(data stored in SCRATCH zone)

SWISSPROT: D1YVW8_METPS

ID   D1YVW8_METPS            Unreviewed;       161 AA.
AC   D1YVW8;
DT   09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT   09-FEB-2010, sequence version 1.
DT   11-DEC-2019, entry version 49.
DE   RecName: Full=Pyruvoyl-dependent arginine decarboxylase {ECO:0000256|HAMAP-Rule:MF_01404};
DE            Short=PvlArgDC {ECO:0000256|HAMAP-Rule:MF_01404};
DE            EC=4.1.1.19 {ECO:0000256|HAMAP-Rule:MF_01404};
DE   Contains:
DE     RecName: Full=Pyruvoyl-dependent arginine decarboxylase subunit beta {ECO:0000256|HAMAP-Rule:MF_01404};
DE   Contains:
DE     RecName: Full=Pyruvoyl-dependent arginine decarboxylase subunit alpha {ECO:0000256|HAMAP-Rule:MF_01404};
GN   Name=pdaD-1 {ECO:0000313|EMBL:BAI60590.1};
GN   Synonyms=pdaD {ECO:0000256|HAMAP-Rule:MF_01404};
GN   OrderedLocusNames=MCP_0518 {ECO:0000313|EMBL:BAI60590.1};
OS   Methanocella paludicola (strain DSM 17711 / JCM 13418 / NBRC 101707 /
OS   SANAE).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanocellales; Methanocellaceae; Methanocella.
OX   NCBI_TaxID=304371 {ECO:0000313|EMBL:BAI60590.1, ECO:0000313|Proteomes:UP000001882};
RN   [1] {ECO:0000313|Proteomes:UP000001882}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17711 / JCM 13418 / NBRC 101707 / SANAE
RC   {ECO:0000313|Proteomes:UP000001882};
RX   PubMed=21829548; DOI=10.1371/journal.pone.0022898;
RA   Sakai S., Takaki Y., Shimamura S., Sekine M., Tajima T., Kosugi H.,
RA   Ichikawa N., Tasumi E., Hiraki A.T., Shimizu A., Kato Y., Nishiko R.,
RA   Mori K., Fujita N., Imachi H., Takai K.;
RT   "Genome sequence of a mesophilic hydrogenotrophic methanogen Methanocella
RT   paludicola, the first cultivated representative of the order
RT   Methanocellales.";
RL   PLoS ONE 6:E22898-E22898(2011).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + L-arginine = agmatine + CO2; Xref=Rhea:RHEA:17641,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:32682,
CC         ChEBI:CHEBI:58145; EC=4.1.1.19; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_01404};
CC   -!- COFACTOR:
CC       Name=pyruvate; Xref=ChEBI:CHEBI:15361;
CC         Evidence={ECO:0000256|HAMAP-Rule:MF_01404};
CC       Note=Binds 1 pyruvoyl group covalently per subunit. {ECO:0000256|HAMAP-
CC       Rule:MF_01404};
CC   -!- SIMILARITY: Belongs to the PdaD family. {ECO:0000256|HAMAP-
CC       Rule:MF_01404}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AP011532; BAI60590.1; -; Genomic_DNA.
DR   STRING; 304371.MCP_0518; -.
DR   EnsemblBacteria; BAI60590; BAI60590; MCP_0518.
DR   KEGG; mpd:MCP_0518; -.
DR   PATRIC; fig|304371.9.peg.533; -.
DR   eggNOG; arCOG04490; Archaea.
DR   eggNOG; COG1945; LUCA.
DR   HOGENOM; HOG000012204; -.
DR   KO; K02626; -.
DR   OMA; SEHHSFG; -.
DR   Proteomes; UP000001882; Chromosome.
DR   GO; GO:0008792; F:arginine decarboxylase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006527; P:arginine catabolic process; IEA:InterPro.
DR   Gene3D; 3.50.20.10; -; 1.
DR   HAMAP; MF_01404; PvlArgDC; 1.
DR   InterPro; IPR016104; Pyr-dep_his/arg-deCO2ase.
DR   InterPro; IPR016105; Pyr-dep_his/arg-deCO2ase_sand.
DR   InterPro; IPR002724; Pyruvoyl-dep_arg_deCO2ase.
DR   PANTHER; PTHR40438; PTHR40438; 1.
DR   Pfam; PF01862; PvlArgDC; 1.
DR   PIRSF; PIRSF005216; Pyruvoyl-dep_arg_deCO2ase; 1.
DR   SFLD; SFLDG01170; Pyruvoyl-dependent_arginine_de; 1.
DR   SUPFAM; SSF56271; SSF56271; 1.
DR   TIGRFAMs; TIGR00286; TIGR00286; 1.
PE   3: Inferred from homology;
DR   PRODOM; D1YVW8.
DR   SWISS-2DPAGE; D1YVW8.
KW   Decarboxylase {ECO:0000256|HAMAP-Rule:MF_01404};
KW   Lyase {ECO:0000256|HAMAP-Rule:MF_01404};
KW   Pyruvate {ECO:0000256|HAMAP-Rule:MF_01404};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001882}.
FT   CHAIN           1..39
FT                   /note="Pyruvoyl-dependent arginine decarboxylase subunit
FT                   beta"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01404"
FT                   /id="PRO_5023273058"
FT   CHAIN           40..161
FT                   /note="Pyruvoyl-dependent arginine decarboxylase subunit
FT                   alpha"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01404"
FT                   /id="PRO_5023273059"
FT   SITE            39..40
FT                   /note="Cleavage (non-hydrolytic)"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01404"
FT   MOD_RES         40
FT                   /note="Pyruvic acid (Ser)"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01404"
SQ   SEQUENCE   161 AA;  17761 MW;  759CB9443B037289 CRC64;
     MPKKVFFTTG VGRHKEMLES FEMALRDAGI EKFNLVTVSS ILPPGCIIVE RSEGLKELVP
     GEIVFTVMSR NSSNEPSRRI AAAIGCAIPA DSQADFGYLS EHHSYGESEE CAGKYAGELA
     REMFYTWKNE YPLRISYAAR SAEVDEDGNW ATVLAAAVFI L
//

If you have problems or comments...

PBIL Back to PBIL home page