(data stored in ACNUC9543 zone)

SWISSPROT: D0MWF7_PHYIT

ID   D0MWF7_PHYIT            Unreviewed;      1158 AA.
AC   D0MWF7;
DT   15-DEC-2009, integrated into UniProtKB/TrEMBL.
DT   15-DEC-2009, sequence version 1.
DT   08-MAY-2019, entry version 59.
DE   SubName: Full=ATP-dependent RNA helicase DHX8 {ECO:0000313|EMBL:EEY63970.1};
GN   ORFNames=PITG_02482 {ECO:0000313|EMBL:EEY63970.1};
OS   Phytophthora infestans (strain T30-4) (Potato late blight fungus).
OC   Eukaryota; Stramenopiles; Oomycetes; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=403677 {ECO:0000313|Proteomes:UP000006643};
RN   [1] {ECO:0000313|Proteomes:UP000006643}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=T30-4 {ECO:0000313|Proteomes:UP000006643};
RX   PubMed=19741609; DOI=10.1038/nature08358;
RG   The Broad Institute Genome Sequencing Platform;
RA   Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E.,
RA   Cano L.M., Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T.,
RA   Bozkurt T.O., Ah-Fong A.M., Alvarado L., Anderson V.L.,
RA   Armstrong M.R., Avrova A., Baxter L., Beynon J., Boevink P.C.,
RA   Bollmann S.R., Bos J.I., Bulone V., Cai G., Cakir C., Carrington J.C.,
RA   Chawner M., Conti L., Costanzo S., Ewan R., Fahlgren N.,
RA   Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S., Green P.J.,
RA   Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K.,
RA   Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D.,
RA   Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L.,
RA   Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J.,
RA   Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M.,
RA   Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S.,
RA   Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D.,
RA   Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J.,
RA   Studholme D.J., Sykes S., Thines M., van de Vondervoort P.J.,
RA   Phuntumart V., Wawra S., Weide R., Win J., Young C., Zhou S., Fry W.,
RA   Meyers B.C., van West P., Ristaino J., Govers F., Birch P.R.,
RA   Whisson S.C., Judelson H.S., Nusbaum C.;
RT   "Genome sequence and analysis of the Irish potato famine pathogen
RT   Phytophthora infestans.";
RL   Nature 461:393-398(2009).
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DR   EMBL; DS028120; EEY63970.1; -; Genomic_DNA.
DR   RefSeq; XP_002907406.1; XM_002907360.1.
DR   STRING; 4787.PITG_02482T0; -.
DR   PRIDE; D0MWF7; -.
DR   EnsemblProtists; PITG_02482T0; PITG_02482T0; PITG_02482.
DR   GeneID; 9469929; -.
DR   KEGG; pif:PITG_02482; -.
DR   EuPathDB; FungiDB:PITG_02482; -.
DR   HOGENOM; HOG000175261; -.
DR   InParanoid; D0MWF7; -.
DR   KO; K12818; -.
DR   OMA; RIQKAIC; -.
DR   OrthoDB; 354219at2759; -.
DR   Proteomes; UP000006643; Partially assembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd00079; HELICc; 1.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR   InterPro; IPR011709; DUF1605.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR022967; S1_dom.
DR   InterPro; IPR003029; S1_domain.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF04408; HA2; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   Pfam; PF00575; S1; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SMART; SM00316; S1; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS50126; S1; 1.
PE   4: Predicted;
DR   PRODOM; D0MWF7.
DR   SWISS-2DPAGE; D0MWF7.
KW   ATP-binding {ECO:0000256|SAAS:SAAS01176619};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006643};
KW   Helicase {ECO:0000313|EMBL:EEY63970.1};
KW   Hydrolase {ECO:0000256|SAAS:SAAS01176622};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS01176608};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006643}.
FT   DOMAIN      201    272       S1 motif. {ECO:0000259|PROSITE:PS50126}.
FT   DOMAIN      513    676       Helicase ATP-binding.
FT                                {ECO:0000259|PROSITE:PS51192}.
FT   DOMAIN      702    876       Helicase C-terminal.
FT                                {ECO:0000259|PROSITE:PS51194}.
FT   COILED      413    433       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1158 AA;  131265 MW;  38E5BF13C3101980 CRC64;
     MEKLQELSLV SKVCQALENH LGMSDKTLAE FVIDLVRSSS SCTAFLASIK KDELPLPPAL
     AENLYRIVQT MAPRKMKQVG GSAADAKRKS KRHQIRDDEQ LTAADIAGAS VKDDKDDKKP
     TSTERDDRKS DDRSRTRDRS RDRDRYGRDR SRGRDEDRGR RGRRSRSRSR SEGRRRDRRD
     RDRDRSRGRR RDDPPRELEL YGIYDGRVAK VMDFGVFVEL EGFSREKKEG LVHVSNLSAN
     RVSNVKEFAK RGDRVKVKLI SISGAKLSMS MRDVDQRTGK DLMPQRSSDG AERARQENRS
     SDSRSWINPS APGMQSSQQL DEDDSKPQRA AKRMSSPERW EVQQLINSGV LSVEDYPTFD
     EEHGMLNTEA TEEDFEVELN EDEPVFLRGQ TQMSREISPV KIVKNPDGSM QRAAMTQSNL
     AKERRELRQT QANQLIDSIP KDLNRPWEDP MPDAGERHFA QELRGINMGS TFELPEWKQK
     SVGKNLSYGI VSNKTILEQR ESLPVFKLKR QLMKAIADNQ VLVVIGETGS GKTTQMTQYM
     AEMGLTSTGI IGCTQPRRVA ASSVAKRVAE EFGCELGQEV GYSMRFEDVT SPETVIKYMT
     EGMLLREYLA DSTLSKYSAL MLDEAHERTI NTDVLFGLLK DLVRTRKDLK IIVTSATLDA
     EKFSRYFFDC PIFTIPGRTF PVEILYTKEP ELDYLDACLL CVMQIHLSEP EGDILLFLTG
     QEEIDTACEV LYQRIKALQE RALAPELIIL PVYGALPSEM QSRIFEPAPK GSRKCVVATN
     IAEASLTIDG IYYVVDPGFC KQNAFNSKIG MDSLVVVPCS QASARQRAGR AGRTGPGKCY
     RLYTENAYKN EMLPTTVPEI QRANLGSVVL QLKAMGINDL MGFDFMDPPP QDALVMALEN
     LYALGALDDE GLLTRLGKKM AEFPVEPKNA KVLLTSVVLG CAEEVLTIVA MLSVESVFFR
     PKEKQAQADQ KKAKFHQPEG DHLTLLGVYE AWANSKFSNP WCYDNFIQAR AIRRAQDVRK
     QLLSILDRYK MDVVSCGKNY NKVRRAIVAG YFANTAKKDP QEGYRTMVEG QPVYIHPSSA
     LFNKSPEWVL YHELVLTTKE YMRNIMTIEP KWLVELAPAF FKKGDPTKLS KRKRNEKIEP
     LFDRFNPPDS WRLSKRRG
//

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