchialis type strain
RT   (3410).";
RL   Stand. Genomic Sci. 2:19-28(2010).
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000256|SAAS:SAAS00769108}.
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DR   EMBL; CP001802; ACY23913.1; -; Genomic_DNA.
DR   EnsemblBacteria; ACY23913; ACY23913; Gbro_4798.
DR   KEGG; gbr:Gbro_4798; -.
DR   eggNOG; ENOG4108J2T; Bacteria.
DR   eggNOG; ENOG4110BF6; LUCA.
DR   HOGENOM; HOG000239124; -.
DR   OMA; YVELRIA; -.
DR   Proteomes; UP000001219; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd06174; MFS; 1.
DR   InterPro; IPR004638; EmrB-like.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR00711; efflux_EmrB; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
DR   PRODOM; D0L8G5.
DR   SWISS-2DPAGE; D0L8G5.
KW   Cell membrane {ECO:0000256|SAAS:SAAS00769078};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001219};
KW   Membrane {ECO:0000256|SAAS:SAAS00769060, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001219};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00769091,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00769070,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00769034}.
FT   TRANSMEM     29     48       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     55     77       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     89    107       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    119    136       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    148    167       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    179    198       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    204    227       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    247    271       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    283    302       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    314    331       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    337    355       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        1    428       MFS. {ECO:0000259|PROSITE:PS50850}.
SQ   SEQUENCE   518 AA;  54567 MW;  11C0EB6EA6F866ED CRC64;
     MIMLDQTVVT VALPSMTHDL GLSSSGQQWV VNAYVLAMAA CVALGGKLGD RLGPVTCFCL
     GVVTFFAASV FCGLAPGGGG ETWILSARAA QGVGAALMMP VSAKIVMEAF PITERGRAMA
     VYAGVSQIFL AVGPLIGGAL TEWISWRAVF WLNVPVGLLA LVLVAIAKPD NSRDRAARVS
     LRGAAMLVTG LLLTVLAIQQ GSTWHWTAPA TLASLIVGVL ILGVFVLTQW RSATPLVAVR
     LLARRAFTAN LVTLGLVRFS LLATILFATL YLQDLLHMSP MKAGAAVLPL ILPITVAAQL
     GGRWYDRRGN RPPVITGLAI ATIGMACWSV ALPHLDYVLQ VPGMIITGFG LGLVFSPTNT
     DALSRVSAAE RSQASGLVQT IRQLGGTLGV AVIGSIVLGV EHQVTRTPIP QHGATRSRSA
     SGWRPPSSVW RSHAPSCCSR RSGSPCPAMS RRSPRCDGVR RSGHGTARPW DRHGRAGFWK
     GAVAQYSSAP MSAASASTWW LCALRPPTKD TATTATTQ
//

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