(data stored in SCRATCH zone)

SWISSPROT: D1YW21_METPS

ID   D1YW21_METPS            Unreviewed;       348 AA.
AC   D1YW21;
DT   09-FEB-2010, integrated into UniProtKB/TrEMBL.
DT   09-FEB-2010, sequence version 1.
DT   11-DEC-2019, entry version 41.
DE   SubName: Full=Calcium/proton exchanger {ECO:0000313|EMBL:BAI60643.1};
GN   OrderedLocusNames=MCP_0571 {ECO:0000313|EMBL:BAI60643.1};
OS   Methanocella paludicola (strain DSM 17711 / JCM 13418 / NBRC 101707 /
OS   SANAE).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanocellales; Methanocellaceae; Methanocella.
OX   NCBI_TaxID=304371 {ECO:0000313|EMBL:BAI60643.1, ECO:0000313|Proteomes:UP000001882};
RN   [1] {ECO:0000313|Proteomes:UP000001882}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17711 / JCM 13418 / NBRC 101707 / SANAE
RC   {ECO:0000313|Proteomes:UP000001882};
RX   PubMed=21829548; DOI=10.1371/journal.pone.0022898;
RA   Sakai S., Takaki Y., Shimamura S., Sekine M., Tajima T., Kosugi H.,
RA   Ichikawa N., Tasumi E., Hiraki A.T., Shimizu A., Kato Y., Nishiko R.,
RA   Mori K., Fujita N., Imachi H., Takai K.;
RT   "Genome sequence of a mesophilic hydrogenotrophic methanogen Methanocella
RT   paludicola, the first cultivated representative of the order
RT   Methanocellales.";
RL   PLoS ONE 6:E22898-E22898(2011).
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DR   EMBL; AP011532; BAI60643.1; -; Genomic_DNA.
DR   STRING; 304371.MCP_0571; -.
DR   EnsemblBacteria; BAI60643; BAI60643; MCP_0571.
DR   KEGG; mpd:MCP_0571; -.
DR   eggNOG; ENOG4102TV4; Archaea.
DR   eggNOG; COG0387; LUCA.
DR   HOGENOM; HOG000083011; -.
DR   KO; K07300; -.
DR   OMA; AAVMITC; -.
DR   BioCyc; MPAL304371:GI7G-585-MONOMER; -.
DR   Proteomes; UP000001882; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015369; F:calcium:proton antiporter activity; IEA:InterPro.
DR   InterPro; IPR004713; CaH_exchang.
DR   InterPro; IPR004798; CAX.
DR   InterPro; IPR004837; NaCa_Exmemb.
DR   Pfam; PF01699; Na_Ca_ex; 2.
DR   TIGRFAMs; TIGR00846; caca2; 1.
DR   TIGRFAMs; TIGR00378; cax; 1.
PE   4: Predicted;
DR   PRODOM; D1YW21.
DR   SWISS-2DPAGE; D1YW21.
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001882};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        7..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        30..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        60..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        95..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        128..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        159..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        203..225
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        237..259
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        271..294
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        328..347
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          30..180
FT                   /note="Na_Ca_ex"
FT                   /evidence="ECO:0000259|Pfam:PF01699"
FT   DOMAIN          204..346
FT                   /note="Na_Ca_ex"
FT                   /evidence="ECO:0000259|Pfam:PF01699"
SQ   SEQUENCE   348 AA;  36821 MW;  269B3E16E2EF3460 CRC64;
     MKLDLDTILG AMLIFIPISI AAELLHLNGI IIFFTAALAI VPLAGFMGKA TEELSKQVGA
     GIGGLLNATF GNATELIIAI FALQAGLFEV VKASLTGGII GNMLLITGCS MFLGGLKREK
     QTFNSRVQGV NSTMLMIAAV GLVMPALVSH LFDFNTVEAL SLGISGILII AYVASLLFSL
     KTHKHLYDCG GEECKPHMSR NRAILLLLVT TAVIALESEI LVGAVESVSL SLGLSELFIG
     VIIVAIIGNA AEHSTAILMA MKNNMDLSMG IAMGSSTQIA LLIAPVLVFI SWFWGNPMDL
     VFNQFEVVAI IASVVIANMI SSDGESNWLE GAQLIALYAM MAVVFFLI
//

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