(data stored in SCRATCH zone)

SWISSPROT: D1YVA4_METPS

ID   D1YVA4_METPS            Unreviewed;       106 AA.
AC   D1YVA4;
DT   09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT   09-FEB-2010, sequence version 1.
DT   11-DEC-2019, entry version 40.
DE   RecName: Full=Ribonuclease P protein component 4 {ECO:0000256|HAMAP-Rule:MF_00757};
DE            Short=RNase P component 4 {ECO:0000256|HAMAP-Rule:MF_00757};
DE            EC=3.1.26.5 {ECO:0000256|HAMAP-Rule:MF_00757};
DE   AltName: Full=Rpp21 {ECO:0000256|HAMAP-Rule:MF_00757};
GN   Name=rnp4 {ECO:0000256|HAMAP-Rule:MF_00757,
GN   ECO:0000313|EMBL:BAI60376.1};
GN   OrderedLocusNames=MCP_0304 {ECO:0000313|EMBL:BAI60376.1};
OS   Methanocella paludicola (strain DSM 17711 / JCM 13418 / NBRC 101707 /
OS   SANAE).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanocellales; Methanocellaceae; Methanocella.
OX   NCBI_TaxID=304371 {ECO:0000313|EMBL:BAI60376.1, ECO:0000313|Proteomes:UP000001882};
RN   [1] {ECO:0000313|Proteomes:UP000001882}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17711 / JCM 13418 / NBRC 101707 / SANAE
RC   {ECO:0000313|Proteomes:UP000001882};
RX   PubMed=21829548; DOI=10.1371/journal.pone.0022898;
RA   Sakai S., Takaki Y., Shimamura S., Sekine M., Tajima T., Kosugi H.,
RA   Ichikawa N., Tasumi E., Hiraki A.T., Shimizu A., Kato Y., Nishiko R.,
RA   Mori K., Fujita N., Imachi H., Takai K.;
RT   "Genome sequence of a mesophilic hydrogenotrophic methanogen Methanocella
RT   paludicola, the first cultivated representative of the order
RT   Methanocellales.";
RL   PLoS ONE 6:E22898-E22898(2011).
CC   -!- FUNCTION: Part of ribonuclease P, a protein complex that generates
CC       mature tRNA molecules by cleaving their 5'-ends. {ECO:0000256|HAMAP-
CC       Rule:MF_00757}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Endonucleolytic cleavage of RNA, removing 5'-extranucleotides
CC         from tRNA precursor.; EC=3.1.26.5; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_00757};
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|HAMAP-Rule:MF_00757};
CC       Note=Binds 1 zinc ion per subunit. {ECO:0000256|HAMAP-Rule:MF_00757};
CC   -!- SUBUNIT: Consists of a catalytic RNA component and at least 4-5 protein
CC       subunits. {ECO:0000256|HAMAP-Rule:MF_00757}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00757}.
CC   -!- SIMILARITY: Belongs to the eukaryotic/archaeal RNase P protein
CC       component 4 family. {ECO:0000256|HAMAP-Rule:MF_00757}.
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DR   EMBL; AP011532; BAI60376.1; -; Genomic_DNA.
DR   STRING; 304371.MCP_0304; -.
DR   EnsemblBacteria; BAI60376; BAI60376; MCP_0304.
DR   KEGG; mpd:MCP_0304; -.
DR   eggNOG; arCOG04345; Archaea.
DR   eggNOG; COG2023; LUCA.
DR   HOGENOM; HOG000230709; -.
DR   KO; K03540; -.
DR   OMA; HVVITCL; -.
DR   Proteomes; UP000001882; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0030677; C:ribonuclease P complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0004526; F:ribonuclease P activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0001682; P:tRNA 5'-leader removal; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00757; RNase_P_4; 1.
DR   InterPro; IPR016432; RNase_P_comp-4.
DR   InterPro; IPR007175; Rpr2.
DR   Pfam; PF04032; Rpr2; 1.
DR   PIRSF; PIRSF004878; RNase_P_4; 1.
PE   3: Inferred from homology;
DR   PRODOM; D1YVA4.
DR   SWISS-2DPAGE; D1YVA4.
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00757};
KW   Endonuclease {ECO:0000256|HAMAP-Rule:MF_00757};
KW   Hydrolase {ECO:0000256|HAMAP-Rule:MF_00757};
KW   Metal-binding {ECO:0000256|HAMAP-Rule:MF_00757};
KW   Nuclease {ECO:0000256|HAMAP-Rule:MF_00757};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001882};
KW   tRNA processing {ECO:0000256|HAMAP-Rule:MF_00757};
KW   Zinc {ECO:0000256|HAMAP-Rule:MF_00757}.
FT   METAL           68
FT                   /note="Zinc"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_00757"
FT   METAL           71
FT                   /note="Zinc"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_00757"
FT   METAL           94
FT                   /note="Zinc"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_00757"
FT   METAL           97
FT                   /note="Zinc"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_00757"
SQ   SEQUENCE   106 AA;  12476 MW;  8D30BD51EB5EC23A CRC64;
     MPERRRKEPQ RKPFNVDMAE QRIKRLFELA EQAYPGRPDL ADRYADIARR ISMRHRVGIP
     RELKRRVCKG CGSFLVPGDN CRVRLDGNNI VITCMKCGAI KRYPYR
//

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