(data stored in SCRATCH zone)

SWISSPROT: D1CEC9_THET1

ID   D1CEC9_THET1            Unreviewed;       394 AA.
AC   D1CEC9;
DT   19-JAN-2010, integrated into UniProtKB/TrEMBL.
DT   19-JAN-2010, sequence version 1.
DT   08-MAY-2019, entry version 54.
DE   SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:ACZ41285.1};
DE            EC=2.3.1.9 {ECO:0000313|EMBL:ACZ41285.1};
GN   OrderedLocusNames=Tter_0363 {ECO:0000313|EMBL:ACZ41285.1};
OS   Thermobaculum terrenum (strain ATCC BAA-798 / YNP1).
OC   Bacteria; Thermobaculum.
OX   NCBI_TaxID=525904 {ECO:0000313|EMBL:ACZ41285.1, ECO:0000313|Proteomes:UP000000323};
RN   [1] {ECO:0000313|EMBL:ACZ41285.1, ECO:0000313|Proteomes:UP000000323}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-798 / YNP1 {ECO:0000313|Proteomes:UP000000323};
RX   PubMed=21304745;
RA   Kiss H., Cleland D., Lapidus A., Lucas S., Del Rio T.G., Nolan M.,
RA   Tice H., Han C., Goodwin L., Pitluck S., Liolios K., Ivanova N.,
RA   Mavromatis K., Ovchinnikova G., Pati A., Chen A., Palaniappan K.,
RA   Land M., Hauser L., Chang Y.J., Jeffries C.D., Lu M., Brettin T.,
RA   Detter J.C., Goker M., Tindall B.J., Beck B., McDermott T.R.,
RA   Woyke T., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA   Kyrpides N.C., Klenk H.P., Cheng J.F.;
RT   "Complete genome sequence of 'Thermobaculum terrenum' type strain
RT   (YNP1).";
RL   Stand. Genomic Sci. 3:153-162(2010).
RN   [2] {ECO:0000313|Proteomes:UP000000323}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-798 / YNP1 {ECO:0000313|Proteomes:UP000000323};
RX   DOI=10.4056/sigs.1153107;
RA   Kiss H., Cleland D., Lapidus A., Lucas S., Glavina Del Rio T.,
RA   Nolan M., Tice H., Han C., Goodwin L., Pitluck S., Liolios K.,
RA   Ivanova N., Mavromatis K., Ovchinnikova G., Pati A., Chen A.,
RA   Palaniappan K., Land M., Hauser L., Chang Y., Jeffries C., Lu M.,
RA   Brettin T., Detter J., Goker M., Tindall B., Beck B., McDermott T.,
RA   Woyke T., Bristow J., Eisen J., Markowitz V., Hugenholtz P.,
RA   Kyrpides N., Klenk H., Cheng J.;
RT   "Complete genome sequence of Thermobaculum terrenum type strain
RT   (YNP1T).";
RL   Stand. Genomic Sci. 3:153-162(2010).
CC   -!- SIMILARITY: Belongs to the thiolase family.
CC       {ECO:0000256|RuleBase:RU003557}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP001825; ACZ41285.1; -; Genomic_DNA.
DR   RefSeq; WP_012874320.1; NC_013525.1.
DR   STRING; 525904.Tter_0363; -.
DR   EnsemblBacteria; ACZ41285; ACZ41285; Tter_0363.
DR   KEGG; ttr:Tter_0363; -.
DR   eggNOG; ENOG4105CHU; Bacteria.
DR   eggNOG; COG0183; LUCA.
DR   HOGENOM; HOG000012238; -.
DR   KO; K00626; -.
DR   OMA; WDVYNKF; -.
DR   OrthoDB; 1058688at2; -.
DR   BioCyc; TTER525904:G1GGS-368-MONOMER; -.
DR   Proteomes; UP000000323; Chromosome 1.
DR   GO; GO:0003985; F:acetyl-CoA C-acetyltransferase activity; IEA:UniProtKB-EC.
DR   CDD; cd00751; thiolase; 1.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR002155; Thiolase.
DR   InterPro; IPR016039; Thiolase-like.
DR   InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR   InterPro; IPR020610; Thiolase_AS.
DR   InterPro; IPR020617; Thiolase_C.
DR   InterPro; IPR020613; Thiolase_CS.
DR   InterPro; IPR020616; Thiolase_N.
DR   Pfam; PF02803; Thiolase_C; 1.
DR   Pfam; PF00108; Thiolase_N; 1.
DR   PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR   SUPFAM; SSF53901; SSF53901; 2.
DR   TIGRFAMs; TIGR01930; AcCoA-C-Actrans; 1.
DR   PROSITE; PS00098; THIOLASE_1; 1.
DR   PROSITE; PS00737; THIOLASE_2; 1.
DR   PROSITE; PS00099; THIOLASE_3; 1.
PE   3: Inferred from homology;
DR   PRODOM; D1CEC9.
DR   SWISS-2DPAGE; D1CEC9.
KW   Acyltransferase {ECO:0000256|RuleBase:RU003557,
KW   ECO:0000313|EMBL:ACZ41285.1};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000323};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000323};
KW   Transferase {ECO:0000256|RuleBase:RU003557,
KW   ECO:0000313|EMBL:ACZ41285.1}.
FT   DOMAIN        5    263       Thiolase_N. {ECO:0000259|Pfam:PF00108}.
FT   DOMAIN      271    391       Thiolase_C. {ECO:0000259|Pfam:PF02803}.
FT   ACT_SITE     88     88       Acyl-thioester intermediate.
FT                                {ECO:0000256|PIRSR:PIRSR000429-1}.
FT   ACT_SITE    349    349       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR000429-1}.
FT   ACT_SITE    379    379       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR000429-1}.
SQ   SEQUENCE   394 AA;  41252 MW;  D14CBBA93DD56BC4 CRC64;
     MSRTAILSAV RTPIGKLGGA LASLSAVDLG AIVIRSAIER AGIPPSEVQH VIMGNVIGAG
     LGMTPARQAA FRAGLGREVT ADTLNRVCGS GMRAIALADA LIRLGEHNIV VAGGMESMSN
     APYLIPKARW GYRMGNGELL DAMIHDGLWD PILHVHMGNH GSSVASKEGV TRQQQDEWAL
     RSHKRAIAAI DAGRFDDEII PVEVSSNKGD KSLVDQDEAP RRDTSMEALS RLKPVFDPNG
     TVTAGNAPGV NDGASALVLA SEDYVRAHGL RPLAFILAQG AAAWDPPYLA YTPAMAAQQA
     LCKVNMLIDD MDLIEINEAF ASVAIISIRK LNADPEKVNV NGGAIALGHP IGASGARIVT
     TLLHELHRRG GGYGLAAICS GTAQGDALVL QVEG
//

If you have problems or comments...

PBIL Back to PBIL home page